Results 1 to 10 of about 12,894,068 (258)

Natural products in drug discovery: advances and opportunities

Nature Reviews Drug Discovery, 2021
Natural products and their structural analogues have historically made a major contribution to pharmacotherapy, especially for cancer and infectious diseases.
Atanas G Atanasov, Sergey B Zotchev, Verena M Dirsch   +2 more
exaly   +2 more sources

Metabolomics in the Context of Plant Natural Products Research: From Sample Preparation to Metabolite Analysis [PDF]

Metabolites, 2020
Plant-derived natural products have long been considered a valuable source of lead compounds for drug development. Natural extracts are usually composed of hundreds to thousands of metabolites, whereby the bioactivity of natural extracts can be ...
Mohamed A. Salem, Leonardo Perez de Souza, Ahmed Serag, Alisdair R. Fernie, Mohamed A. Farag, Shahira M. Ezzat, Saleh Alseekh   +6 more
openalex   +2 more sources

Evaluation of Nutritional Ingredients, Biologically Active Materials, and Pharmacological Activities of Stropharia rugosoannulata Grown under the Bamboo Forest and in the Greenhouse

Journal of Food Quality, 2021
Evaluations of the nutritional ingredients, biologically active materials, and pharmacological activities (antibacterial and antioxidant) of two types of Stropharia rugosoannulata, grown under the bamboo forest and in the greenhouse, respectively, were ...
Lei Wei, Bingnian Jing, Xiao Li, Yueying Hou, Xiaoyang Xie, Zhiyao Wang, Yuqing Liu, Yong Zhou, Xia Chang, Wei Wang   +9 more
doaj   +1 more source

Chemical Composition, Antibacterial Test, and Antioxidant Activity of Essential Oils from Fresh and Dried Stropharia rugosoannulata

Journal of Chemistry, 2023
The essential oils, respectively, from fresh and dried Stropharia rugosoannulata fruiting bodies, an important edible mushroom, have been studied for their chemical composition, antibacterial capacity, and antioxidant activity.
Lei Wei, Wei Wang, Yueying Hou, Xiaoyang Xie, Xiao Li, Fei Chen, Zhiyao Wang, Yong Zhou, Feifei Li, Bingnian Jing   +9 more
doaj   +1 more source

Phytochemical Investigation of Egyptian Riverhemp: A Potential Source of Antileukemic Metabolites

Journal of Chemistry, 2022
As part of our research group’s continuous efforts to find alternative treatments for cancer, the aqueous ethanol extract of Sesbania sesban L. Merr. (SS, Egyptian riverhemp) demonstrated an antileukemic activity against K562 cell line.
Shimaa M. Abdelgawad, Mona H. Hetta, Mohamed A. Ibrahim, Premalatha Balachandran, Jin Zhang, Mei Wang, Wagdy M. Eldehna, Ghada A. Fawzy, Hesham I. El-Askary, Samir A. Ross   +9 more
doaj   +1 more source

Natural Products as Anticancer Agents: Current Status and Future Perspectives

Molecules, 2022
Natural products have been an invaluable and useful source of anticancer agents over the years. Several compounds have been synthesized from natural products by modifying their structures or by using naturally occurring compounds as building blocks in ...
Abid Naeem, Peng-yi Hu, Ming Yang, Jing Zhang, Yali Liu, Weifeng Zhu, Qin Zheng   +6 more
semanticscholar   +1 more source

Design of 3D Hybrid Plant Extract/Marine and Bovine Collagen Matrixes as Potential Dermal Scaffolds for Skin Wound Healing

The Scientific World Journal, 2022
Tissue engineering involves the use of smart biomimetic hybrid matrices to reinforce the cellular interaction with the matrix and restore native properties after regeneration.
Aida Lahmar, Maroua Rjab, Fairouz Sioud, Mouna Selmi, Abir Salek, Soumaya Kilani-Jaziri, Leila Chekir Ghedira   +6 more
doaj   +1 more source

Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019.

Journal of Natural Products, 2020
This review is an updated and expanded version of the five prior reviews that were published in this journal in 1997, 2003, 2007, 2012, and 2016. For all approved therapeutic agents, the time frame has been extended to cover the almost 39 years from the ...
D. Newman, G. Cragg
semanticscholar   +1 more source

Plant-derived natural products for drug discovery: current approaches and prospects

The Nucleus, 2022
Nature has abundant source of drugs that need to be identified/purified for use as essential biologics, either individually or in combination in the modern medical field.
Noohi Nasim, I. S. Sandeep, Sujata Mohanty   +2 more
semanticscholar   +1 more source

Non-Alcoholic Fatty Liver Disease (NAFLD) Pathogenesis and Natural Products for Prevention and Treatment

International Journal of Molecular Sciences, 2022
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease, affecting approximately one-quarter of the global population, and has become a world public health issue.
Xiangyu Guo, Xunzhe Yin, Zuojia Liu, Jin Wang   +3 more
semanticscholar   +1 more source