Results 11 to 20 of about 17,952,172 (303)
Invariant natural killer T cells in lung diseases [PDF]
Experimental and Molecular Medicine, 2023 Invariant natural killer T (iNKT) cells are a subset of T cells that are characterized by a restricted T-cell receptor (TCR) repertoire and a unique ability to recognize glycolipid antigens.
Dongjin Jeong +2 more
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Unraveling Natural Killer T-Cells Development [PDF]
Frontiers in Immunology, 2018 Natural killer T-cells are a subset of innate-like T-cells with the ability to bridge innate and adaptive immunity. There is great interest in harnessing these cells to improve tumor therapy; however, greater understanding of invariant NKT (iNKT) cell ...
Sabrina Bianca Bennstein
doaj +3 more sources
Natural Killer T Cells in Cancer Immunotherapy [PDF]
Frontiers in Immunology, 2017 Natural killer T (NKT) cells are specialized CD1d-restricted T cells that recognize lipid antigens. Following stimulation, NKT cells lead to downstream activation of both innate and adaptive immune cells in the tumor microenvironment.
Shiny Nair, Madhav V. Dhodapkar
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Stimulation of Natural Killer T Cells by Glycolipids [PDF]
Molecules, 2013 Natural killer T (NKT) cells are a subset of T cells that recognize glycolipid antigens presented by the CD1d protein. The initial discovery of immunostimulatory glycolipids from a marine sponge and the T cells that respond to the compounds has led to ...
Brian L. Anderson +3 more
doaj +3 more sources
Characterisation of CD8neg and CD8+ human natural killer cell subsets [PDF]
, 2012 NK cells are CD3neg CD56+ lymphocytes that constitute about 10-15% of peripheral blood lymphocytes. They have an innate ability to recognise and kill virus infected cells and tumour cells.
Abdalla, Ibrahim.I.I.
core +6 more sources
Infections, Reactions of Natural Killer T Cells and Natural Killer Cells, and Kidney Injury [PDF]
International Journal of Molecular Sciences, 2022 Natural killer T (NKT) cells and NK cells are representative innate immune cells that perform antitumor and antimicrobial functions. The involvement of these cells in various renal diseases, including acute kidney injury (AKI), has recently become evident.
Uchida, Takahiro +2 more
openaire +2 more sources
Targeting natural killer cells and natural killer T cells in cancer [PDF]
Nature Reviews Immunology, 2012 Natural killer (NK) cells and natural killer T (NKT) cells are subsets of lymphocytes that share some phenotypical and functional similarities. Both cell types can rapidly respond to the presence of tumour cells and participate in antitumour immune responses. This has prompted interest in the development of innovative cancer therapies that are based on
Vivier, Eric +4 more
openaire +3 more sources
Natural killer cells and natural killer T cells in Lyme arthritis [PDF]
Arthritis Research & Therapy, 2013 Abstract Introduction Natural killer (NK) and natural killer T (NKT) cells provide a first line of defense against infection. However, these cells have not yet been examined in patients with Lyme arthritis, a late disease manifestation. Lyme arthritis usually resolves with antibiotic treatment.
Katchar, Kia +2 more
openaire +4 more sources
Targeting Natural Killer T Cells in Solid Malignancies
Cells, 2021 Natural killer T (NKT) cells are a unique subset of lymphocytes that recognize lipid antigens in the context of the non-classical class I MHC molecule, CD1d, and serve as a link between the innate and adaptive immune system through their expeditious ...
Zewde Ingram +6 more
doaj +1 more source