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Click Chemistry in Natural Product Modification [PDF]
Click chemistry is perhaps the most powerful synthetic toolbox that can efficiently access the molecular diversity and unique functions of complex natural products up to now.
Xiang Zhang+5 more
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Recent advances in the chemistry of natural products [PDF]
Abstract
R. B. Woodward
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Antibiofilm and antibacterial activities of lupinifolin in combination with protein synthesis inhibitors against methicillin-resistant Staphylococcus aureus [PDF]
Introduction: Methicillin-resistant Staphylococcus aureus (MRSA)-derived biofilm formation is a crucial virulence factor, which essentially contributes to therapeutic challenges.
Parichart Kwaengmuang+4 more
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The chemistry of isoindole natural products [PDF]
This review highlights the chemical and biological aspects of natural products containing an oxidized or reduced isoindole skeleton. This motif is found in its intact or modified form in indolocarbazoles, macrocyclic polyketides (cytochalasan alkaloids), the aporhoeadane alkaloids, meroterpenoids from Stachybotrys species and anthraquinone-type ...
Thomas Magauer, Klaus Speck
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The crystal structure of 13-(pyrazole-1-yl-4-carbonitrile)-matrine, C19H25N5O
C19H25N5O, monoclinic, P21 (no. 4), a = 16.0600(2) Å, b = 5.3992(1) Å, c = 19.8514(2) Å, β = 94.260(1)°, V = 1716.58(4) Å3, Z = 4, Rgt (F) = 0.0350, wRref(F2) = 0.0908, T = 100.00(10) K.
Li Jun-Jie+8 more
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Preliminary studies on Terong Belanda (C. betacea ) have been carried out in this investigation with an aim to examine the presence of an alkaloid in the fruit of Terong Belanda.
Fredryk Mandey+2 more
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Nitroimidazole represents one of the most essential and unique scaffolds in drug discovery since its discovery in the 1950s. It was K. Maeda in Japan who reported in 1953 the first nitroimidazole as a natural product from Nocardia mesenterica with ...
Ria Gupta+5 more
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Isolation and characterization of starch from Limnophila aromatica
Starch is one of the digestible natural polymers found in vascular plants. This natural polymer is the primary source of polysaccharides to produce energy for humans.
Cynthia Wijaya+7 more
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The G-quadruplex formed in KRAS oncogene promoter (KRAS-G4) is a transcriptional modulator and amenable to small molecule targeting. Herein, the authors report the NMR solution structures of a bulge-containing KRAS-G4 that bound to two small molecules ...
Kai-Bo Wang+10 more
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