Results 11 to 20 of about 50 (46)
, 2014 Natural killer (NK) cells are lymphocytes of the innate immune system. From a functional point of view, they have been well characterized for their ability to control tumors and infections. However, more recent data indicate that NK cells may also play an important immunoregulatory role.
Yenan T. Bryceson +3 more
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Natural killer cell deficiency [PDF]
Journal of Allergy and Clinical Immunology, 2013 Natural killer (NK) cells are part of the innate immune defense against infection and cancer and are especially useful in combating certain viral pathogens. The utility of NK cells in human health has been underscored by a growing number of persons who are deficient in NK cells and/or their functions. This can be in the context of a broader genetically
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Natural Killer Cells in the Lungs
Frontiers in Immunology, 2019 The lungs, a special site that is frequently challenged by tumors, pathogens and other environmental insults, are populated by large numbers of innate immune cells. Among these, natural killer (NK) cells are gaining increasing attention. Recent studies have revealed that NK cells are heterogeneous populations consisting of distinct subpopulations with ...
Jingjing Cong +4 more
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Natural Killer Cells in Psoriasis [PDF]
Journal of Innate Immunity, 2011 Psoriasis is one of the most common immune-mediated disorders. There is evidence that it is mediated by Th1 and, more recently, Th17 cells. The cytokine pattern, particularly the dominance of TNF-α, implicates the innate immune system in psoriasis pathogenesis. Of the many components of the innate immune system known to be involved in psoriatic lesions,
Brian Kirby +3 more
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Turning on Natural Killer Cells [PDF]
The Journal of Experimental Medicine, 2000 NK cells preferentially recognize and kill cells that lack expression of MHC class I ([1][1]). While inhibitory receptors expressing immunoreceptor tyrosine-based inhibition motifs prevent NK cells from harming tissues expressing normal levels of classical or nonclassical MHC class I (for a review,
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Biology of Natural Killer Cells
, 1989 Studies of cytotoxicity by human lymphocytes revealed not only that both allogeneic and syngeneic tumor cells were lysed in a non-MHC-restricted fashion, but also that lymphocytes from normal donors were often cytotoxic. Lymphocytes from any healthy donor, as well as peripheral blood and spleen lymphocytes from several experimental animals, in the ...
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Natural killer cells in meningiomas.
Histology and histopathology, 1991 A monoclonal antibody against the surface marker IOT-10 of natural killer (NK) cells was used to investigate the presence of these cells in a series of twenty intracranial meningiomas. In all of these tumours, IOT-10 positive NK cells were found in small numbers, mainly distributed among the tumor cells.
Vaquero, J. +4 more
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