Molecular Implications of natriuretic peptides in the protection from hypertension and target organ damage development [PDF]
, 2019 The pathogenesis of hypertension, as a multifactorial trait, is complex. High blood pressure levels, in turn, concur with the development of cardiovascular damage.
Forte, Maurizio +3 more
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Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022 Background Contemporary guidelines recommend using atherosclerotic cardiovascular disease screening tools to guide primary prevention. The performance of these scores is not well known in patients with moderate to advanced chronic kidney disease ...
Benjamin Lidgard +4 more
doaj +1 more source
Biomarker Prediktor Kejadian Poliuria pada Resipien Pascatransplantasi Ginjal [PDF]
, 2015 Poliuria pada resipien pascatransplantasi ginjal merupakan kondisi yang sering terjadi dan berpotensi menimbulkan komplikasi fatal apabila berlangsung secara masif, terus menerus, dan tanpa pengawasanyang ketat.
Rodjani, A. (Arry) +1 more
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C-type natriuretic peptide moderates titin-based cardiomyocyte stiffness
JCI Insight, 2020 Heart failure is often accompanied by titin-dependent myocardial stiffness. Phosphorylation of titin by cGMP-dependent protein kinase I (PKGI) increases cardiomyocyte distensibility.
Konstanze Michel +11 more
doaj +1 more source
La alteración de sistemas natriuréticos renales se asocia con el desarrollo de hipertensión arterial y precede en el tiempo a la aparición de daño renal en un modelo de síndrome metabólico [PDF]
, 2018 Objetivos: El objetivo del trabajo consistió en determinar la existencia de alteraciones en los sistemas natriuréticos del péptido natriurético atrial y dopamina renal en un modelo de síndrome metabólico por sobrecarga de fructosa y asociarlas con ...
Choi, Marcelo Roberto +7 more
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The oocyte cumulus complex regulates mouse sperm migration in the oviduct
Communications Biology, 2022 Oocyte-dependent and cumulus cell-derived transforming growth factor-β promotes natriuretic peptide type C expression in mouse ampullary epithelial cells, which promotes sperm migration into the ampulla for fertilization.
Zhijuan Wang +8 more
doaj +1 more source
C-type natriuretic peptide and vascular remodeling
Journal of the American College of Cardiology, 2001 Morishige et al. [(1)][1]have reported local adenovirus-mediated transfer of C-type natriuretic peptide (CNP) to porcine coronary arteries, resulting in reduced stenosis of balloon-injured segments. This is an exciting development with obvious therapeutic potential.
Davidson, Neil C, Struthers, A D
openaire +3 more sources
Detection of C-type natriuretic peptide (CNP) transcript in the rat heart and immune organs [PDF]
, 1993 Previous studies suggested the expression of mRNA, coding for CNP, exclusively in the central nervous system. In the present study, using the polymerase chain reaction (PCR) technique instead of the less sensitive Northern blot hybridization, CNP ...
Gerbes, Alexander L. +3 more
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Regulation of C-type natriuretic peptide expression
Peptides, 2011 C-type natriuretic peptide (CNP) is a member of the small family of natriuretic peptides that also includes atrial natriuretic peptide (ANP) and brain, or B-type natriuretic peptide (BNP). Unlike them, it performs its major functions in an autocrine or paracrine manner.
Sellitti, Donald F. +2 more
openaire +4 more sources
Natriuretic peptides and cardiovascular damage in the metabolic syndrome. Molecular mechanisms and clinical implications [PDF]
, 2010 Natriuretic peptides are endogenous antagonists of vasoconstrictor and salt- and water-retaining systems in the body's defence against blood pressure elevation and plasma volume expansion, through direct vasodilator, diuretic and natriuretic properties ...
ALONZO, ALESSANDRO +4 more
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