Results 121 to 130 of about 13,213,530 (364)
FEBS Open Bio, EarlyView.Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel +9 more
wiley +1 more source
Metagenomic natural product discovery in lichen provides evidence for a family of biosynthetic pathways in diverse symbioses [PDF]
, 2013 Annette Kampa +8 more
openalex +1 more source
FEBS Open Bio, EarlyView.CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
Isoproterenol Induced Myocardial Infarction: Protective Role of Natural Products [PDF]
, 2010 Aman Upaganlawar +2 more
openalex +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
Synthesis and Anti-Tuberculosis Activity of the Marine Natural Product Caulerpin and Its Analogues [PDF]
, 2014 Cristina Chay +4 more
openalex +1 more source
Recent Progress in Environmental Toxins-Induced Cardiotoxicity and Protective Potential of Natural Products [PDF]
, 2021 Yuanying Yang +3 more
openalex +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
FEBS Open Bio, EarlyView.HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Indonesian Journal of Chemistry, 2010 Preliminary studies on Terong Belanda (C. betacea ) have been carried out in this investigation with an aim to examine the presence of an alkaloid in the fruit of Terong Belanda.
Fredryk Mandey +2 more
doaj +1 more source
Modulation of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment by Natural Products [PDF]
, 2023 Jhon Jairo Calderon +4 more
openalex +1 more source