Results 231 to 240 of about 247,672 (311)

Dumbbell‐Structured Plasmonic‐Enhanced Optical Nanoprobes Boosting Photo‐Magnetic‐Acoustic Multimodal Imaging‐Guided Photodynamic‐Photothermal Synergistic Treatment and Immunogenic Death in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
This study reports a novel rationally‐designed optical nanoprobe based on dumbbell‐shaped mesoporous silica‐coated gold nanorods, loaded with rare‐earth oxides, photosensitizers, and tumor‐targeted peptides, enabling plasmonic‐enhanced multimodal imaging and PTT‐PDT synergy.
Baikang Zhuang, Yubiao Yang, Wen Han, Yi Tang, Chengxin Yao, Fuli Zhao, Wenxiao Fang, Jinjie Li, Xiaolan Huo, Yiqian An, Yuanzhi Shao, Botao Gao, Jinchang Yin   +12 more
wiley   +1 more source

Antibody-Dependent Cellular Cytotoxicity of iPS Cell-Derived Natural Killer T Cells by Anti-GD2 mAb for Neuroblastoma. [PDF]

Cancer Sci
Nishimura K, Aoki T, Kobayashi M, Takami M, Ozaki K, Ogawa K, Hongxuan W, Shimizu D, Katsumi D, Yoshizawa H, Komatsu S, Takatani T, Hirahara K, Koseki H, Hishiki T, Motohashi S.   +15 more
europepmc   +1 more source

Engineering Oncolytic Virus‐Armed Macrophages for Enhanced Cancer Immunotherapy

Advanced Science, EarlyView.
ZIFOA‐M is engineered by conjugating oncolytic adenovirus‐loaded ZIF‐8 nanoparticles onto macrophage surfaces via bioorthogonal chemistry. Upon tumor infiltration, the platform releases OA to downregulate CD47/CD24 on tumor cells, restoring macrophage phagocytosis.
Jilong Wang, Ning Lu, Zhuo Yan, Luyi Ye, Luyao Bai, Shanshan Yuan, Yuting Zhu, Yiru Xiong, Yongheng Bai, Yaping Chen, Junjie Deng   +10 more
wiley   +1 more source

Promising Cellular Immunotherapy for Colorectal Cancer Using Classical Dendritic Cells and Natural Killer T Cells. [PDF]

Cells
Singer M, Valerin J, Zhang Z, Zhang Z, Dayyani F, Yaghmai V, Choi A, Imagawa D, Abi-Jaoudeh N.   +8 more
europepmc   +1 more source

A Novel Approach Based on Acceptor–Donor–Acceptor Type Molecules Enhances the Therapeutic Efficacy and Safety of Photothermal Therapy for Osteosarcoma

Advanced Science, EarlyView.
Jin et al. developed IEICO‐F nanoparticles with enhanced photothermal conversion efficiency via optimized push‐pull effect. Under 808 nm laser, these nanoparticles effectively generated heat to kill osteosarcoma cells and exhibited significant tumor suppression in vivo. Therefore, this novel A‐D‐A type molecule‐based photothermal therapy strategy holds
Zhijian Jin, Hongru Wang, Yi Yang, Yuhang Xie, Yuan Zhang, Zhiye Du, Yi Huang, Wei Guo, Yang Li, Shidong Wang   +9 more
wiley   +1 more source

Can invariant Natural Killer T cells drive B cell fate? a look at the humoral response. [PDF]

Front Immunol
Palacios PA, Santibañez Á, Aguirre-Muñoz F, Gutiérrez-Vera C, Niño de Zepeda-Carrizo V, Góngora-Pimentel M, Müller M, Cáceres M, Kalergis AM, Carreño LJ.   +9 more
europepmc   +1 more source

Genetic Code Expanded T Cell for Controllable Immunotherapy

Advanced Science, EarlyView.
Our GCE‐CAR‐T cells enables tight, dose‐dependent, and function‐preserving control of CAR expression at the translational level through amber codon suppression and genetic incorporation of ncAA. ABSTRACT Chimeric antigen receptor (CAR)‐T cell therapy has demonstrated curative potential against hematologic malignancies, but its clinical application ...
Xue Wang, Yingao Gao, Yeyu Su, Yong Wang, Tao Liu   +4 more
wiley   +1 more source

Distinct T Cell Receptor Clonotypes in the Sardinian Population Highlight the Role of Mucosal-Associated Invariant T Cells and Invariant Natural Killer T Cells in Multiple Sclerosis. [PDF]

Immunology
Shen J, Simula ER, Liu Y, Sganzerla Martinez G, Wen X, Kelvin DJ, Sechi LA.   +6 more
europepmc   +1 more source

Pathogen‐Centric Activation of an Azoreductase‐Responsive Antibody‐Antibiotic Conjugate for the Targeted Eradication of MRSA

Advanced Science, EarlyView.
A pathogen‐centric antibody‐antibiotic conjugate (AZO‐AAC) releases antibiotics via bacterial azoreductase, independent of host‐lysosomal function. This mechanism achieves nanomolar eradication of both planktonic and intracellular methicillin‐resistant Staphylococcus aureus (MRSA).
Qi Cheng, Lianqi Liu, Chenghua Liu, Fei Xie, Jingwen Dong, Xiaoyu Qin, Shunxiang Huang, Xian Li, Xingyuan Kou, Hongbin Deng, Jiannan Feng, Wu Zhong, Dian Xiao, Xinbo Zhou   +13 more
wiley   +1 more source

The Absence of Thyroid-Stimulating Hormone Receptor Expression on Natural Killer T Cells: Implications for the Immune-Endocrine Interaction. [PDF]

Int J Mol Sci
Adamska-Fita E, Śliwka PW, Karbownik-Lewińska M, Lewiński A, Stasiak M.   +4 more
europepmc   +1 more source