Results 21 to 30 of about 323,886 (359)
Natural Killer/T cell primary extranasal ileum lymphoma
Revista Peruana de Medicina Experimental y Salud Pública, 2020 Primary extranodal Natural Killer / T cell lymphoma (NKTL) on gastrointestinal tract is an uncommon and aggressive neoplasm. We present the case of a 51-year-old immunocompetent patient with a 2-month history of abdominal pain.
Rita López-Cabanillas +3 more
doaj +1 more source
Journal of Immunotherapy for Cancer, 2019 BackgroundNKT cells play an important role in anti-tumor immunity. Alpha-galactosylceramide (α-GalCer), a synthetic glycolipid is presented to natural killer T (NKT) cells by most antigen-presenting cells through CD1d molecules leading to activation of ...
S. Paul +3 more
semanticscholar +1 more source
Nasal Natural Killer/T Cell Lymphoma [PDF]
Indian Journal of Hematology and Blood Transfusion, 2014 Nasal natural killer/T cell lymphomas are locally destructive mid-facial necrotizing lesions. It is an uncommon disease but, usually shows a highly aggressive clinical course. Amongst the sino-nasal lymphomas, it is the most common type. The non-specific clinical features constitute a major stumbling block in the early diagnosis and management of these
Milind Anil, Bhatkule +3 more
openaire +2 more sources
Linking inflammation to natural killer T cell activation.
PLoS Biology, 2009 Immune activation is often associated with inflammation, but inflammation's role in the expansion of antigen-specific immune responses remains unclear. This primer focuses on recent findings that show how specific natural killer T cells are activated by ...
Mariolina Salio, Vincenzo Cerundolo
doaj +1 more source
Journal of Medical Case Reports, 2021 Introduction Extranodal, natural-killer/T-cell lymphoma of nasal type is a rare but aggressive disease usually presenting as progressive necrotic lesions in the nasal cavity that responds poorly to chemotherapy.
Fatemeh Adabifirouzjaei +3 more
doaj +1 more source
Natural Killer T Cell Activation Inhibits Hepatitis B Virus Replication in Vivo
Journal of Experimental Medicine, 2000 We have previously reported that hepatitis B virus (HBV)–specific CD8+ cytotoxic T lymphocytes and CD4+ helper T lymphocytes can inhibit HBV replication in the liver of HBV transgenic mice by secreting interferon (IFN)-γ when they recognize viral antigen.
K. Kakimi +3 more
semanticscholar +1 more source
Leukemia, 2018 Extranodal natural killer T-cell lymphoma (nasal type; NKTCL) is an aggressive malignancy strongly associated with Epstein-Barr virus (EBV) infection. However, the role of EBV in NKTCL development is unclear, largely due to the lack of information about ...
Roujun Peng +21 more
semanticscholar +1 more source
Adipose invariant natural killer T cells [PDF]
Immunology, 2014 SummaryAdipose tissue is a dynamic organ that makes up a substantial proportion of the body; in severe obesity it can account for 50% of body mass. Details of the unique immune system resident in human and murine adipose tissue are only recently emerging, and so it has remained a largely unexplored and unappreciated immune site until now.
openaire +2 more sources
Hepatic natural killer T‐cell and CD8+ T‐cell signatures in mice with nonalcoholic steatohepatitis
Hepatology Communications, 2017 Hepatic inflammation is a key pathologic feature of nonalcoholic steatohepatitis (NASH). Natural killer T (NKT) cells and clusters of differentiation (CD)8+ T‐cells are known to play an important role in obesity‐related adipose tissue inflammation.
Jashdeep Bhattacharjee +6 more
semanticscholar +1 more source
PLoS ONE, 2019 Glioblastoma is the leading malignant glioma with a poor prognosis. This study aimed to investigate the antitumor effects of natural killer cells in combination with temozolomide as the standard chemotherapeutic agent for glioblastoma.
Yoshitaka Tanaka +12 more
doaj +1 more source