Results 21 to 30 of about 13,200 (250)

Interactions of narcotic antagonists and antagonist-analgesics

Journal of Pharmacy and Pharmacology, 1968
Abstract In the rat the potent narcotic antagonist N-cyclopropylmethyl-6,14-endoethano-7α- (1-hydroxy-1-methylethyl)-tetrahydronororipavine (M5050, Reckitt), which itself lacks analgesic activity, resembled naloxone in its capacity to reverse the antinociceptive effects of morphine antagonist-analgesics. The nociceptive stimulus employed
G F, Blane, D, Dugdall
openaire   +2 more sources

Evaluation of butorphanol, medetomidine and midazolam as a reversible narcotic combination in free-ranging African lions (Panthera leo) [PDF]

, 2010
Objective To evaluate the effects of the combination butorphanol, medetomidine and midazolam (BMM) and its reversibility in lions. Study design Prospective clinical trial.
Bush, Caulkett, Fahlman, Fleming, Fukuda, Gunkel, Haigh, Hall, Handler, Herbst, Ilkiw, Jacquier, Jean-Michel Hatt, Jenny Joubert, Johan Steenkamp, Kalema-Zikusoka, King, King, King, Kock, Lafortune, Larsen, Lemke, McKenzie, Pang, Peter Buss, Purvance Shikwambana, Pypendop, Pypendop, Quandt, Sandra Wenger, Smuts, Spelman, Stander, Tomizawa, Verstegen, Walzer, Williams   +37 more
core   +1 more source

Methods of forensic examination of Nalbuphine

Bulletin of Kharkiv National University of Internal Affairs
The article discusses the peculiarities of forensic examination of nalbuphine hydrochloride, a prescription medicine that can be purchased without a prescription in many pharmacies.
I. О. Besedina
doaj   +1 more source

Nonsteroidal Anti‐Inflammatory Drugs and Risk of Gastrointestinal Bleeding: A Systematic Review and Meta‐Analysis

Clinical Pharmacology &Therapeutics, EarlyView.
Nonsteroidal anti‐inflammatory drugs (NSAIDs) are widely used for pain and inflammation but are associated with gastrointestinal (GI) bleeding. While this risk is well established, most studies evaluate NSAIDs as a homogenous class, limiting clinical decision‐making based on individual agent safety.
Abdelrahman G. Tawfik, Ainhoa Gomez‐Lumbreras, Guilherme Del Fiol, Kensaku Kawamoto, Katy E. Trinkley, Thomas Reese, Aubrey Jones, Daniel C. Malone   +7 more
wiley   +1 more source

The Efficacy of Peripheral Opioid Antagonists in Opioid-Induced Constipation and Postoperative Ileus: A Systematic Review of the Literature. [PDF]

, 2017
Opioid-induced constipation has a negative impact on quality of life for patients with chronic pain and can affect more than a third of patients. A related but separate entity is postoperative ileus, which is an abnormal pattern of gastrointestinal ...
Baratta, Jaime L., Grant, Alexander E., McNulty, Stephen E., Schwenk, Eric S., Torjman, Marc C., Viscusi, Eugene R.   +5 more
core   +1 more source

Long-acting κ opioid antagonists nor-BNI, GNTI and JDTic: pharmacokinetics in mice and lipophilicity [PDF]

, 2012
Background: Nor-BNI, GNTI and JDTic induce κ opioid antagonism that is delayed by hours and can persist for months. Other effects are transient. It has been proposed that these drugs may be slowly absorbed or distributed, and may dissolve in cell ...
Beguin, Cecile Andree, Berry, Loren M, Carlezon, William A., Carroll, F Ivy, Cohen, Bruce Michael, Munro, Thomas A, Van't Veer, Ashlee Victoria, Zhao, Zhiyang   +7 more
core   +1 more source

Reimagining Urban River Bathing in Europe: A Multisectoral and Interdisciplinary Dive Into Lyon's Rivers (France)

River Research and Applications, EarlyView.
ABSTRACT Urban river bathing is re‐emerging across Europe, driven by social demand and climate change impacts. The Urban Bathing Consortium, an interdisciplinary and intersectoral consortium initiated at the University of Lyon (France), is at the forefront of studying the challenges and opportunities of creating and managing healthy, safe, and ...
Yixin Cao, Patrice Barbiero, François Briat, Benoit Camenen, Frédéric Chambat, Victoria Chiu, Benoit Cournoyer, Magali Delavenne, Benjamin Dewals, Marie Epain, Anne Honegger, Jérôme Le Coz, Gislain Lipeme Kouyi, Célia Maghakian, Oldrich Navratil, Olivier Pillonel, Marion Porcherie, Sara Puijalon, Nicolas Riviere, Marie‐Florence Thomas, Richard Trillat, Laurence Volatier, Jean‐Marie Zanot   +22 more
wiley   +1 more source

Former heroin-dependent alcohol use disorder patients. prevalence, addiction history and clinical features [PDF]

, 2015
Aims: To examine the prevalence of former heroin dependence (FHA) in Alcohol Use Disorder (AUD) patients; to compare the clinical characteristics of FHA-AUD patients versus AUD patients without any past use of heroin at alcohol treatment entry; to ...
Ceccanti, Mauro, Maremmani, Angelo Giovanni Icro, Maremmani, Icro, Pacini, Matteo   +3 more
core   +1 more source

How Trump Gets on Our Nerves

The Political Quarterly, EarlyView.
Abstract Public opinion polling has found that responses to the second presidency of Donald Trump range from the exuberant enthusiasm of his followers to anxiety, stress and anger, not only amongst many US citizens, but also a large section of the world's population who did not vote for him but are affected by his policies and governing style.
STEPHEN COLEMAN
wiley   +1 more source

Nitrous Oxide: Mechanism of Its Antinociceptive Action [PDF]

, 1995
Nitrous oxide (N2O) is an anesthetic gas known to produce an analgesic effect at sub-anesthetic concentrations. This analgesic property of N2O can be clinically exploited in a broad range of conditions where pain relief is indicated.
Quock, Raymond M., Vaughn, Linda K.
core   +1 more source