Results 21 to 30 of about 4,273 (205)

Antifungal Combination Eye Drops for Fungal Keratitis Treatment

Pharmaceutics, 2022
Fungal keratitis (FK) is a corneal mycotic infection that can lead to vision loss. Furthermore, the severity of FK is aggravated by the emergence of resistant fungal species.
Victoria Díaz-Tomé, Carlos Bendicho-Lavilla, Xurxo García-Otero, Rubén Varela-Fernández, Manuel Martín-Pastor, José Llovo-Taboada, Pilar Alonso-Alonso, Pablo Aguiar, Miguel González-Barcia, Anxo Fernández-Ferreiro, Francisco J. Otero-Espinar   +10 more
doaj   +1 more source

Natamycin versus natamycin combined with voriconazole in the treatment of fungal keratitis

Pakistan Journal of Medical Sciences, 2023
Objective: To observe the therapeutic effect of natamycin combined with voriconazole in the treatment of fungal keratitis (FK). Methods: This is a retrospective study. The subjects of this study were 64 patients with FK who were admitted to Baoding No.1 Central Hospital from February 2019 to July 2022.
Cai, Jingjing, Yang, Chengwen, Wei, Qiuhong, Lian, Huifang, An, Lin, Zhang, Rong   +5 more
openaire   +2 more sources

Evaluation of antifungal susceptibility and clinical characteristics in fungal keratitis in a tertiary care center in North India

Indian Journal of Ophthalmology, 2022
Purpose: To study the antifungal susceptibility of common corneal pathogenic fungi to antifungal agents in the North Indian population. Methods: Prospective study of the antifungal sensitivity testing (natamycin, amphotericin B, voriconazole ...
Murugesan Vanathi, Ravinder Naik, Navneet Sidhu, Nishat Hussain Ahmed, Noopur Gupta, Radhika Tandon   +5 more
doaj   +1 more source

Natamycin sequesters ergosterol and interferes with substrate transport by the lysine transporter Lyp1 from yeast [PDF]

, 2022
Natamycin is a polyene macrolide, widely employed to treat fungal keratitis and other yeast infections as well as to protect food products against fungal molds.
Holger A. Scheidt, Wüstner, Daniel; id_orcid, Sebastian Obermaier, Reinholdt, Peter; id_orcid, Scheidt, Holger A., Hanna-Loisa Walther, Walther, Hanna Loisa, Daniel Wüstner, Wüstner, Daniel, Bert Poolman, Kongsted, Jacob; id_orcid, Poolman, Bert, Obermaier, Sebastian; id_orcid, Kongsted, Jacob, Müller, Peter, Jacob Kongsted, Obermaier, Sebastian, Maria Szomek, Peter Reinholdt, Peter Müller, Reinholdt, Peter, Szomek, Maria   +21 more
core   +1 more source

Corn starch-based coating enriched with natamycin as an active compound to control mold contamination on semi-hard cheese during ripening

Heliyon, 2019
The effectiveness of natamycin supported in corn starch-based films to control environmental molds (mainly Penicillium spp) activity that could colonize the surface of semi-hard cheese during ripening, was evaluated.
Lucía del Sol González-Forte, Javier I. Amalvy, Nora Bertola   +2 more
doaj   +1 more source

The investigation of microbial contamination and Natamycin in industrial Dough produced in Ardabil [PDF]

Bihdāsht-i Mavādd-i Ghaz̠āyī, 2020
Natamycin is a preservative used to control molds and yeast in dough; however, the Food and Drug Administration prohibits the use of any preservative in the production of dough.
N Soheili, Ramin Atazadeh, Azadeh Jodaie
doaj   +1 more source

Enhanced Natamycin production by Streptomyces natalensis in shake-flasks and stirred tank bioreactor under batch and fed-batch conditions

BMC Biotechnology, 2019
Background Natamycin is an antifungal polyene macrolide antibiotic with wide applications in health and food industries. Currently, it is the only antifungal food additive with the GRAS status (Generally Regarded as Safe).
Elsayed Ahmed Elsayed, Mohamed A. Farid, Hesham A. El-Enshasy   +2 more
doaj   +1 more source

Scientific Opinion on the use of natamycin (E 235) as a food additive

EFSA Journal, 2009
Following a request from the European Commission to EFSA, the Scientific Panel on Food Additives and Nutrient Sources added to Food (ANS) was asked to provide a scientific opinion on the safety in use of natamycin (E 235) as a food additive, and on the ...
EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS)
doaj   +1 more source

Natamycin inhibits vacuole fusion at the priming phase via a specific interaction with ergosterol

, 2010
The antifungal antibiotic natamycin belongs to the family of polyene antibiotics. Its antifungal activity arises via a specific interaction with ergosterol in the plasma membrane (te Welscher et al., J. Biol. Chem. 283:6393-6401, 2008).
van Leeuwen, M.R., Dijksterhuis, J., te Welscher, Y.M., de Kruijff, B., Breukink, E.J., Sub Algemeen Scheikunde, Sub Biochemistry of Membranes begr1-6-12, Molecular Microbiology, Sub Molecular Microbiology, Jones, L., Eitzen, G., te Welsher, Y.M., Biochemistry of membranes   +12 more
core   +1 more source

Effect of natamycin on cytochrome P450 enzymes in rats

, 2013
Natamycin is a polyene macrolide antibiotic widely used in the food industry as a feed additive to prevent mold contamination of foods. There are many contradictory results on the genotoxic effects of macrolides which could suggest a potential risk for ...
Romero Martínez, Manuel Alejandro, Martínez Caballero, Marta, Martínez Caballero, María Aranzazu, Anadón Navarro, Arturo Ramón, Castellano Santos, Víctor Jesús, Martínez Larrañaga, María Rosa, Ares Lombán, Irma   +6 more
core   +1 more source