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The Evolution of Nanopore Sequencing [PDF]

open access: yesFrontiers in Genetics, 2015
The $1,000 Genome project has been drawing increasing attention since its launch a decade ago. Nanopore sequencing, the third-generation, is believed to be one of the most promising sequencing technologies to reach four gold standards set for the $1,000 ...
Yue eWang, Qiuping eYang, Zhimin eWang
doaj   +3 more sources

The diagnostic value of Xpert detection combined with nanopore sequencing for tuberculosis in HIV/AIDS patients [PDF]

open access: yesInfectious Medicine
Background: Tuberculosis (TB) remains a major cause of death in HIV/AIDS patients, where diagnosis is complicated by atypical presentation and paucibacillary disease. Current diagnostic methods have limitations in speed or sensitivity.
Chang Song   +10 more
doaj   +2 more sources

The applications and advantages of nanopore sequencing in bacterial antimicrobial resistance surveillance and research [PDF]

open access: yesnpj Antimicrobials and Resistance
Genomics research is essential for understanding the transmission and evolution of bacterial antimicrobial resistance. The development of nanopore long-read sequencing has revolutionized our understanding of the prevalence, spread, and dynamic evolution ...
Kai Peng   +5 more
doaj   +2 more sources

Nanopore sequencing technology and its applications

open access: yesMedComm, 2023
Since the development of Sanger sequencing in 1977, sequencing technology has played a pivotal role in molecular biology research by enabling the interpretation of biological genetic codes.
Peijie Zheng   +6 more
doaj   +3 more sources

Nanopore sequencing in microgravity [PDF]

open access: yesnpj Microgravity, 2016
Abstract Rapid DNA sequencing and analysis has been a long-sought goal in remote research and point-of-care medicine. In microgravity, DNA sequencing can facilitate novel astrobiological research and close monitoring of crew health, but spaceflight places stringent restrictions on the mass and volume of ...
Alexa B R McIntyre   +12 more
openaire   +4 more sources

Utility of nanopore sequencing for detecting pathogens in bronchoalveolar lavage fluid from pediatric patients with respiratory failure

open access: yesJournal of Clinical Virology Plus, 2023
RNA viruses are the most frequent pathogens responsible for respiratory infections, particularly in pediatric patients. Next-generation sequencing, represented by Illumina sequencing, is one of the most comprehensive methods for identifying pathogens ...
Makoto Yamaguchi   +11 more
doaj   +1 more source

An Introduction to Nanopore Sequencing: Past, Present, and Future Considerations

open access: yesMicromachines, 2023
There has been significant progress made in the field of nanopore biosensor development and sequencing applications, which address previous limitations that restricted widespread nanopore use.
Morgan MacKenzie, Christos Argyropoulos
doaj   +1 more source

Applications and potentials of nanopore sequencing in the (epi)genome and (epi)transcriptome era

open access: yesThe Innovation, 2021
Summary: The Human Genome Project opened an era of (epi)genomic research, and also provided a platform for the development of new sequencing technologies.
Shangqian Xie   +7 more
doaj   +1 more source

Freshwater monitoring by nanopore sequencing [PDF]

open access: yeseLife, 2020
ABSTRACTWhile traditional microbiological freshwater tests focus on the detection of specific bacterial indicator species, including pathogens, direct tracing of all aquatic DNA through metagenomics poses a profound alternative. Yet,in situmetagenomic water surveys face substantial challenges in cost and logistics.
Urban, Lara   +11 more
openaire   +5 more sources

The Power of Using Novel Nanopore Sequencing Technology for Diagnosis, Genomic and Pathological Studies of Covid-19 [PDF]

open access: yesE3S Web of Conferences, 2021
The novel coronavirus disease 2019 (COVID‐19), originally identified in December 2019 Wuhan, China, has propagated to worldwide pandemic, causing many cases of death and morbidity.
Du Chenghao
doaj   +1 more source

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