Results 41 to 50 of about 323,886 (359)
Haematologica, 2009 Background An activated immune system has been observed in patients with myelodysplastic syndrome but its exact contribution to disease development and control is not fully clarified.
Martine E.D. Chamuleau +7 more
doaj +1 more source
Nature Communications, 2023 Numerous studies are exploring the use of cell adoptive therapies to treat hematological malignancies as well as solid tumors. However, there are numerous factors that dampen the immune response, including viruses like human immunodeficiency virus.
Jose M. Ayuso +17 more
doaj +1 more source
Recurrent GNAQ mutation encoding T96S in natural killer/T cell lymphoma
Nature Communications, 2019 Natural killer/T cell lymphoma (NKTCL) is a rare and aggressive malignancy with a higher prevalence in Asia and South America. However, the molecular genetic mechanisms underlying NKTCL remain unclear.
Zhaoming Li +30 more
semanticscholar +1 more source
Roles of Natural Killer T Cells and Natural Killer Cells in Kidney Injury [PDF]
International Journal of Molecular Sciences, 2019 Mouse natural killer T (NKT) cells and natural killer (NK) cells are innate immune cells that are highly abundant in the liver. In addition to their already-known antitumor and antimicrobial functions, their pathophysiological roles in the kidney have recently become evident.
Takahiro Uchida +5 more
openaire +2 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
JAMA Network Open, 2019 This cohort study assesses changes in survival probabilities and failure hazard after radiotherapy in adult patients with early-stage extranodal natural killer/T-cell lymphoma based on risk categories, previous survival, and treatment.
Xin Liu +22 more
semanticscholar +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
BMC Cancer, 2018 Background Salivary gland cancers are not sensitive to conventional radiotherapy or chemotherapy regimens. Therefore, the development of a new treatment strategy is of critical importance for improving the prognosis.
Yuji Makita +7 more
doaj +1 more source
Medicina, 2022 Background: The main etiology of acute pancreatitis includes biliary origin and alcohol, although various other causes include drugs (i.e., L-asparaginase) or malignant tumors.
Dong Wook Lee +2 more
doaj +1 more source
Natural killer and natural killer T cells in liver fibrosis
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2013 The liver lymphocyte population is enriched with natural killer (NK) cells, which play a key role in host defense against viral infection and tumor transformation. Recent evidence from animal models suggests that NK cells also play an important role in inhibiting liver fibrosis by selectively killing early or senescence activated hepatic stellate cells
Gao, Bin, Radaeva, Svetlana
openaire +2 more sources