Results 211 to 220 of about 247,672 (311)

Natural killer T-cells in asthma pathogenesis and treatment: old problems and future perspectives. [PDF]

ERJ Open Res
Dilroba A, Fanella A, Pianigiani T, Paggi I, d'Alessandro M, Saletti M, Bargagli E, Cameli P, Bergantini L.   +8 more
europepmc   +1 more source

Bioorthogonal Fluorogenic Reporters for Noninvasive Imaging and Urinalysis of Immunotherapeutic Response in Renal Cell Carcinoma

Advanced Science, EarlyView.
This study reported renal‐clearable bio‐orthogonal near‐infrared fluorogenic probes (BGRs) that specifically imaging and urinalysis of granzyme B for dynamic evaluation of RCC immunotherapy. BGRs not only differentiate immunotherapeutic responses in orthotopic RCC mice, but also enable sensitive optical urinalysis of granzyme B in clinical specimens ...
Xingyue Yang, Baoshuai Liang, Liangmin Fu, Weiliang Deng, Yuyan Jiang, Weiping Xu, Jinwei Chen, Ya Zhou, Ke Wu, Jiaguo Huang   +9 more
wiley   +1 more source

Natural Killer T Cells Link Stress Hyperglycemia to Cognitive Decline in HFpEF. [PDF]

Circ Res
Mone P, Ciccarelli M, Jankauskas SS, Picone F, Guerra G, Testa G, Moccia F, Magliuolo R, Di Mauro M, De Luca A, Carrizzo A, Vecchione C, Santulli G.   +12 more
europepmc   +1 more source

Invariant natural killer T cells and incidence of first-time coronary events: a nested case-control study. [PDF]

Eur Heart J Open, 2023
Tomas L, Katra P, Badn W, Andersson L, Nilsson J, Schiopu A, Engelbertsen D, Gonçalves I, Bengtsson E, Björkbacka H.   +9 more
europepmc   +1 more source

A Hydrogen‐Releasing Nanozyme Engineers a Mitochondrial ROS Amplifier for Self‐Sustaining Catalytic Immunotherapy

Advanced Science, EarlyView.
We developed a RhPd‐H nanozyme that integrates enhanced POD‐mimetic catalytic activity with thermally triggered H2 release. H2 shields and reprograms mitochondria to continuously leak endogenous ·O2−. This dual‐path ROS spatially and temporally disrupts redox homeostasis, inducing persistent oxidative stress for tumor suppression and antitumor immunity,
Mingfan Shi, Jingrui Cao, Tong Wu, Guang Yang, YaWen Yang, Shixin Zhang, Wenwen Su, Hongyu Chu, Yangyang Zhao, Shan Jiang, Qiong Wu, Dongxu Jiao, Fangfang Chen   +12 more
wiley   +1 more source

Facts and Hopes of Chimeric Antigen Receptor-Redirected NK T Cells. [PDF]

Clin Cancer Res
Courtney AN, Zhou X, Tian G, Wang Y, Metelitsa LS, Dotti G.   +5 more
europepmc   +1 more source

Invariant natural killer T cells and iron metabolism orchestrate skin development and homeostasis. [PDF]

Cell Mol Immunol, 2023
Nabeshima H, Niitsu T, Fukushima K, Kida H.   +3 more
europepmc   +1 more source

tBid‐Mediated Genetic Ablation of Connective Tissue Cells Reveals Their Key Regulatory Function During Limb Regeneration in Axolotls

Advanced Science, EarlyView.
We establish a tBid‐mediated cell ablation system in axolotls, achieve rapid and efficient ablation of multiple cell types, including muscle stem cell, spinal cord cell, and connective tissue (CT) cells. We investigate the role of CT using tBid‐mediated CT ablation and identify its essential role for limb development and regeneration.
Yan Hu, Weimin Feng, Zitian He, Jiayi Zeng, Jingyi Tang, Shulin Li, Tongbo Yu, Sulei Fu, Hui Ma, Binbin Lu, Yanmei Liu, Ji‐Feng Fei   +11 more
wiley   +1 more source

Activation of Invariant Natural Killer T Cells Enhances Ischemia-Reperfusion Injury in Steatotic Mouse Livers. [PDF]

In Vivo
Kuroda YU, Ito Y, Nishizawa N, Tanabe M, Goto T, Yamashita A, Hosono K, Satoh M, Kumamoto Y, Hiki N, Amano H.   +10 more
europepmc   +1 more source

Targeting adrenergic receptors to mitigate invariant natural killer T cells-induced acute liver injury. [PDF]

iScience, 2023
Gonzatti MB, Freire BM, Antunes MM, de Menezes GB, Talbot J, Peron JPS, Basso AS, Keller AC.   +7 more
europepmc   +1 more source