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Click Chemistry in Natural Product Modification [PDF]
Frontiers in Chemistry, 2021 Click chemistry is perhaps the most powerful synthetic toolbox that can efficiently access the molecular diversity and unique functions of complex natural products up to now.
Xiang Zhang +5 more
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The chemistry of isoindole natural products [PDF]
Beilstein Journal of Organic Chemistry, 2013 This review highlights the chemical and biological aspects of natural products containing an oxidized or reduced isoindole skeleton. This motif is found in its intact or modified form in indolocarbazoles, macrocyclic polyketides (cytochalasan alkaloids), the aporhoeadane alkaloids, meroterpenoids from Stachybotrys species and anthraquinone-type ...
Klaus Speck, Thomas Magauer
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Natural Product Chemistry and Biological Research [PDF]
International Journal of Molecular SciencesNatural products are substances found in nature that have not been significantly modified by humans [...]
Francisco Les +2 more
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Antibiofilm and antibacterial activities of lupinifolin in combination with protein synthesis inhibitors against methicillin-resistant Staphylococcus aureus [PDF]
Journal of HerbMed Pharmacology, 2023 Introduction: Methicillin-resistant Staphylococcus aureus (MRSA)-derived biofilm formation is a crucial virulence factor, which essentially contributes to therapeutic challenges.
Parichart Kwaengmuang +4 more
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Natural product chemistry for drug discovery [PDF]
The Journal of Antibiotics, 2011 S. Hashimoto
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Chemical Evolution of Natural Product Structure
Journal of the American Chemical Society, 2022 Natural products are the result of Nature’s exploration of biologically relevant chemical space through evolution and an invaluable source of bioactive small molecules for chemical biology and medicinal chemistry.
Michael Grigalunas +2 more
semanticscholar +1 more source
Natural product reports (Print), 2020 Covering: up to the end of 2020.The machine learning field can be defined as the study and application of algorithms that perform classification and prediction tasks through pattern recognition instead of explicitly defined rules.
David Prihoda +7 more
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The crystal structure of 13-(pyrazole-1-yl-4-carbonitrile)-matrine, C19H25N5O
Zeitschrift für Kristallographie - New Crystal Structures, 2021 C19H25N5O, monoclinic, P21 (no. 4), a = 16.0600(2) Å, b = 5.3992(1) Å, c = 19.8514(2) Å, β = 94.260(1)°, V = 1716.58(4) Å3, Z = 4, Rgt (F) = 0.0350, wRref(F2) = 0.0908, T = 100.00(10) K.
Li Jun-Jie +8 more
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Integrated Metabolomic–Genomic Workflows Accelerate Microbial Natural Product Discovery
Analytical Chemistry, 2022 The pairing of analytical chemistry with genomic techniques represents a new wave in natural product chemistry. With an increase in the availability of sequencing and assembly of microbial genomes, interrogation into the biosynthetic capability of ...
Nicole E. Avalon, A. Murray, B. Baker
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