Selective review and commentary on emerging pharmacotherapies for opioid addiction. [PDF]
Pharmacotherapies for opioid addiction under active development in the US include lofexidine (primarily for managing withdrawal symptoms) and Probuphine®, a distinctive mode of delivering buprenorphine for six months, thus relieving patients, clinicians,
Ling, Walter +5 more
core +2 more sources
Can enhanced street lighting improve public safety at scale?
Abstract Research Summary Street crimes are thought to be influenced by changes in ambient lighting; yet, most studies have focused on small‐scale interventions in limited areas. It remains unclear whether enhanced lighting can improve safety on a larger, jurisdiction‐wide scale.
John M. MacDonald +6 more
wiley +1 more source
Amniotic-Fluid Ingestion Enhances\ud Morphine Analgesia During Morphine\ud Tolerance and Withdrawal in Rats [PDF]
Ingestion of placenta and amniotic fluid has been shown to enhance opioid-mediated analgesia in rats produced by morphine injection. footshock, vaginal/cervical stimulation, and during late pregnancy.
Doerr, Jean C., Kristal, Dr. Mark B.
core
Memantine increases NMDA receptor level in the prefrontal cortex but fails to reverse apomorphine-induced conditioned place preference in rats [PDF]
Studies have shown that inflammation and neurodegeneration may accompany the development of addiction to apomorphine and that the glutamate NMDA receptor antagonist, memantine, may be neuroprotective.
Baxter BL, Gluckman MI, Stein L, et al. +26 more
core +2 more sources
Drug use among people in prison: A global review of epidemiology, harms and interventions
Abstract Background and aims People who use drugs are overrepresented in the criminal justice system. We aimed to provide a broad synthesis of the epidemiology, harms and interventions related to drug use and drug use disorders among incarcerated adults worldwide, and highlight gaps in evidence and practice.
Louis Favril, John Strang, Seena Fazel
wiley +1 more source
Flexor Reflex Decreases during Sympathetic Stimulation in Chronic Human Spinal Cord Injury [PDF]
A better understanding of autonomic influence on motor reflex pathways in spinal cord injury is important to the clinical management of autonomic dysreflexia and spasticity in spinal cord injured patients.
Garrison, Mark Kevin, Schmit, Brian D.
core +2 more sources
Assisted vaginal birth is a risk factor for perineal wound complication. This review was limited by a paucity of existing research in the area; therefore, further robust and well‐powered primary research is required. Created in BioRender. Man, R. (2025) https://BioRender.com/3zsekbj.
Rebecca Man +15 more
wiley +1 more source
Amniotic-Fluid Ingestion Enhances the Central\ud Analgesic Effect of Morphine [PDF]
Amniotic fluid and placenta contain a substance (POEF) that when ingested enhances opioid-mediated analgesia produced by several agents (morphine injection, vaginal/cervical stimulation, late pregnancy, footshock), but not that produced by aspirin ...
DiPirro, Jean M. +2 more
core
The analgesic effects of anti-inflammatory drugs from the point of view of different pharmacological test methods [PDF]
1. The forms of irritation causing inflammation and pain are reviewed, with reference to the significance of histamine, serotonin and bradykinin and in particular to the interrelationship between inflammation and pain. 2.
Wilhelmi, G.
core +1 more source
Transverse placement of electrical muscle stimulation (EMS) electrodes across muscle fibers elicits localized contractions, facilitating greater active stretching (AS) of regions containing myofascial trigger points. This EMS + AS approach mimics passive stretching, with EMS providing resistance force similar to that typically applied by a therapist's ...
Seekaow Churproong +3 more
wiley +1 more source

