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Click Chemistry in Natural Product Modification [PDF]

open access: yesFrontiers in Chemistry, 2021
Click chemistry is perhaps the most powerful synthetic toolbox that can efficiently access the molecular diversity and unique functions of complex natural products up to now.
Xiang Zhang   +5 more
doaj   +6 more sources

Collected mass spectrometry data on monoterpene indole alkaloids from natural product chemistry research [PDF]

open access: yesSci Data, 2019
This Data Descriptor announces the submission to public repositories of the monoterpene indole alkaloid database (MIADB), a cumulative collection of 172 tandem mass spectrometry (MS/MS) spectra from multiple research projects conducted in eight natural ...
Alexander E. Fox Ramos   +28 more
semanticscholar   +2 more sources

Enantiomeric Mixtures in Natural Product Chemistry: Separation and Absolute Configuration Assignment [PDF]

open access: yesMolecules, 2018
Chiral natural product molecules are generally assumed to be biosynthesized in an enantiomerically pure or enriched fashion. Nevertheless, a significant amount of racemates or enantiomerically enriched mixtures has been reported from natural sources ...
Andrea N L Batista   +3 more
semanticscholar   +2 more sources

Bioautography and its scope in the field of natural product chemistry [PDF]

open access: yesJ Pharm Anal, 2014
Medicinal plants, vegetables and fruits are the sources of huge number of bioactive lead/scaffolds with therapeutic and nutraceutical importance. Bioautography is a means of target-directed isolation of active molecules on chromatogram.
S. Dewanjee   +4 more
semanticscholar   +2 more sources

Natural product anticipation through synthesis

open access: yesNature Reviews Chemistry, 2022
Natural product synthesis remains one of the most vibrant and intellectually rewarding areas of chemistry, although the justifications for pursuing it have evolved over time.
Belinda E Hetzler   +2 more
exaly   +2 more sources

Natural Product Chemistry and Biological Research. [PDF]

open access: yesInt J Mol Sci
Natural products are substances found in nature that have not been significantly modified by humans [...]
Les F, Valero MS, Arruebo MP.
europepmc   +3 more sources

Antibiofilm and antibacterial activities of lupinifolin in combination with protein synthesis inhibitors against methicillin-resistant Staphylococcus aureus [PDF]

open access: yesJournal of HerbMed Pharmacology, 2023
Introduction: Methicillin-resistant Staphylococcus aureus (MRSA)-derived biofilm formation is a crucial virulence factor, which essentially contributes to therapeutic challenges.
Parichart Kwaengmuang   +4 more
doaj   +1 more source

The chemistry of isoindole natural products [PDF]

open access: yesBeilstein Journal of Organic Chemistry, 2013
This review highlights the chemical and biological aspects of natural products containing an oxidized or reduced isoindole skeleton. This motif is found in its intact or modified form in indolocarbazoles, macrocyclic polyketides (cytochalasan alkaloids), the aporhoeadane alkaloids, meroterpenoids from Stachybotrys species and anthraquinone-type ...
Klaus Speck, Thomas Magauer
openaire   +3 more sources

Chemical Evolution of Natural Product Structure

open access: yesJournal of the American Chemical Society, 2022
Natural products are the result of Nature’s exploration of biologically relevant chemical space through evolution and an invaluable source of bioactive small molecules for chemical biology and medicinal chemistry.
Michael Grigalunas   +2 more
semanticscholar   +1 more source

The application potential of machine learning and genomics for understanding natural product diversity, chemistry, and therapeutic translatability.

open access: yesNatural product reports (Print), 2020
Covering: up to the end of 2020.The machine learning field can be defined as the study and application of algorithms that perform classification and prediction tasks through pattern recognition instead of explicitly defined rules.
David Prihoda   +7 more
semanticscholar   +1 more source

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