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Nanopore Sequencing for Mixed Samples
2023Long read Nanopore sequencing can be utilised to determine the quality and accuracy of genetically engineered changes in animals, which often produce heterogenous samples. The protocol presented in this chapter can be used for a range of both low and high throughput sequencing applications.
Angela H, Beckett, Samuel C, Robson
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Nanotechnology and Nanopore Sequencing
Recent Patents on Nanotechnology, 2017DNA sequencing is one of the crucially important tasks in the fields of genetics and cellular biology, which is benefiting from nanotechnology. DNA carries genetic information and sequencing it in a quick way helps researchers in achieving essential goals, including personalized medicine.
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The Current State of Nanopore Sequencing
2023Nanopore sensing is a disruptive, revolutionary way in which to sequence nucleic acids, including both native DNA and RNA molecules. First commercialized with the MinIONTM sequencer from Oxford Nanopore TechnologiesTM in 2015, this review article looks at the current state of nanopore sequencing as of June 2022.
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Nanopore RNA Sequencing Analysis
2021The recent advent of Nanopore sequencing allows for the sequencing of full-length RNA or cDNA molecules. This new type of data introduces new challenges from the computational point of view, and requires new software as well as dedicated analysis pipelines.
Tommaso, Leonardi, Adrien, Leger
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Nanopore sequencing meets epigenetics
Nature Methods, 2017Advanced signal processing techniques enable the genome-wide analysis of methylation in native DNA using nanopore sequencing.
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Advances in Nanopore Sequencing Technology
Journal of Nanoscience and Nanotechnology, 2013Much tremendous break through have been obtained in recent years for nanopore sequencing to achieve the goal of $1000 genome. As a method of single molecule sequencing, nanopore sequencing can discriminate the individual molecules of the target DNA strand rapidly due to the current blockages by translocating the nucleotides through a nano-scale pore ...
Yongqiang, Yang +6 more
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Sequence reconstruction in nanopore sequencing
2019In dieser Diplomarbeit geht es um Nanopore-Sequenzierung. Bei dieser Methode wird ein einsträngiges DNA-Oligomer durch eine winzige Pore gezogen. Elektrischer Strom fließt anschließend durch diese Pore und wird durch die darin befindlichen Basen unterschiedlich stark moduliert.
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Modeling Nanopores for Sequencing DNA
2011Using nanopores to sequence DNA rapidly and at a low cost has the potential to radically transform the field of genomic research. However, despite all the exciting developments in the field, sequencing DNA using a nanopore has yet to be demonstrated. Among the many problems that hinder development of the nanopore sequencing methods is the inability of ...
Jeffrey R, Comer +2 more
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