Results 151 to 160 of about 558,945 (252)

Capturing the Full Range of Buprenorphine Treatment Response.

JAMA Psychiatry
Bailey AJ, Votaw VR, Weiss RD, McHugh RK.   +3 more
europepmc   +1 more source

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CLINICAL PHARMACOLOGY OF NARCOTIC ANTAGONISTS*

Annals of the New York Academy of Sciences, 1978
Both naloxone and naltrexone are effective narcotic antagonists with minimal agonistic effects and a wide margin of safety. Naloxone is useful in the treatment of narcotic overdose and it is helpful in the quantification of physical dependence. Naltrexone is pharmacologically successful as an orally effective, long-acting antagonist but its clinical ...
C P, O'Brien, R, Greenstein, J, Ternes, G E, Woody   +3 more
openaire   +3 more sources

Narcotic antagonists. 4. Carbon-6 derivatives of N-substituted noroxymorphones as narcotic antagonists

Journal of Medicinal Chemistry, 1975
A series of new narcotic antagonists has been synthesized by modifying the C-6 carbonyl group in naloxone (Ia) and naltrexone (Ib). New functional units were introduced by reaction with various phosphorus and sulfur ylides and alkyllithium reagents.
R D, Heilman, E F, Hahn, J, Fishman
openaire   +3 more sources

Discriminative Properties of Narcotic Antagonists

Psychopharmacology communications, 1977
There have been many recent reports characterizing the discriminative properties of morphine and related narcotic analgesics in a variety of experimental paradigms, predominantly in the rat (see preceding chapter). It is becoming increasingly evident that a strong association exists between the discriminative properties of these drugs in animals and ...
S G, Holtzman, H E, Shannon, G J, Schaefer   +2 more
openaire   +3 more sources

DISPOSITION OF NARCOTICS AND NARCOTIC ANTAGONISTS*

Annals of the New York Academy of Sciences, 1976
C. Inturrisi
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Use of narcotic antagonists to modify stereotypic self-licking, self-chewing, and scratching behavior in dogs.

Journal of the American Veterinary Medical Association, 1988
We evaluated 2 narcotic antagonists, naltrexone and nalmefene, for treatment of refractory self-licking, self-chewing, and scratching behavior in dogs. Eleven dogs with various irritative or pruritic disorders were medicated with naltrexone (1 mg/kg of ...
N. Dodman, Louis Shuster, Stephen D. White, Michael H. Court, Denise Parker, Ross Dixon   +5 more
semanticscholar   +1 more source

Investigation into the use of narcotic antagonists in the treatment of a stereotypic behavior pattern (crib-biting) in the horse.

American Journal of Veterinary Research, 1987
Crib-biting in horses is a repetitive behavior pattern which may involve the activation of both narcotic receptors and dopamine receptors in the CNS. Crib-biting frequency, determined in 7 nontreated horses under controlled conditions, was usually linear
N. Dodman, Louis Shuster, Michael H. Court, Ross Dixon   +3 more
semanticscholar   +1 more source

Narcotic Antagonists as Analgesics

Science, 1962
2-Dimethylallyl-5,9-dimethyl-2′-hydroxybenzomorphan (Win 20,228) was found to be a weak antagonist of morphine and meperidine, whereas 2-allyl-5-ethyl-2′-hydroxy-9-methyl-6,7-benzomorphan (Win 19,362) and 2-allyl-2′-hydroxy-5,9-dimethyl-6,7-benzomorphan (Win 19,631) were about three times as potent as nalorphine.
S, ARCHER, N F, ALBERTSON, L S, HARRIS, A K, PIERSON, J G, BIRD, A S, KEATS, J, TELFORD, C N, PAPADOPOULOS   +7 more
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COMPARATIVE STUDIES WITH NARCOTICS AND NARCOTIC ANTAGONISTS IN MAN

Acta Anaesthesiologica Scandinavica, 1964
ZUSAMMENFASSUNGBei 240 oberflächlich anaesthesierten Patienten, die keine Narkotika als Prämedikation erhalten hatten, wurden die Wirkungen auf Atmung und Kreislauf der folgenden Mittel, allein oder in verschiedenen Kombinationen verabreicht, untersucht: Morphin (0,2 oder 0,3 mg/kg), Oxymorphon(20 μ/kg),Levorphan (50μ/kg),Meperidin (1,5 und 2,0 mg/kg ...
F F, FOLDES, T A, TORDA
openaire   +2 more sources