Results 91 to 100 of about 323,886 (359)
Highly activated and expanded natural killer cells for multiple myeloma immunotherapy
Haematologica, 2012 Background Patients with gene expression profiling-defined high-risk myeloma in relapse have poor outcomes with current therapies. We tested whether natural killer cells expanded by co-culture with K562 cells transfected with 41BBL and membrane-bound ...
Tarun K. Garg +19 more
doaj +1 more source
The effect of blocking immune checkpoints LAG-3 and PD-1 on human invariant Natural Killer T cell function [PDF]
, 2023 Allison L. Balasko +4 more
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Development of invariant natural killer T cells [PDF]
Current Opinion in Immunology, 2016 Invariant natural killer T (iNKT) cells develop into functionally distinct subsets. Each subset expresses a unique combination of transcription factors that regulate cytokine gene transcription upon activation. The tissue distribution and localization within tissues also varies between subsets. Importantly, the relative abundance of the various subsets
openaire +2 more sources
Arthritis Care &Research, Accepted Article.Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation‐associated gene 5 antibody (MDA5 ab) associated dermatomyositis (DM). Methods Thirty patients with MDA5 ab DM were identified in a single center longitudinal cohort of 352 patients with ...
Jenice X Cheah +8 more
wiley +1 more source
Frontiers in Immunology, 2018 Natural killer cell receptors (NKRs) are germline-encoded transmembrane proteins that regulate the activation and homeostasis of NK cells as well as other lymphocytes.
Bruno Silva-Santos, Jessica Strid
doaj +1 more source
Journal of Experimental Medicine, 2003 Natural killer T (NKT) cells have been implicated in diverse immune responses ranging from suppression of autoimmunity to tumor rejection. Thymus-dependent NKT cells are positively selected by the major histocompatibility complex class I–like molecule ...
V. Sivakumar +4 more
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou +11 more
wiley +1 more source
Machine learning and experimental validation identified autophagy signature in hepatic fibrosis
Frontiers in ImmunologyBackgroundThe molecular mechanisms of hepatic fibrosis (HF), closely related to autophagy, remain unclear. This study aimed to investigate autophagy characteristics in HF.MethodsGene expression profiles (GSE6764, GSE49541 and GSE84044) were downloaded ...
Yushen Huang +5 more
doaj +1 more source
Intravital imaging – dynamic insights into Natural Killer T cell biology
Frontiers in Immunology, 2015 Natural killer T (NKT) cells were first recognized more than two decades ago as a separate and distinct lymphocyte lineage that modulates an expansive range of immune responses.
Pei Xiong Liew, Paul eKubes
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Comprehensive analysis of peripheral T-cell and natural killer/T-cell lymphoma in Asian patients: A multinational, multicenter, prospective registry study in Asia [PDF]
, 2021 Sang Eun Yoon +34 more
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