Results 21 to 30 of about 6,614 (186)

Biodegradable polymeric prodrugs of naltrexone [PDF]

open access: yes, 1991
The development of a biodegradable polymeric drug delivery system for the narcotic antagonist naltrexone may improve patient compliance in the treatment of opiate addiction. Random copolymers consisting of the ¿-amino acids N5-(3-hydroxypropyl--glutamine
Adams, N.W.   +5 more
core   +2 more sources

A Theory of Natural Addiction [PDF]

open access: yes, 2007
Economic theories of rational addiction aim to describe consumer behavior in the presence of habit-forming goods. We provide a biological foundation for this body of work by formally specifying conditions under which it is optimal to form a habit.
Ainslie   +102 more
core   +1 more source

Swedish police officers' strategies when interviewing suspects who decline to answer questions

open access: yesLegal and Criminological Psychology, Volume 28, Issue 1, Page 45-59, February 2023., 2023
Abstract Purpose Research‐based interviewing techniques typically rely upon suspects being, at least partially, responsive and engaged in the conversation. To date, the scientific literature is more limited regarding situations where suspects exercise their legal right to silence.
Mikaela Magnusson   +4 more
wiley   +1 more source

Intranasal versus Intramuscular/Intravenous Naloxone for Pre-hospital Opioid Overdose: A Systematic Review and Meta-analysis [PDF]

open access: yes, 2019
Context: The present systematic review and meta-analysis aims to perform an extensive search in databases to compare the efficacy of the intranasal administration of naloxone with its intramuscular/intravenous administration in the pre-hospital ...
Amiri, Marzieh   +6 more
core   +5 more sources

Counteraction of Narcotic Antagonist Analgesics by the Narcotic Antagonist Naloxone

open access: yesExperimental Biology and Medicine, 1966
SummaryWhen the potent narcotic antagonist, naloxone, was injected subcutane-ously into mice and rats simultaneously with narcotic antagonist analgesics, naloxone counteracted the writhing test analgesic activity of the antagonists. Naloxone completely antagonized the potent analgesic activity of pentazocine, nalorphine, cyclazocine, and cy-clorphan ...
Harold Blumberg   +2 more
openaire   +3 more sources

Beyond “Making Poland Great Again.” Nostalgia in Polish Populist and Non‐populist Discourses1

open access: yesSociological Forum, Volume 37, Issue S1, Page 1360-1386, December 2022., 2022
Nostalgia can be triggered not only by personal recollections but also by exposure to narratives or images evoking desirable pasts, more or less fictional, and inducing feelings of longing for them. We analyze the institutional and semiotic machinery involved in the cultural construction of nostalgia in Poland and its role in generating sentiments that
Marta Kotwas, Jan Kubik
wiley   +1 more source

Interactions of narcotic antagonists and antagonist-analgesics

open access: yesJournal of Pharmacy and Pharmacology, 1968
Abstract In the rat the potent narcotic antagonist N-cyclopropylmethyl-6,14-endoethano-7α- (1-hydroxy-1-methylethyl)-tetrahydronororipavine (M5050, Reckitt), which itself lacks analgesic activity, resembled naloxone in its capacity to reverse the antinociceptive effects of morphine antagonist-analgesics. The nociceptive stimulus employed
G F Blane, D Dugdall
openaire   +3 more sources

Opioid stimulation in the ventral tegmental area facilitates the onset of maternal behavior in rats [PDF]

open access: yes, 1996
This research investigated the effect of an increase or decrease in opioid activity in the ventral tegmental area (VTA) on the onset of maternal behavior in rats.
Kristal, Mark B., Thompson, Alexis C.
core   +1 more source

Central and peripheral mechanisms of narcotic antitussives: codeine-sensitive and -resistant coughs [PDF]

open access: yes, 2007
Narcotic antitussives such as codeine reveal the antitussive effect primarily via the μ-opioid receptor in the central nervous system (CNS). The κ-opioid receptor also seems to contribute partly to the production of the antitussive effect of the drugs ...
Shirasaki, Tetsuya, Takahama, Kazuo
core   +2 more sources

Selective review and commentary on emerging pharmacotherapies for opioid addiction. [PDF]

open access: yes, 2011
Pharmacotherapies for opioid addiction under active development in the US include lofexidine (primarily for managing withdrawal symptoms) and Probuphine®, a distinctive mode of delivering buprenorphine for six months, thus relieving patients, clinicians,
Ling, Walter   +5 more
core   +2 more sources

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