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Pseudo Natural Products—Chemical Evolution of Natural Product Structure [PDF]

open access: yesAngewandte Chemie International Edition, 2021
Pseudo‐natural products (PNPs) combine natural product (NP) fragments in novel arrangements not accessible by current biosynthesis pathways. As such they can be regarded as non‐biogenic fusions of NP‐derived fragments.
George Karageorgis   +4 more
semanticscholar   +6 more sources

An infinite natural product [PDF]

open access: yesAnnales Mathematicae Silesianae, 32(1), 247-262 (2018), 2017
We study an infinite countable iteration of the natural product between ordinals. We present an "effective" way to compute this countable natural product, in the non trivial cases the result depends only on the natural sum of the degrees of the factors, where the degree of a nonzero ordinal is the largest exponent in its Cantor normal form ...
arxiv   +7 more sources

Chemical Evolution of Natural Product Structure

open access: yesJournal of the American Chemical Society, 2022
Natural products are the result of Nature’s exploration of biologically relevant chemical space through evolution and an invaluable source of bioactive small molecules for chemical biology and medicinal chemistry.
Michael Grigalunas   +2 more
semanticscholar   +1 more source

Natural Products [PDF]

open access: bronzeScience, 1973
Thomas E. Taylor
openalex   +2 more sources

Facile Detection of Light-Controlled Radical Scavengers from Natural Products Using In Situ UV-LED NMR Spectroscopy

open access: yesAntioxidants, 2022
With the recent development of chemical analysis technology, attention has been placed on natural light-sensitive compounds that exhibit photoreactivity to expand the structural diversity of natural product chemistry. Photochemical reactions that proceed
InWha Park   +6 more
doaj   +1 more source

Identification of Tyrosinase Inhibitors and Their Structure-Activity Relationships via Evolutionary Chemical Binding Similarity and Structure-Based Methods

open access: yesMolecules, 2021
Tyrosinase is an enzyme that plays a crucial role in the melanogenesis of humans and the browning of food products. Thus, tyrosinase inhibitors that are useful to the cosmetic and food industries are required.
Prasannavenkatesh Durai   +4 more
doaj   +1 more source

Desaturation of the Sphingofungin Polyketide Tail Results in Increased Serine Palmitoyltransferase Inhibition

open access: yesMicrobiology Spectrum, 2022
Serine palmitoyltransferase catalyzes the first step of the sphingolipid biosynthesis. Recently, sphingolipid homeostasis has been connected to several human diseases, making serine palmitoyltransferases an interesting therapeutic target.
Sandra Hoefgen   +6 more
doaj   +1 more source

From environmental adaptation to host survival: Attributes that mediate pathogenicity of Candida auris

open access: yesVirulence, 2022
Candida species are a major cause of invasive fungal infections. While Candida albicans, C. glabrata, C. parapsilosis, and C. tropicalis are the most dominant species causing life-threatening candidiasis, C.
Stefanie Allert   +8 more
doaj   +1 more source

Minerals Composition and Characterization of the Hatchery Eggshell Waste Treated with Different Preparation Methods

open access: yesJurnal Ilmu dan Teknologi Hasil Ternak, 2021
The preparation process needs to be carried out in the treatment of hatchery waste. The objective of the study was to determine the mineral content and characterization of the eggshell waste after preparation.
Ahmad Iskandar Setiyawan   +3 more
doaj   +1 more source

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