Results 31 to 40 of about 1,020,429 (254)

Sonogashira diversification of unprotected halotryptophans, halotryptophan containing tripeptides; and generation of a new to nature bromo-natural product and its diversification in water [PDF]

, 2017
The blending together of synthetic chemistry with natural product biosynthesis represents a potentially powerful approach to synthesis; to enable this, further synthetic tools and methodologies are needed.
Abou Fayad, A, Bown, R T, Cartmell, C, Corr, M J, Goss, R J M, Poirot, P, Pubill-Ulldemolins, C, Sharma, S V, Smith, D R M   +8 more
core   +2 more sources

The crystal structure of a matrine derivative: 41S,7aS,12S,13aR,13bR)-12-(4-methylpiperazin-1-yl)dodecahydro-1H,5H,10H-dipyrido[2,1-f:3′,2′,1′-ij][1,6]naphthyridin-10-one, C20H34N4O

Zeitschrift für Kristallographie - New Crystal Structures, 2018
C20H34N4O, triclinic, P1 (no. 1), a = 7.8545(6) Å, b = 10.8802(9) Å, c = 12.3714(9) Å, α = 73.200(7)°, β = 75.372(6)°, γ = 71.091(7)°, V = 942.65(13) Å3, Z = 2, Rgt(F) = 0.0591, wRref(F2) = 0.1641, T = 293(2) K.
Cheng Xing-An, Zhan-Mei Liu, Bo Wu, Su-Qing Huang, Xia-Ling Xiong, Xu-Hong Jiang   +5 more
doaj   +1 more source

Xanthine scaffold: scope and potential in drug development

Heliyon, 2018
Medicinal plants have been the basis for discovery of various important marketed drugs. Xanthine is one such lead molecule. Xanthines in various forms (caffeine, theophylline, theobromine, etc) are abode in tea, coffee, cocoa, chocolate etc.
Nivedita Singh, Ashwinee Kumar Shreshtha, M.S. Thakur, Sanjukta Patra   +3 more
doaj   +1 more source

Infinite-body optimal transport with Coulomb Cost [PDF]

, 2013
We introduce and analyze symmetric infinite-body optimal transport (OT) problems with cost function of pair potential form. We show that for a natural class of such costs, the optimizer is given by the independent product measure all of whose factors are
Cotar, Codina, Friesecke, Gero, Pass, Brendan   +2 more
core   +3 more sources

Phenolic profiling and therapeutic potential of local flora of Azad Kashmir; In vitro enzyme inhibition and antioxidant

Open Chemistry, 2017
The current study supports the phytochemical screening, evaluation of antioxidant and enzyme inhibition potential and correlations between antioxidant activities and phenolics of Rumex dentatus (Family: Polygonaceae), Mentha spicata (Family: Lamiaceae ...
Raza Muhammad Asam, Danish Muhammad, Mushtaq Mahvish, Sumrra Sajjad Hussain, Saqib Zenab, Rehman Shafiq Ur   +5 more
doaj   +1 more source

Antibiofilm formation activity of lupinifolin isolated from Derris reticulata stems against Enterococcus faecalis [PDF]

Journal of HerbMed Pharmacology
Introduction: The biofilm formation capability of Enterococcus faecalis is one of the key virulence factors contributing to its multidrug resistance and therapeutic challenges.
Pawitra Pulbutr, Kridsanun Seelakot, Nicharee Kumphupong, Sakulrat Rattanakiat   +3 more
doaj   +1 more source

Canvass: a crowd-sourced, natural-product screening library for exploring biological space [PDF]

, 2018
NCATS thanks Dingyin Tao for assistance with compound characterization. This research was supported by the Intramural Research Program of the National Center for Advancing Translational Sciences, National Institutes of Health (NIH). R.B.A.
Andrade, Rodrigo B., Bougie, Danielle, Boxer, Matthew B., Brimacombe, Kyle R., Brown, Lauren E., Brown, M Kevin, Burns, Noah Z., Cha, Jin K., Cheff, Dorian M., Cheng, Ken, Clardy, Jon, Clement, Jason A., Coussens, Nathan P., Crooks, Peter A., Cuny, Gregory D., Dillon, Christopher, Dorjsuren, Dorjbal, Eastman, Richard T., Ganor, Jake, Garg, Neil K., Goess, Brian C., Grossman, Robert B., Guha, Rajarshi, Hall, Matthew D., Henderson, Mark J., Huang, Ruili, Hughes, Chambers C., Iannotti, Michael J., Inglese, James, Itkin, Zina, Jadhav, Ajit, Johnston, Jeffrey N., Joullie, Madeleine M., Karavadhi, Surendra, Kearney, Sara E., Kinghorn, A. Douglas, Kingston, David G. I., Klumpp-Thomas, Carleen, Krische, Michael J., Kwon, Ohyun, Lee, Tobie D., Lynch, Caitlin, Maimone, Thomas J., Majumdar, Susruta, Maloney, Katherine N., Mevers, Emily E., Michael, Sam, Mohamed, Enas, Moreno, Jesus, Morrill, Lucas A., Murphy, Brian T., Nagorny, Pavel, Olson, David E., Overman, Larry E., Picazo, Elias, Porco, John A., Ren, Tianjing, Rivas, Fatima, Rohde, Jason M., Ross, Samir A., Roth, Jacob S., Sakamuru, Srilatha, Sarpong, Richmond, Sharma, Indrajeet, Shaw, Jared T., Shen, Ben, Shen, Min, Shi, Wei, Shinn, Paul, Simeonov, Anton, Snyder, John K., Stephenson, Corey R. J., Sun, Wei, Susick, Robert B., Tan, Derek S., Tang, Yi, Taylor, Richard E., Thomson, Regan J., Titus, Steven A., Verano, Alyssa L., Vosburg, David A., Wan, Kanny K., Wu, Jimmy, Wuest, William M., Xia, Menghang, Xu, Zhengren, Yasgar, Adam, Zahoranszky-Kohalmi, Gergely, Zakarian, Armen, Zhang, Ya-Qin, Zhang, Yufeng, Zhao, Jinghua, Zhao, Tongan, Zheng, Wei, Zuo, Zhong   +94 more
core   +1 more source

Optimization of choline chloride-glycerol based natural deep eutectic solvent for extraction bioactive substances from Cinnamomum burmannii barks and Caesalpinia sappan heartwoods

Heliyon, 2019
Indonesian cassia (Cinnamomum burmannii Blume) is commonly used as a condiment. It reportedly contains a number of major phytochemical constituents such as trans-cinnamaldehyde and coumarin. Sappan wood (Caesalpinia sappan) is a native plant of Southeast
Aditya Sindu Sakti, Fadlina Chany Saputri, Abdul Mun'im   +2 more
doaj   +1 more source

Photochemical Approaches to Complex Chemotypes: Applications in Natural Product Synthesis. [PDF]

, 2016
The use of photochemical transformations is a powerful strategy that allows for the formation of a high degree of molecular complexity from relatively simple building blocks in a single step. A central feature of all light-promoted transformations is the
Kärkäs, Markus D., Porco, John A., Stephenson, Corey R.J.   +2 more
core   +5 more sources

Non-natural Olefin Cyclopropanation Catalyzed by Diverse Cytochrome P450s and Other Hemoproteins [PDF]

, 2014
Recent work has shown that engineered variants of cytochrome P450_(BM3) (CYP102A1) efficiently catalyze non-natural reactions, including carbene and nitrene transfer reactions.
Arnold, Frances H., Dodani, Sheel C., Heel, Thomas, McIntosh, John A., Meyerowitz, Joseph T.   +4 more
core   +1 more source