Results 191 to 200 of about 247,672 (311)

Invariant Natural Killer T Cells in Cancer Immunotherapy: Lipid-Based Modulation, Nanotechnology, and Translational Advances. [PDF]

Int J Mol Sci
Aloliqi AA, Alnuqaydan AM, Alshebremi M, Khan A, Khan MA.   +4 more
europepmc   +1 more source

Tumor‐Intrinsic ARHGEF3 Enhances Antitumor Immunity by Promoting T‐Cell Infiltration and Limiting Myeloid Cell‐Mediated Immunosuppression

Advanced Science, EarlyView.
ARHGEF3 is broadly downregulated across human cancers and correlates with patient prognosis. Tumor‐intrinsic ARHGEF3 activates the RHOA–ROCK–PTEN cascade to inhibit AKT signaling, thereby promoting chemokine‐driven T‐cell infiltration and relieving lipid‐mediated myeloid immunosuppression.
Yue Li, Lan Wang, Zihao Zhang, Chunmei Qian, Ning Li, Wei Huang, Qian Ba, Xiaojian Liu, Mayu Sun   +8 more
wiley   +1 more source

Type 1 invariant natural killer T cells in chronic inflammation and tissue fibrosis. [PDF]

Front Immunol, 2023
Kumar V, Hertz M, Agro A, Byrne AJ.
europepmc   +1 more source

Oral Motion‐Powered Smart Dental Implant Abutment for In Situ Antibacterial and Cell Adhesion Through Piezoelectric Effect

Advanced Science, EarlyView.
We proposed a method based on the piezoelectric effect and fabricated an implant abutment on the basis of piezoelectric ceramic. Under physiological occlusal pressure, the oral motion‐powered smart dental implant abutments interacted with water and oxygen, promoting the formation of reactive oxygen species and achieving a synergistic and highly ...
Xiyu Shi, Xiaoyu Han, Yanhui Lu, Yuan Chai, Baiyan Xiao, Shuo Liu, Boon Chin Heng, Tingting Wu, Tingjun Li, Qiaomei Ren, Ting Song, Le Chen, Dong Han, Yaru Guo, Xuliang Deng, Xuehui Zhang   +15 more
wiley   +1 more source

Stem cell engineering for the generation of allogeneic CAR-directed natural killer T cells targeting endometrial carcinoma. [PDF]

Exp Hematol Oncol
Li YR, DiBernardo GA, Chen Y, Shen X, Hon R, Ruegg LE, Huang J, Neal A, Moatamed NA, Memarzadeh S, Yang L.   +10 more
europepmc   +1 more source

SPLENIC INVARIANT NATURAL KILLER T CELLS PLAY A SIGNIFICANT ROLE IN THE RESPONSE TO POLYMICROBIAL SEPSIS. [PDF]

Shock, 2023
Heffernan DS, Chung CS, Ayala A.
europepmc   +1 more source

Nanozymes for Advanced Hemoglobin‐Based Oxygen Carriers: Applications in Blood Substitution, Wound Healing, Antitumor Therapy, and Beyond

Advanced Science, EarlyView.
This review explores how hemoglobin‐based oxygen carriers (HBOCs) combined with nanozymes create multifunctional materials that deliver oxygen while maintaining redox homeostasis. Beyond artificial blood substitutes, these constructs enable wound healing with light‐triggered oxygen release, cancer therapy through enhanced oxygenation and reactive ...
Despoina Douka, Ana María Pablo‐Sainz‐Ezquerra, Eva Jakljevič, Niki Ktena, Leticia Hosta‐Rigau   +4 more
wiley   +1 more source

IL-18 metabolically reprograms CAR-expressing natural killer T cells and enhances their antitumor activity. [PDF]

Mol Ther
Barragán Bravo GA, de la Cerda DA, Landoni E, Dholakia K, Humeniuk P, Caraballo Galva LD, Wang Y, Tian G, Yang B, Guo L, Wood MS, Rios X, Xu X, Courtney AN, Di Pierro EJ, Jacob J, Li YH, Adaikkalavan A, Watanabe N, Mao S, Miles G, Dotti G, Metelitsa LS.   +22 more
europepmc   +1 more source

CD1d-Dependent Natural Killer T Cells Mediate Hypertension and Vascular Injury Through Interleukin-17A. [PDF]

J Am Heart Assoc, 2023
Xiao X, Hou CL, Zhang YL, Yang H, Wang XX, Wang HX.   +5 more
europepmc   +1 more source

Emerging role of Natural killer cells in oncolytic virotherapy

, 2015
Rauf Bhat, Jean Rommelaere Division of Tumor Virology, German Cancer Research Center, Heidelberg, Germany Abstract: Natural killer (NK) cells constitute a subtype of lymphocytes that initiate innate immune responses against tumors and virus-infected ...
Bhat R, Rommelaere J
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