Results 11 to 20 of about 213,605 (262)
Invariant natural killer T cells in lung diseases [PDF]
Experimental and Molecular Medicine, 2023 Invariant natural killer T (iNKT) cells are a subset of T cells that are characterized by a restricted T-cell receptor (TCR) repertoire and a unique ability to recognize glycolipid antigens.
Dongjin Jeong +2 more
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Unraveling Natural Killer T-Cells Development [PDF]
Frontiers in Immunology, 2018 Natural killer T-cells are a subset of innate-like T-cells with the ability to bridge innate and adaptive immunity. There is great interest in harnessing these cells to improve tumor therapy; however, greater understanding of invariant NKT (iNKT) cell ...
Sabrina Bianca Bennstein
doaj +3 more sources
Stimulation of Natural Killer T Cells by Glycolipids [PDF]
Molecules, 2013 Natural killer T (NKT) cells are a subset of T cells that recognize glycolipid antigens presented by the CD1d protein. The initial discovery of immunostimulatory glycolipids from a marine sponge and the T cells that respond to the compounds has led to ...
Brian L. Anderson +3 more
doaj +3 more sources
Natural Killer T Cells in Cancer Immunotherapy [PDF]
Frontiers in Immunology, 2017 Natural killer T (NKT) cells are specialized CD1d-restricted T cells that recognize lipid antigens. Following stimulation, NKT cells lead to downstream activation of both innate and adaptive immune cells in the tumor microenvironment.
Shiny Nair, Madhav V. Dhodapkar
doaj +3 more sources
Infections, Reactions of Natural Killer T Cells and Natural Killer Cells, and Kidney Injury [PDF]
International Journal of Molecular Sciences, 2022 Natural killer T (NKT) cells and NK cells are representative innate immune cells that perform antitumor and antimicrobial functions. The involvement of these cells in various renal diseases, including acute kidney injury (AKI), has recently become evident.
Uchida, Takahiro +2 more
openaire +2 more sources
Natural killer cells and natural killer T cells in Lyme arthritis [PDF]
Arthritis Research & Therapy, 2013 Abstract Introduction Natural killer (NK) and natural killer T (NKT) cells provide a first line of defense against infection. However, these cells have not yet been examined in patients with Lyme arthritis, a late disease manifestation. Lyme arthritis usually resolves with antibiotic treatment.
Katchar, Kia +2 more
openaire +4 more sources
Targeting Natural Killer T Cells in Solid Malignancies
Cells, 2021 Natural killer T (NKT) cells are a unique subset of lymphocytes that recognize lipid antigens in the context of the non-classical class I MHC molecule, CD1d, and serve as a link between the innate and adaptive immune system through their expeditious ...
Zewde Ingram +6 more
doaj +1 more source
T cell regulation of natural killer cells [PDF]
Journal of Experimental Medicine, 2013 In light of their role in the immune response against tumors and viruses, natural killer (NK) cells represent a promising target for immunotherapy. Before this target is reached, the various mechanisms that control NK cell activity must first be identified and understood.
Kerdiles, Yann +2 more
openaire +2 more sources
Roles of Natural Killer T Cells and Natural Killer Cells in Kidney Injury [PDF]
International Journal of Molecular Sciences, 2019 Mouse natural killer T (NKT) cells and natural killer (NK) cells are innate immune cells that are highly abundant in the liver. In addition to their already-known antitumor and antimicrobial functions, their pathophysiological roles in the kidney have recently become evident.
Takahiro Uchida +5 more
openaire +2 more sources