Results 261 to 270 of about 664,837 (368)

HIC1 suppresses Tumor Progression and Enhances CD8+ T Cells Infiltration Through Promoting GSDMD‐induced Pyroptosis in Gastric Cancer

Advanced Science, EarlyView.
These findings elucidate the innovative role of HIC1 as a transcriptional activator in GC, driving the initiation of pyroptosis and enhancing CD8+ T cell infiltration, which has certain novelty and creative significance. Collectively, targeting HIC1 can present an appealing immunotherapeutic strategy to improve outcomes in GC patients.
Mengjie Kang, Wenqi Du, Lina Ding, Mengdi Wu, Dongsheng Pei   +4 more
wiley   +1 more source

Inability of interferon to protect virus-infected cells against lysis by natural killer (NK) cells correlates with NK cell-mediated antiviral effects in vivo. [PDF]

, 1985
Jack F. Bukowski, Raymond M. Welsh
openalex   +1 more source

Natural killer cells' functional impairment drives the immune escape of pre-malignant clones in early-stage myelodysplastic syndromes. [PDF]

Nat Commun
Rodriguez-Sevilla JJ, Ganan-Gomez I, Kumar B, Thongon N, Ma F, Chien KS, Kim YJ, Yang H, Loghavi S, Tan R, Adema V, Li Z, Tanaka T, Uryu H, Kanagal-Shamanna R, Al-Atrash G, Bejar R, Banerjee PP, Lynn Cha S, Montalban-Bravo G, Dougherty M, Fernandez Laurita MC, Wheeler N, Jia B, Papapetrou EP, Izzo F, Dueñas DE, McAllen S, Gu Y, Todisco G, Ficara F, Della Porta MG, Jain A, Takahashi K, Clise-Dwyer K, Halene S, Bertilaccio MTS, Garcia-Manero G, Daher M, Colla S.   +39 more
europepmc   +1 more source

Microneedles at the Forefront of Next Generation Theranostics

Advanced Science, EarlyView.
The TOC figure illustrates the revolutionary role of microneedles in modern medicine, showcasing their dual diagnostic and therapeutic functions. On the left, microneedles access interstitial fluid for real‐time monitoring of biomarkers like glucose and hormones.
Chan Wang, Yuan Yang, Jiaqi Zhang, Hanrui Zhang, Qian Wang, Shengmei Ma, Pengfei Zhao, Zhou Li, Yuxin Liu   +8 more
wiley   +1 more source

Sr++-induced inhibition of human natural killer (NK) cell-mediated cytotoxicity. [PDF]

, 1982
P. Andrew Neighbour, Harris S. Huberman
openalex   +1 more source

Distinct immunity dynamics of natural killer cells in mild and moderate COVID-19 cases during the Omicron variant phase. [PDF]

Front Immunol
Nishikawa Y, Yamaguchi K, Shofiudin MA, Mimura M, Takata M, Mihara S, Kawakami T, Doi A, Matsuda R, Kato H, Okamoto R, Mukuda K, Kinoshita N, Okada K, Kitaura T, Nakamoto M, Noma H, Endo Y, Yamasaki A, Chikumi H.   +19 more
europepmc   +1 more source

IncRNA‐ZFAS1, an Emerging Gate‐Keeper in DNA Damage‐Dependent Transcriptional Regulation

Advanced Science, EarlyView.
LncZFAS1 plays a crucial role during DNA damage response in mammalian cells. Loss of lncZFAS1 results in deficient DNA lesion removal and reduced cell viability. Mechanistically, lncZFAS1 modulates RNAPII phosphorylation and transcription and thereby promotes both GG‐NER and TC‐NER upon UV damage.
Jiena Liu, Qing Lu, Zixuan Fan, Jiahui Lin, Nan He, Xin Zhang, Zhaoya Han, Tingting Zhu, Zhenzhen Wu, Yingying Xu, Yuming Wang   +10 more
wiley   +1 more source

Studies of rheumatoid synovial fluid lymphocytes. I. Evidence for activated natural killer- (NK) like cells. [PDF]

, 1982
Richard M. Silver, Doug Redelman, Nathan J. Zvaifler, Stanley J. Naides   +3 more
openalex   +1 more source

Emerging Insights into Memory Natural Killer Cells and Clinical Applications. [PDF]

Viruses
Kokiçi J, Preechanukul A, Arellano-Ballestero H, Gorou F, Peppa D.   +4 more
europepmc   +1 more source

Zonated Copper‐Driven Breast Cancer Progression Countered by a Copper‐Depleting Nanoagent for Immune and Metabolic Reprogramming

Advanced Science, Volume 12, Issue 20, May 29, 2025.
Spatially resolved multiomics reveals that high‐copper zones are closely associated with tumor metastasis, immune‐desert phenotypes, and oxidative‐phosphorylation (OXPHOS)‐dependent proliferation. A targeted bacterial nanovesicle delivering copper‐depleting agents effectively reduces tumor copper levels, inhibits OXPHOS‐dependent tumor growth, and ...
Lin Chen, Saibo Ma, Hao Wu, Lingna Zheng, Yunpeng Yi, Guangnian Liu, Baoyi Li, Jiayi Sun, Yang Du, Bing Wang, Yike Liu, Cheng Zhang, Jing Chang, Yuheng Pang, Wenjing Wang, Meng Wang, Motao Zhu   +16 more
wiley   +1 more source