Results 241 to 250 of about 47,109 (297)

Resolving plasmid-encoded carbapenem resistance dynamics and reservoirs in a hospital setting through nanopore sequencing. [PDF]

Microb Genom
Sauerborn E, White RT, Kalteis AL, Gygax D, Foster-Nyarko E, Wantia N, Gebhardt F, Urban L.   +7 more
europepmc   +1 more source

Unveiling Gut Homeostasis Disruption in Sepsis: Towards an Integrated Mechanistic and Translational Roadmap

Cell Proliferation, EarlyView.
Elucidating the contribution of gut‐organ axes will provide new insights for developing combined therapeutic strategies against sepsis‐associated multiple organ dysfunction. ABSTRACT Sepsis, a life‐threatening clinical syndrome precipitated by a maladaptive host response to infection, is associated with substantial morbidity and high mortality rates ...
Yichen Bao, Lin Qi, Guijun Zou, Xingpeng Yang, Yizhao Ma, Zhifu Li, Xiaohui Du, Pengyue Zhao   +7 more
wiley   +1 more source

Unlocking the full potential of nanopore sequencing: tips, tricks, and advanced data analysis techniques. [PDF]

Nucleic Acids Res
Meyer D, Goettsch W, Spangenberg J, Stieber B, Krautwurst S, Hölzer M, Brandt C, Linde J, Höner Zu Siederdissen C, Srivastava A, Zarkovic M, Wollny D, Marz M.   +12 more
europepmc   +1 more source

Long‐read sequencing‐based atlas of tissue‐specific expression of DNM1L transcript variants

The FEBS Journal, EarlyView.
Targeted long‐read sequencing resolves full‐length DNM1L (Drp1) isoforms and reveals conserved, tissue‐specific expression patterns across human and mouse tissues. Functional assays show that Drp1 isoforms differ in their ability to drive mitochondrial fission, independent of abundance, with specific exons modulating activity.
Feng Yan, Jafar S. Jabbari, Naomi X. L. Ling, Anne M. Kong, Jia Q. Truong, Marnie L. Maddock, Ayeshah A. Rosdah, Christopher G. Langendorf, Lifang Zhang, Jarmon G. Lees, Sebastian Bass‐Stringer, Danise Ann Onda, Alice Pébay, Mirella Dottori, Kim Loh, Jessica K. Holien, Sean Lal, Nadia M. Davidson, Jonathan S. Oakhill, Shiang Y. Lim   +19 more
wiley   +1 more source

The applications and advantages of nanopore sequencing in bacterial antimicrobial resistance surveillance and research. [PDF]

NPJ Antimicrob Resist
Peng K, Li C, Wang Q, Xin X, Wang Z, Li R.   +5 more
europepmc   +1 more source

Can Artificial Intelligence Be Utilised to Develop Point‐of‐Care Endodontic Microbiological Technologies?

International Endodontic Journal, EarlyView.
ABSTRACT Background Primary or persistent endodontic disease is caused by microbial biofilms that irritate the pulp and periapical tissues. Extensive microbiological analyses of these biofilms and their constituent pathogens have revealed their diversity and complexity.
Ashraf F. Fouad
wiley   +1 more source

cuteSV-OL: a real-time structural variation detection framework for nanopore sequencing devices. [PDF]

Bioinformatics
Guo W, Liu Y, Wang Y, Jiang T.
europepmc   +1 more source

Mapping human pre-rRNA processing and modification at single nucleotide resolution using long read nanopore sequencing. [PDF]

Nat Commun
Pastore S, Wacheul L, Lehmann L, Mündnich S, Lutz B, Helm M, Gerber S, Lafontaine DLJ, Butto T.   +8 more
europepmc   +1 more source

Evaluation of a Probe-Based Enrichment Protocol for Nanopore Sequencing of Zoonotic Viruses. [PDF]

Viruses
Hawes K, Greene B, Weishampel ZA, Beare PA, van Tol S, Schaughency P, Kuhn S, Peel AJ, Munster VJ, Yinda CK.   +9 more
europepmc   +1 more source

Validation of an optimised Oxford Nanopore sequencing workflow versus Illumina for mycobacteria from primary MGIT culture

Baker CS, Colpus M, Gentry J, Hall A, Roghi E, Webster H, Drummond B, Cooper R, Thai H, Westhead J, Turner R, Peto TE, Fowler PW, Morgan M, Crook DW.   +14 more
europepmc   +1 more source