Results 11 to 20 of about 43,002 (287)

Narcolepsy Diagnosis With Sleep Stage Features Using PSG Recordings

open access: yesIEEE Transactions on Neural Systems and Rehabilitation Engineering, 2023
Narcolepsy is a sleep disorder affecting millions of people worldwide and causes serious public health problems. It is hard for doctors to correctly and objectively diagnose narcolepsy.
Jiquan Wang   +7 more
doaj   +2 more sources

Increased very low frequency pulsations and decreased cardiorespiratory pulsations suggest altered brain clearance in narcolepsy

open access: yesCommunications Medicine, 2022
Järvelä et al. investigate if narcolepsy is associated with altered brain pulsations using ultrafast fMRI. They find differences in the brain pulsations between narcolepsy type 1 patients and healthy controls that may link to altered brain clearance in ...
Matti Järvelä   +5 more
doaj   +2 more sources

European guideline and expert statements on the management of narcolepsy in adults and children

open access: yesEuropean Journal of Neurology, 2021
Narcolepsy is an uncommon hypothalamic disorder of presumed autoimmune origin that usually requires lifelong treatment. This paper aims to provide evidence‐based guidelines for the management of narcolepsy in both adults and children.
C. Bassetti   +17 more
semanticscholar   +2 more sources

Epigenetic silencing of selected hypothalamic neuropeptides in narcolepsy with cataplexy

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2023
Significance Narcolepsy with cataplexy is characterized by excessive daytime sleepiness and sudden loss of muscle tone (cataplexy) triggered by strong emotions.
A. Seifinejad   +20 more
semanticscholar   +1 more source

Orexin 2 receptor–selective agonist danavorexton improves narcolepsy phenotype in a mouse model and in human patients

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2022
Significance Despite the discovery of the orexin (hypocretin) neuropeptides in 1998 and their role in narcolepsy type 1 (NT1), current pharmacotherapy addresses only the associated symptoms and not the underlying loss of orexin. Danavorexton (TAK-925) is
R. Evans   +13 more
semanticscholar   +1 more source

Cardiovascular Burden of Narcolepsy Disease (CV-BOND): a real-world evidence study

open access: yesSleep, 2022
Study Objectives Narcolepsy is associated with cardiovascular risk factors; however, the risk of new-onset cardiovascular events in this population is unknown.
R. Ben-Joseph   +6 more
semanticscholar   +1 more source

Health-related stigma as a determinant of functioning in young adults with narcolepsy. [PDF]

open access: yesPLoS ONE, 2015
Symptoms of narcolepsy tend to arise during adolescence or young adulthood, a formative time in human development during which people are usually completing their education and launching a career.
Mary C Kapella   +5 more
doaj   +1 more source

Disrupted nighttime sleep and sleep instability in narcolepsy

open access: yesJournal of Clinical Sleep Medicine (JCSM), 2021
This review aimed to summarize current knowledge about disrupted nighttime sleep (DNS) and sleep instability in narcolepsy, including self-reported and objective assessments, potential causes of sleep instability, health consequences and functional ...
K. Maski   +3 more
semanticscholar   +1 more source

Cardiovascular disorders in narcolepsy: Review of associations and determinants.

open access: yesSleep Medicine Reviews, 2021
Narcolepsy type 1 (NT1) is a lifelong disorder of sleep-wake dysregulation defined by clinical symptoms, neurophysiological findings, and low hypocretin levels.
P. Jennum   +4 more
semanticscholar   +1 more source

Diagnosis and treatment of narcolepsy and parasomnias

open access: yesSichuan jingshen weisheng, 2021
The purpose of this article is to discuss the clinical diagnosis and treatment of narcolepsy and parasomnias. In view of high probability and great harm of missed diagnosis and misdiagnosis of narcolepsy, as well as its close association with parasomnias,
Zhou Junying
doaj   +1 more source

Home - About - Disclaimer - Privacy