Results 221 to 230 of about 65,196 (347)

Rapid reconstruction of multidrug‐resistant bacterial genomes using CycloneSEQ nanopore sequencing

iMetaOmics, EarlyView.
Multidrug‐resistant (MDR) bacteria commonly harbor highly complex genomes enriched with mobile elements and resistance islands, which are challenging to resolve using short‐read sequencing. Here, we evaluated CycloneSEQ, a newly developed Chinese nanopore sequencing platform, for MDR genome reconstruction.
Kai Peng, Zeyu Tong, Changan Li, Zhichao Li, Xin Lu, Cemil Kurekci, Mashkoor Mohsin, Zhiqiang Wang, Yong‐Xin Liu, Ruichao Li   +9 more
wiley   +1 more source

ECCFP: A consecutive full pass‐based bioinformatic analysis for eccDNA identification from long‐read sequencing data

iMetaOmics, EarlyView.
A new bioinformatics pipeline called ECCFP has been developed to improve the detection of extrachromosomal circular DNA (eccDNA) from long‐read sequencing data. ECCFP uses all consecutive full passes from individual reads for candidate eccDNA identification and consolidates candidate eccDNAs to generate accurate unique eccDNA.
Wang Li, Biyuan Miao, Jun Zhang, Qingsong Zeng, Tangxuan Zhang, Zetong Wu, Yusheng Song, Mengting Li, Lilu Guo, Juan Luo, Jingxiang Xu, Tianliang Liu, Shifu Chen, Jia Gu, Shaogui Wan   +14 more
wiley   +1 more source

A comprehensive benchmarking of adaptive sampling tools for nanopore sequencing. [PDF]

Genome Biol
Yang L, Lin Y, Li P, Wang K, Li J, Liu Y, Bo X, Ni M, Li P, Song H.   +9 more
europepmc   +1 more source

Fast bootstrap and reliable readout using hidden references for DNA data storage

iMeta, EarlyView.
This study provides a bootstrap readout framework for DNA data storage based on multiple‐fold hidden references. We employ a multi‐stage alignment and error correction strategy, transforming the de novo readout into a resequencing‐like workflow. Correlation to the hidden watermark reference identifies low‐error‐rate reads, and bit‐wise consensus ...
Weigang Chen, Shuang Liu, Quan Guo, Rui Qin, Qi Ge, Tingting Qi, Yingjin Yuan   +6 more
wiley   +1 more source

Evaluation of a Probe-Based Enrichment Protocol for Nanopore Sequencing of Zoonotic Viruses. [PDF]

Viruses
Hawes K, Greene B, Weishampel ZA, Beare PA, van Tol S, Schaughency P, Kuhn S, Peel AJ, Munster VJ, Yinda CK.   +9 more
europepmc   +1 more source

Progress in nanopore sequencing [PDF]

Nature Reviews Genetics, 2014
openaire   +1 more source

Majorbio Cloud 2026 provides comprehensive analysis workflows for microbiome

iMeta, EarlyView.
The integrated microbiome data analysis platform on Majorbio Cloud (https://cloud.majorbio.com/) encompasses 26 analytical workflows, with a core architecture of two modules: single‐omics workflows and cross‐omics integration and correlation workflows.
Jianhua Zhao, Linmeng Liu, Jichen Han, Junbiao Zhang, Xiaodan Li, Yan Wang, Qianhui Han, Xue Gong, Linna Zhang, Hao Gao, Bing Yang, Yachen Dong, Huasheng Huang, Xianglin Zhang, Kegang Yu   +14 more
wiley   +1 more source

Exploiting nanopore sequencing advances for tRNA sequencing of human cancer models. [PDF]

NAR Cancer
Kochavi A, Velds A, Suzuki M, Akichika S, Suzuki T, Beijersbergen RL, Agami R.   +6 more
europepmc   +1 more source

Identification of a De Novo MAGEL2 Pathogenic Variant in Schaaf–Yang Syndrome and the Importance of Paternal Allele Confirmation

Journal of Clinical Laboratory Analysis, EarlyView.
This study reports a de novo MAGEL2 pathogenic variant in a patient with Schaaf–Yang syndrome, confirmed through methylation‐sensitive analysis. Combining genomic sequencing with methylation assays helps accurately determine the parental origin of MAGEL2 mutations.
Youn‐Ji Hong, Misun Yang, Hyeon Jeong Kwon, Jooyoung Cha, Ja‐Hyun Jang, Sung Eun Wang, Eun Sun Lee, Mi‐Ae Jang   +7 more
wiley   +1 more source

Employing nanopore sequencing on FFPE-derived DNA for CNS tumor diagnostics. [PDF]

Acta Neuropathol Commun
Kerbs P, Brehm M, Haag D, Bogumil H, Patel A, Sill M, Berghaus N, Göbel K, Schrimpf D, Tabatabai G, Schittenhelm J, Sakowitz O, Stadelmann C, Goldbrunner R, Etminan N, Ratliff M, Herold-Mende C, Krieg S, Wick W, Jones DTW, von Deimling A, Sahm F, Göller P.   +22 more
europepmc   +1 more source