Results 231 to 240 of about 51,325 (311)

Development of targeted drug carriers for breast cancer therapy [PDF]

open access: yes, 2014
Artzi, Natalie   +3 more
core  

Clinical trial of safety and antitumor activity of farletuzumab ecteribulin in patients with platinum‐resistant ovarian cancer: Phase I expansion results

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective In the dose‐escalation part of Study 101, which included multiple tumor types, objective responses were observed in 10 of 22 patients across multiple dose levels of farletuzumab ecteribulin (FZEC). We explored the safety/antitumor activity of FZEC in patients with platinum‐resistant ovarian cancer (PROC) from the Study 101 expansion ...
Kan Yonemori   +11 more
wiley   +1 more source

Navigating the future of nano‐pesticides: A perspective on design, efficacy, mechanisms, and environmental stewardship

open access: yesiMeta, EarlyView.
Nano‐pesticides are driving a paradigm shift toward sustainable plant protection. This review systematically synthesizes recent advances across four interconnected domains: (i) intelligent formulation design for targeted delivery and controlled release; (ii) interfacial behavior regulation to enhance foliar deposition; (iii) multi‐omics elucidation of ...
Xile Deng   +14 more
wiley   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

open access: yesiNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid   +4 more
wiley   +1 more source

Recent advances in potential drug nanocarriers for CNS disorders: a review. [PDF]

open access: yesBiomed Eng Online
Saraswathi TS   +4 more
europepmc   +1 more source

Recent progress on stimuli‐responsive chitosan‐based biomaterials as drug carriers

open access: yesInterdisciplinary Medicine, EarlyView.
This review discusses the recent progress in chitosan‐based drug delivery systems that respond to pH, redox, enzymes, reactive oxygen species, and combined stimuli. It examines design strategies, key mechanisms, and therapeutic applications, and also addresses current challenges while suggesting future approaches to enhance clinical translation and ...
Changlu Xu   +4 more
wiley   +1 more source

Engineered extracellular vesicles for precision renal therapy: Bioengineering strategies and clinical translation

open access: yesInterdisciplinary Medicine, EarlyView.
Engineered extracellular vesicles (EVs) offer a versatile platform for kidney‐targeted therapy. This review summarizes bioengineering strategies, including cargo loading, surface modification, biomimetic fabrication, and biomaterial integration. We highlight translational challenges and propose future solutions to accelerate the clinical application of
Linru Shi   +6 more
wiley   +1 more source

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