Results 131 to 140 of about 1,393 (162)
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On the ability of narcotic antagonists to produce the narcotic cue.
The Journal of Pharmacology and Experimental Therapeutics, 1976The ability of narcotic antagonists to produce the narcotic cue was investigated in rats trained to discriminate fentanyl (0.04 mg/kg) from solvent. The partial antagonists pentazocine, cyclazocine and nalorphine were found to possess narcotic cuing activity whereas naloxone lacked any such action at doses up to 160 mg/kg.
F C, Colpaert +2 more
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Journal of Medicinal Chemistry, 1975
A series of new narcotic antagonists has been synthesized by modifying the C-6 carbonyl group in naloxone (Ia) and naltrexone (Ib). New functional units were introduced by reaction with various phosphorus and sulfur ylides and alkyllithium reagents.
Hahn Ef, Fishman J, Heilman Rd
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A series of new narcotic antagonists has been synthesized by modifying the C-6 carbonyl group in naloxone (Ia) and naltrexone (Ib). New functional units were introduced by reaction with various phosphorus and sulfur ylides and alkyllithium reagents.
Hahn Ef, Fishman J, Heilman Rd
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Community Outcome on Narcotic Antagonists [PDF]
, 1979 As described at the outset of this book, there were two general goals of this research program: (1) a multivariate assessment of blocked and unblocked heroin consumption in order to characterize the nature of opioid reinforcement and (2) an approach to developing and evaluating narcotic antagonist treatment for the individual addict.
Steven M. Mirin +2 more
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Aftercare on Narcotic Antagonists: Prospects and Problems
International Journal of the Addictions, 1976This study examines the problems and prospects of aftercare of the multiple treatment failure opiate addict who is being treated with narcotic antagonists (primarily naltrexone). At the time of this paper, 21 patients had been admitted to the Drug Addiction Research Project at McLean Hospital, with a retention rate of 42%. "Completers," "noncompleters,"
Maxine Rawlins +4 more
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Narcotic and Narcotic Antagonist Analgesics
Annual Review of Pharmacology, 1967L S Harris, H F Fraser
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Recent Progress in Research on Narcotic Antagonists
1976In Volume 8 of this series Archer and Harris [7] reviewed the chemistry and pharmacology of narcotic antagonists. Since that time research in this field has increased enormously as evidenced by the fact that in the decade 1962–72 over 500 references to pentazocine have appeared in the literature.
William F. Michne, Sydney Archer
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Narcotics and Narcotic Antagonists
Anesthesiology, 1965Ephraim S. Siker +2 more
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Narcotic Analgesics and Antagonists
Annual Review of Pharmacology, 1971K W Bentley, J W Lewis, A Cowan
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Binding of narcotics and narcotic antagonists to triphosphoinositide
Biochemical Pharmacology, 1976Horace H. Loh +3 more
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