Antibiofilm and antibacterial activities of lupinifolin in combination with protein synthesis inhibitors against methicillin-resistant Staphylococcus aureus [PDF]
Journal of HerbMed Pharmacology, 2023 Introduction: Methicillin-resistant Staphylococcus aureus (MRSA)-derived biofilm formation is a crucial virulence factor, which essentially contributes to therapeutic challenges.
Parichart Kwaengmuang +4 more
doaj +1 more source
Click Chemistry in Natural Product Modification
Frontiers in Chemistry, 2021 Click chemistry is perhaps the most powerful synthetic toolbox that can efficiently access the molecular diversity and unique functions of complex natural products up to now.
Xiang Zhang +5 more
doaj +1 more source
The crystal structure of 13-(pyrazole-1-yl-4-carbonitrile)-matrine, C19H25N5O
Zeitschrift für Kristallographie - New Crystal Structures, 2021 C19H25N5O, monoclinic, P21 (no. 4), a = 16.0600(2) Å, b = 5.3992(1) Å, c = 19.8514(2) Å, β = 94.260(1)°, V = 1716.58(4) Å3, Z = 4, Rgt (F) = 0.0350, wRref(F2) = 0.0908, T = 100.00(10) K.
Li Jun-Jie +8 more
doaj +1 more source
Indonesian Journal of Chemistry, 2010 Preliminary studies on Terong Belanda (C. betacea ) have been carried out in this investigation with an aim to examine the presence of an alkaloid in the fruit of Terong Belanda.
Fredryk Mandey +2 more
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Facilitating biomimetic syntheses of borrerine derived alkaloids by means of flow-chemical methods [PDF]
, 2015 Flow chemistry is widely used nowadays in synthetic chemistry and has increasingly been applied to complex natural product synthesis. However, to date flow chemistry has not found a place in the area of biomimetic synthesis.
Kamptmann, SB, Ley, SV
core +1 more source
Click-based synthesis and proteomic profiling of lipstatin analogues [PDF]
, 2010 Using click chemistry to enable both structural diversity and proteome profiling within a natural product derived library, two out of nineteen lipstatin analogues showed similar activity to Orlistat against fatty acid synthase (FAS), but with an improved
Adam +38 more
core +1 more source
Perylenequinones from an endophytic Alternaria sp. of Pinus ponderosa
Heliyon, 2018 The differential solvent extraction and further purification of fractions of endophytic Alternaria sp. isolated from Pinus ponderosa led to the isolation of further two perylenequinone compounds as 3,6,6a,9,10-pentahydroxy-7,8-epoxy-4-oxo-4,5,6,6a,6b,7,8,
Mudasir A. Tantry +7 more
doaj +1 more source
Isolation and characterization of starch from Limnophila aromatica
Heliyon, 2019 Starch is one of the digestible natural polymers found in vascular plants. This natural polymer is the primary source of polysaccharides to produce energy for humans.
Cynthia Wijaya +7 more
doaj +1 more source
Furan-site transformations of obacunone as potent insecticidal agents
Heliyon, 2018 Furan ring is a key pharmacophore for insecticidal activity of limoninoids. To develop natural-product-based insecticidal agents, a series of furan-site transformations (2, 3 and 3a–j) of obacunone were synthesized by selective bromination and following ...
Ping Xiang +5 more
doaj +1 more source
Sonogashira diversification of unprotected halotryptophans, halotryptophan containing tripeptides; and generation of a new to nature bromo-natural product and its diversification in water [PDF]
, 2017 The blending together of synthetic chemistry with natural product biosynthesis represents a potentially powerful approach to synthesis; to enable this, further synthetic tools and methodologies are needed.
Abou Fayad, A +8 more
core +2 more sources