Results 11 to 20 of about 4,422,072 (371)
Antioxidants of Natural Products [PDF]
Antioxidants, 2021 Antioxidant ingredients are known to contribute to the beneficial effects of natural products in health promotion as well as disease prevention by reducing oxidative stress, caused by reactive oxygen or nitrogen species, in biological systems [...]
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Pseudo Natural Products—Chemical Evolution of Natural Product Structure [PDF]
Angewandte Chemie International Edition, 2021 AbstractPseudo‐natural products (PNPs) combine natural product (NP) fragments in novel arrangements not accessible by current biosynthesis pathways. As such they can be regarded as non‐biogenic fusions of NP‐derived fragments. They inherit key biological characteristics of the guiding natural product, such as chemical and physiological properties, yet ...
Luca Laraia +7 more
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BMC Bioinformatics, 2020 Background Despite continued efforts using chemical similarity methods in virtual screening, currently developed approaches suffer from time-consuming multistep procedures and low success rates.
Prasannavenkatesh Durai +3 more
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Iterative machine learning-based chemical similarity search to identify novel chemical inhibitors
Journal of Cheminformatics, 2023 Machine learning-based chemical screening has made substantial progress in recent years. However, these predictions often have low accuracy and high uncertainty when identifying new active chemical scaffolds.
Prasannavenkatesh Durai +4 more
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Antibiofilm and antibacterial activities of lupinifolin in combination with protein synthesis inhibitors against methicillin-resistant Staphylococcus aureus [PDF]
Journal of HerbMed Pharmacology, 2023 Introduction: Methicillin-resistant Staphylococcus aureus (MRSA)-derived biofilm formation is a crucial virulence factor, which essentially contributes to therapeutic challenges.
Parichart Kwaengmuang +4 more
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Natural Products for Medicine [PDF]
Journal of Biomedicine and Biotechnology, 2012 Throughout human history, natural products—including terrestrial plants, animal products, marine organisms, and products of microorganismal fermentation—have been used in traditional medicines. This historical experience with natural products as therapeutic agents has evolved to sophisticated isolation of active chemical entities from ...
Masa-Aki Shibata +3 more
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Bioactive Natural Products [PDF]
Journal of Chemistry, 2013 Bioactive natural products have never ceased to play an important role in the search of novel therapeutic agents. Natural products from the nature such as the plant and marine sources form an integral part of the living system, and they have existed ever since the beginning of life.Therefore, it is undeniable that works related to natural products ...
Ana Belen Martin-Diana +2 more
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mBio, 2020 Fumonisin (FB) mycotoxins produced by species of the genus Fusarium detrimentally affect human and animal health upon consumption, due to the inhibition of ceramide synthase.
Slavica Janevska +7 more
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Shipin gongye ke-ji, 2022 This study systematically determined the nutrient components, bioactive substances and heavy metal content of Stropharia rugosoannulata in Bo’ai County, and its nutritional value was analyzed and evaluated.
Bingnian JING +7 more
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Natural Diagonal Riemannian Almost Product and Para-Hermitian Cotangent Bundles [PDF]
, 2009 We obtain the natural diagonal almost product and locally product structures on the total space of the cotangent bundle of a Riemannian manifold. We find the Riemannian almost product (locally product) and the (almost) para-Hermitian cotangent bundles of
A. Al-Aqeel +64 more
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