Results 21 to 30 of about 998,588 (389)

Nanopore sequencing in microgravity [PDF]

open access: yesnpj Microgravity, 2016
Abstract Rapid DNA sequencing and analysis has been a long-sought goal in remote research and point-of-care medicine. In microgravity, DNA sequencing can facilitate novel astrobiological research and close monitoring of crew health, but spaceflight places stringent restrictions on the mass and volume of ...
Alexa B R McIntyre   +12 more
openaire   +4 more sources

Utility of nanopore sequencing for detecting pathogens in bronchoalveolar lavage fluid from pediatric patients with respiratory failure

open access: yesJournal of Clinical Virology Plus, 2023
RNA viruses are the most frequent pathogens responsible for respiratory infections, particularly in pediatric patients. Next-generation sequencing, represented by Illumina sequencing, is one of the most comprehensive methods for identifying pathogens ...
Makoto Yamaguchi   +11 more
doaj   +1 more source

Applications and potentials of nanopore sequencing in the (epi)genome and (epi)transcriptome era

open access: yesThe Innovation, 2021
Summary: The Human Genome Project opened an era of (epi)genomic research, and also provided a platform for the development of new sequencing technologies.
Shangqian Xie   +7 more
doaj   +1 more source

Nanopore sequencing of DNA-barcoded probes for highly multiplexed detection of microRNA, proteins and small biomarkers

open access: yesNature Nanotechnology, 2023
There is an unmet need to develop low-cost, rapid and highly multiplexed diagnostic technology platforms for quantitatively detecting blood biomarkers to advance clinical diagnostics beyond the single biomarker model.
Carolin Koch   +7 more
semanticscholar   +1 more source

Error-Correcting Codes for Nanopore Sequencing [PDF]

open access: yesIEEE Transactions on Information Theory, 2023
Nanopore sequencing, superior to other sequencing technologies for DNA storage in multiple aspects, has recently attracted considerable attention. Its high error rates, however, demand thorough research on practical and efficient coding schemes to enable
Anisha Banerjee   +3 more
semanticscholar   +1 more source

Freshwater monitoring by nanopore sequencing [PDF]

open access: yeseLife, 2020
ABSTRACTWhile traditional microbiological freshwater tests focus on the detection of specific bacterial indicator species, including pathogens, direct tracing of all aquatic DNA through metagenomics poses a profound alternative. Yet,in situmetagenomic water surveys face substantial challenges in cost and logistics.
Urban, Lara   +11 more
openaire   +5 more sources

The Power of Using Novel Nanopore Sequencing Technology for Diagnosis, Genomic and Pathological Studies of Covid-19 [PDF]

open access: yesE3S Web of Conferences, 2021
The novel coronavirus disease 2019 (COVID‐19), originally identified in December 2019 Wuhan, China, has propagated to worldwide pandemic, causing many cases of death and morbidity.
Du Chenghao
doaj   +1 more source

Nanopore Technology and Its Applications in Gene Sequencing

open access: yesBiosensors, 2021
In recent years, nanopore technology has become increasingly important in the field of life science and biomedical research. By embedding a nano-scale hole in a thin membrane and measuring the electrochemical signal, nanopore technology can be used to ...
Bo Lin, Jianan Hui, Hongju Mao
doaj   +1 more source

Nanopore direct RNA sequencing maps the complexity of Arabidopsis mRNA processing and m6A modification [PDF]

open access: yes, 2020
Understanding genome organization and gene regulation requires insight into RNA transcription, processing and modification. We adapted nanopore direct RNA sequencing to examine RNA from a wild-type accession of the model plant Arabidopsis thaliana and a ...
Barton, Geoffrey J.   +8 more
core   +3 more sources

Adaptation of Oxford Nanopore technology for hepatitis C whole genome sequencing and identification of within-host viral variants

open access: yesBMC Genomics, 2021
Background Hepatitis C (HCV) and many other RNA viruses exist as rapidly mutating quasi-species populations in a single infected host. High throughput characterization of full genome, within-host variants is still not possible despite advances in next ...
Nasir Riaz   +7 more
doaj   +1 more source

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