Results 61 to 70 of about 105,569 (311)

Prognostic value of biomarkers in chronic heart failure with preserved left ventricular ejection fraction [PDF]

Терапевтический архив, 2016
The paper reviews major biomarkers for determining the prognosis in patients with chronic heart failure and preserved ejection fraction. It also considers cystatin C, one of the novel and probably the most practically important biomarkers.
T A Nikiforova, D Yu Shchekochikhin, F Yu Kopylov, A L Syrkin   +3 more
doaj   +1 more source

C-type natriuretic peptide (CNP) in the paraventricular nucleus-mediated renal sympatho-inhibition

Frontiers in Physiology, 2023
Volume reflex produces sympatho-inhibition that is mediated by the hypothalamic paraventricular nucleus (PVN). However, the mechanisms for the sympatho-inhibitory role of the PVN and the neurochemical factors involved remain to be identified.
Hong Zheng, Tapan A. Patel, Xuefei Liu, Kaushik P. Patel   +3 more
doaj   +1 more source

N-Terminal Pro–B-Type Natriuretic Peptide in the Emergency Department: The ICON-RELOADED Study [PDF]

, 2018
Background Contemporary reconsideration of diagnostic N-terminal pro–B-type natriuretic peptide (NT-proBNP) cutoffs for diagnosis of heart failure (HF) is needed.
Chen-Tournoux, Annabel A., Christenson, Robert H., Doros, Gheorghe, Gaggin, Hanna K., Hollander, Judd E., Januzzi, James L., Levy, Phillip D., Nagurney, John T., Nowak, Richard M., Pang, Peter S., Patel, Darshita, Peacock, W. Franklin, Rivers, E. Joy, Walters, Elizabeth L.   +13 more
core   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Discrimination and Quantification of Glomerular Receptor Subtypes for Atrial Natriuretic Factor (Anf) [PDF]

, 1991
Binding sites for atrial natriuretic factor (ANF) were determined on isolated rat glomeruli as well as on glomerular membranes. To define optimal conditions, binding of ANF was investigated varying incubation time, temperature and protein concentration ...
Gerbes, Alexander L., Kollenda, Margit C., Scarborough, Robert M.   +2 more
core   +1 more source

Marine silicon for biomedical sustainability

BMEMat, EarlyView.
Schematic illustrating marine silicon for biomedical engineering. Abstract Despite momentous divergence from oceanic origin, human beings and marine organisms exhibit elemental homology through silicon utilization. Notably, silicon serves as a critical constituent in multiple biomedical processes.
Yahui Han, Zhibo Yang, Wei Xia, Chengtie Wu   +3 more
wiley   +1 more source

Predicting Coronary Occlusion Risk during Redo‐TAVR at First TAVR: Asymmetric Calcification Causes Failure

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background and Aims Predicting coronary artery occlusion due to sinus sequestration (SS) during a second transcatheter aortic valve (TAV) procedure using pre‐procedural computed tomography (CT) after the first TAV replacement (TAVR) is underreported.
Kyohei Onishi, Masakazu Yasuda, Nobuhiro Yamada, Naoko Soejima, Ayano Yoshida, Kosuke Fujita, Hiroki Matsuzoe, Tatsuya Miyoshi, Koichiro Matsumura, Kazuki Mizutani, Masafumi Ueno, Genichi Sakaguchi, Gaku Nakazawa   +12 more
wiley   +1 more source

The significance of natriuretic peptides in the evaluation of water-salt metabolism in chronic kidney disease

Терапевтический архив, 2014
The paper discusses the molecular, biochemical, and physiological properties of natriuretic peptides, including the clinical applications of their synthetic formulations, as well as the renal and extrarenal mechanisms of water-salt metabolism in chronic ...
A A Pulin, T Iu Kustova, V V Fomin, N A Mukhin   +3 more
doaj  

Once-weekly TransCon CNP (navepegritide) in children with achondroplasia (ACcomplisH): a phase 2, multicentre, randomised, double-blind, placebo-controlled, dose-escalation trialResearch in context

EClinicalMedicine, 2023
Summary: Background: TransCon CNP (navepegritide) is an investigational prodrug of C-type natriuretic peptide (CNP) designed to allow for continuous CNP exposure with once-weekly dosing.
Ravi Savarirayan, Daniel G. Hoernschemeyer, Merete Ljungberg, Yuri A. Zarate, Carlos A. Bacino, Michael B. Bober, Janet M. Legare, Wolfgang Högler, Teresa Quattrin, M. Jennifer Abuzzahab, Paul L. Hofman, Klane K. White, Nina S. Ma, Dirk Schnabel, Sérgio B. Sousa, Meng Mao, Alden Smith, Mukta Chakraborty, Adebola Giwa, Bent Winding, Birgitte Volck, Aimee D. Shu, Ciara McDonnell   +22 more
doaj   +1 more source

Noninvasive imaging of focal atherosclerotic lesions using fluorescence molecular tomography [PDF]

, 2014
Insights into the etiology of stroke and myocardial infarction suggest that rupture of unstable atherosclerotic plaque is the precipitating event. Clinicians lack tools to detect lesion instability early enough to intervene, and are often left to manage ...
Abendschein, Dana R., Achilefu, Samuel, Akers, Walter J., Culver, Joseph P., Maji, Dolonchampa, Nguyen, Annie, Pierce, Richard A., Shokeen, Monica, Solomon, Metasebya, Woodard, Pamela K.   +9 more
core   +2 more sources