Results 1 to 10 of about 1,472,655 (353)
Click Chemistry in Natural Product Modification
Click chemistry is perhaps the most powerful synthetic toolbox that can efficiently access the molecular diversity and unique functions of complex natural products up to now.
Xiang Zhang +5 more
doaj +2 more sources
Bioinspired total syntheses of natural products: a personal adventure [PDF]
Bioinspired total synthesis represents an important concept to guide the designing of powerful synthetic strategies. Our group has a long-time interest and experience in designing synthetic strategies through analyzing the biosynthetic pathway of natural
Zhengyi Qin +7 more
doaj +2 more sources
Natural Product Chemistry and Biological Research. [PDF]
Les F, Valero MS, Arruebo MP.
europepmc +3 more sources
Natural product chemistry of gorgonian corals of genus Junceella--part II. [PDF]
Wu YC +12 more
europepmc +3 more sources
Antibiofilm and antibacterial activities of lupinifolin in combination with protein synthesis inhibitors against methicillin-resistant Staphylococcus aureus [PDF]
Introduction: Methicillin-resistant Staphylococcus aureus (MRSA)-derived biofilm formation is a crucial virulence factor, which essentially contributes to therapeutic challenges.
Parichart Kwaengmuang +4 more
doaj +1 more source
The crystal structure of 13-(pyrazole-1-yl-4-carbonitrile)-matrine, C19H25N5O
C19H25N5O, monoclinic, P21 (no. 4), a = 16.0600(2) Å, b = 5.3992(1) Å, c = 19.8514(2) Å, β = 94.260(1)°, V = 1716.58(4) Å3, Z = 4, Rgt (F) = 0.0350, wRref(F2) = 0.0908, T = 100.00(10) K.
Li Jun-Jie +8 more
doaj +1 more source
Preliminary studies on Terong Belanda (C. betacea ) have been carried out in this investigation with an aim to examine the presence of an alkaloid in the fruit of Terong Belanda.
Fredryk Mandey +2 more
doaj +1 more source
Click-based synthesis and proteomic profiling of lipstatin analogues [PDF]
Using click chemistry to enable both structural diversity and proteome profiling within a natural product derived library, two out of nineteen lipstatin analogues showed similar activity to Orlistat against fatty acid synthase (FAS), but with an improved
Adam +38 more
core +1 more source
Perylenequinones from an endophytic Alternaria sp. of Pinus ponderosa
The differential solvent extraction and further purification of fractions of endophytic Alternaria sp. isolated from Pinus ponderosa led to the isolation of further two perylenequinone compounds as 3,6,6a,9,10-pentahydroxy-7,8-epoxy-4-oxo-4,5,6,6a,6b,7,8,
Mudasir A. Tantry +7 more
doaj +1 more source
Identification of a new p53/MDM2 inhibitor motif inspired by studies of chlorofusin [PDF]
Previous studies on the natural product chlorofusin have shown that the full peptide and azaphilone structure are required for inhibition of the interaction between MDM2 and p53.
Clark +24 more
core +1 more source

