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Requirement of a leucine residue for (apical) membrane expression of type IIb NaPi cotransporters
Type II NaPi cotransporters mediate epithelial phosphate (P(i)) reabsorption. In mammals the type IIb protein is expressed in the small intestinal apical membrane and other epithelia; it is not expressed in the renal proximal tubule where we find the ...
Nati Hernando, Jürg Biber, J Biber
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During metabolic acidosis, Pi serves as an important buffer to remove protons from the body. Pi is released from bone together with carbonate buffering protons in blood. In addition, in the kidney, the fractional excretion of phosphate is increased allowing for the excretion of more acid equivalents in urine.
A. Stauber +5 more
semanticscholar +4 more sources
Cancer Research, 2014
Abstract Background: Lung cancer (LC) represents a major health challenge worldwide, being the leading cause of cancer-related deaths in both men and women. SLC34A2 is a member of the solute carrier family and encodes the type IIb sodium phosphate cotransporter (NaPi-IIb).
M. F. Cerri +7 more
semanticscholar +2 more sources
Abstract Background: Lung cancer (LC) represents a major health challenge worldwide, being the leading cause of cancer-related deaths in both men and women. SLC34A2 is a member of the solute carrier family and encodes the type IIb sodium phosphate cotransporter (NaPi-IIb).
M. F. Cerri +7 more
semanticscholar +2 more sources
The objective of this experiment was to determine if dietary vitamin D supplementation to vitamin D deficient pigs affects Na+-dependent nutrient uptake and mRNA expression of NaPi-IIb and calbindi...
Kari L. Saddoris +3 more
semanticscholar +2 more sources
Regulation of intestinal sodium phosphate cotransporter (NaPi-IIb) gene expression by estrogen
Gastroenterology, 2003Hua Xu +5 more
openaire +1 more source
EGF regulation on the human intestinal NaPi-IIb gene expression involves c-Myb
Gastroenterology, 2003Hua Xu +4 more
openaire +1 more source
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2016
Da-Neng Wang, Nathan Karpowich
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Da-Neng Wang, Nathan Karpowich
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