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Nanopore RNA Sequencing Analysis
2021The recent advent of Nanopore sequencing allows for the sequencing of full-length RNA or cDNA molecules. This new type of data introduces new challenges from the computational point of view, and requires new software as well as dedicated analysis pipelines.
Tommaso, Leonardi, Adrien, Leger
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Nanopore sequencing technology: nanopore preparations
Trends in Biotechnology, 2007For the past decade, nanometer-scale pores have been developed as a powerful technique for sensing biological macromolecules. Various potential applications using these nanopores have been reported at the proof-of-principle stage, with the eventual aim of using them as an alternative to de novo DNA sequencing.
Minsoung, Rhee, Mark A, Burns
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Bioinformatics of nanopore sequencing
Journal of Human Genetics, 2019Nanopore sequencing is one of the most exciting new technologies that undergo dynamic development. With its development, a growing number of analytical tools are becoming available for researchers. To help them better navigate this ever changing field, we discuss a range of software available to analyze sequences obtained using nanopore technology.
Wojciech Makałowski +1 more
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Nanopore Sequencing for Mixed Samples
2023Long read Nanopore sequencing can be utilised to determine the quality and accuracy of genetically engineered changes in animals, which often produce heterogenous samples. The protocol presented in this chapter can be used for a range of both low and high throughput sequencing applications.
Angela H, Beckett, Samuel C, Robson
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Nanotechnology and Nanopore Sequencing
Recent Patents on Nanotechnology, 2017DNA sequencing is one of the crucially important tasks in the fields of genetics and cellular biology, which is benefiting from nanotechnology. DNA carries genetic information and sequencing it in a quick way helps researchers in achieving essential goals, including personalized medicine.
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Nanopore sequencing meets epigenetics
Nature Methods, 2017Advanced signal processing techniques enable the genome-wide analysis of methylation in native DNA using nanopore sequencing.
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Microbial Genome Sequencing and Assembly Using Nanopore Sequencers
2023Microbial genomes are typically several million base pairs in length and are relatively easy to sequence and assemble into a single chromosome, given the advances in long-read sequencing platforms such as that of Oxford Nanopore Technologies. This chapter describes the experimental as well as computational steps in the sequencing and assembly of ...
Makoto, Taniguchi, Kazuma, Uesaka
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Advances in Nanopore Sequencing Technology
Journal of Nanoscience and Nanotechnology, 2013Much tremendous break through have been obtained in recent years for nanopore sequencing to achieve the goal of $1000 genome. As a method of single molecule sequencing, nanopore sequencing can discriminate the individual molecules of the target DNA strand rapidly due to the current blockages by translocating the nucleotides through a nano-scale pore ...
Yongqiang, Yang +6 more
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