Technology in Cancer Research & Treatment, 2021 Although Epirubicin (EPI) is a commonly used anthracycline for the treatment of breast cancer in clinic, the serious side effects limit its long-term administration including myelosuppression and cardiomyopathy. Nanomedicines have been widely utilized as
Yayan Yang BS +6 more
doaj +1 more source
Evaluation of lipid nanocarriers in the form of SLN and their application in drug delivery and medical science [PDF]
Nanochemistry Research, 2023 Currently, most drugs reach to their place where they can have their desired effects through traditional methods and systemic absorption. Drugs are associated with many problems and complications in drug delivery systems the aim of which is reducing the ...
Mohammad Hossein Malekipour Esfahani +2 more
doaj +1 more source
Chaperonins: Nanocarriers with Biotechnological Applications [PDF]
Nanomaterials, 2021 Chaperonins are molecular chaperones found in all kingdoms of life, and as such they assist in the folding of other proteins. Structurally, chaperonins are cylinders composed of two back-to-back rings, each of which is an oligomer of ~60-kDa proteins.
Sergio Pipaón +7 more
openaire +5 more sources
Micellar dye shuttle between water and an ionic liquid [PDF]
, 2011 The reversible transfer of poly(2-ethyl-2-oxazoline)-block-poly(2-nonyl-2-oxazoline) nanocarriers comprising encapsulated dyes is demonstrated between water and an ionic liquid. This dye transfer concept is shown to be applicable for loading and delivery
Guerrero-Sanchez, Carlos +4 more
core +2 more sources
The influence of natural pulmonary surfactant on the efficacy of siRNA-loaded dextran nanogels [PDF]
, 2013 Aim: Topical administration of siRNA nanocarriers is a promising approach in the treatment of pulmonary disorders. Pulmonary surfactant, covering the entire alveolar surface of mammalian lungs, will be one of the first interfaces that siRNA nanocarriers ...
Braeckmans, Kevin +4 more
core +1 more source
Application of Polymeric Nanocomposites Prepared via Reversible Addition-Fragmentation Chain-Transfer (RAFT) Polymerization in Drug Delivery: A Brief Review [PDF]
Baspārish, 2022 Recently, the use of controlled-radical polymerization methods for the preparation of various polymer materials has received much attention due to the advantages of these methods and the elimination of the disadvantages of radical polymerization.
Ali Pourjavadi +2 more
doaj +1 more source
A novel diblock copolymer of (monomethoxy poly [ethylene glycol]-oleate) with a small hydrophobic fraction to make stable micelles/polymersomes for curcumin delivery to cancer cells [PDF]
, 2014 Curcumin is a potent natural anticancer agent, but its effectiveness is limited by properties such as very low solubility, high rate of degradation, and low rate of absorption of its hydrophobic molecules in vivo.
Erfani-Moghadam, V. +5 more
core +2 more sources
Preparation and Characterization of New Liposomes. Bactericidal Activity of Cefepime Encapsulated into Cationic Liposomes [PDF]
, 2019 Cefepime is an antibiotic with a broad spectrum of antimicrobial activity. However, this antibiotic has several side effects and a high degradation rate.
Camacho Sánchez, Vanesa +6 more
core +1 more source
Journal of the Formosan Medical Association, 2019 Background/Purpose: Primary cells are sensitive to culture conditions, which can be more difficult to get efficient transfection. The purpose of this study is to develop a serum-compatible cholesterol-based nanocarrier for delivering therapeutic nucleic ...
Karen Chang +2 more
doaj +1 more source
Dendrimer Conjugation Enhances Tumor Penetration and Cell Kill of Doxorubicin in 3D Coculture Lung Cancer Models [PDF]
, 2020 Background: Doxorubicin (DOX) is a potent chemotherapeutic widely used for solid tumors (1). Despite high efficacy in 2D cell culture, DOX efficacy does not translate to in vivo lung cancer models (2).
Almuqbil, Rashed +5 more
core +1 more source