Results 1 to 10 of about 1,020,429 (254)

Click Chemistry in Natural Product Modification [PDF]

open access: yesFrontiers in Chemistry, 2021
Click chemistry is perhaps the most powerful synthetic toolbox that can efficiently access the molecular diversity and unique functions of complex natural products up to now.
Xiang Zhang   +5 more
doaj   +3 more sources

Natural Product Chemistry and Biological Research. [PDF]

open access: yesInt J Mol Sci
Natural products are substances found in nature that have not been significantly modified by humans [...]
Les F, Valero MS, Arruebo MP.
europepmc   +3 more sources

Antibiofilm and antibacterial activities of lupinifolin in combination with protein synthesis inhibitors against methicillin-resistant Staphylococcus aureus [PDF]

open access: yesJournal of HerbMed Pharmacology, 2023
Introduction: Methicillin-resistant Staphylococcus aureus (MRSA)-derived biofilm formation is a crucial virulence factor, which essentially contributes to therapeutic challenges.
Parichart Kwaengmuang   +4 more
doaj   +1 more source

The chemistry of isoindole natural products [PDF]

open access: yesBeilstein Journal of Organic Chemistry, 2013
This review highlights the chemical and biological aspects of natural products containing an oxidized or reduced isoindole skeleton. This motif is found in its intact or modified form in indolocarbazoles, macrocyclic polyketides (cytochalasan alkaloids), the aporhoeadane alkaloids, meroterpenoids from Stachybotrys species and anthraquinone-type ...
Thomas Magauer, Klaus Speck
openaire   +5 more sources

The crystal structure of 13-(pyrazole-1-yl-4-carbonitrile)-matrine, C19H25N5O

open access: yesZeitschrift für Kristallographie - New Crystal Structures, 2021
C19H25N5O, monoclinic, P21 (no. 4), a = 16.0600(2) Å, b = 5.3992(1) Å, c = 19.8514(2) Å, β = 94.260(1)°, V = 1716.58(4) Å3, Z = 4, Rgt (F) = 0.0350, wRref(F2) = 0.0908, T = 100.00(10) K.
Li Jun-Jie   +8 more
doaj   +1 more source

A PRELIMINARY QUALITATIVE STUDY OF AN ALKALOID IN THE FRUIT OF TERONG BELANDA (Cyphomandra betacea, Cav)

open access: yesIndonesian Journal of Chemistry, 2010
Preliminary studies on Terong Belanda (C. betacea ) have been carried out in this investigation with an aim to examine the presence of an alkaloid in the fruit of Terong Belanda.
Fredryk Mandey   +2 more
doaj   +1 more source

Functionalized Nitroimidazole Scaffold Construction and Their Pharmaceutical Applications: A 1950–2021 Comprehensive Overview

open access: yesPharmaceuticals, 2022
Nitroimidazole represents one of the most essential and unique scaffolds in drug discovery since its discovery in the 1950s. It was K. Maeda in Japan who reported in 1953 the first nitroimidazole as a natural product from Nocardia mesenterica with ...
Ria Gupta   +5 more
doaj   +1 more source

Lemon Juice as a Natural Catalyse for Synthesis of Shiff’s base: A Green Chemistry Approach [PDF]

open access: yes, 2018
The advantages of the use of natural catalysts are eco-friendly, inexpensive, high yields, nonhazardous and short reaction times. The utilization of green chemistry techniques is the elimination of solvents during chemical processes or the replacement of
Alikhani, A. (Azadeh)   +2 more
core   +1 more source

Perylenequinones from an endophytic Alternaria sp. of Pinus ponderosa

open access: yesHeliyon, 2018
The differential solvent extraction and further purification of fractions of endophytic Alternaria sp. isolated from Pinus ponderosa led to the isolation of further two perylenequinone compounds as 3,6,6a,9,10-pentahydroxy-7,8-epoxy-4-oxo-4,5,6,6a,6b,7,8,
Mudasir A. Tantry   +7 more
doaj   +1 more source

Click-based synthesis and proteomic profiling of lipstatin analogues [PDF]

open access: yes, 2010
Using click chemistry to enable both structural diversity and proteome profiling within a natural product derived library, two out of nineteen lipstatin analogues showed similar activity to Orlistat against fatty acid synthase (FAS), but with an improved
Adam   +38 more
core   +1 more source

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