Results 91 to 100 of about 4,373,264 (365)

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Practical challenges in data‐driven interpolation: Dealing with noise, enforcing stability, and computing realizations

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView., 2023
Summary In this contribution, we propose a detailed study of interpolation‐based data‐driven methods that are of relevance in the model reduction and also in the systems and control communities. The data are given by samples of the transfer function of the underlying (unknown) model, that is, we analyze frequency‐response data.
Quirin Aumann, Ion Victor Gosea
wiley   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Plausible influence of atorvastatin and dietary legumes (horsegram and groundnut) in dyslipidemia in experimental rodents

open access: yesPhytomedicine Plus, 2021
Background: Dyslipidemia a common pathology in metabolic syndrome results due to various factors. Although statins are proven for its beneficial role in the management of hyperlipidemia, plant-based foods and their ingredients are still a cornerstone of ...
Malarvizhi R   +5 more
doaj  

On the tensor product construction for q-differential algebras [PDF]

open access: yesarXiv, 1997
We show that for $q\not=-1$ the q-graded tensor product fails to preserve the q-differential structure of the product algebra and therefore there is no natural tensor product construction for q-differential algebras.
arxiv  

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

Effect of tobacco–radish rotation for different years on bacterial wilt and rhizosphere microbial communities

open access: yesAMB Express
Tobacco bacterial wilt is a major limiting factor for tobacco production and development, and it is more likely to occur under perennial single cropping of tobacco. In recent years, the rotation of tobacco-radish has gradually become popular.
Yuhao Dai   +10 more
doaj   +1 more source

Ganoderma lucidum polysaccharide inhibits LPS-induced inflammatory injury to mammary epithelial cells

open access: yesJournal of Future Foods, 2023
This study sought to investigate whether Ganoderma lucidum polysaccharide (GLP) has a protective effect on lipopolysaccharide (LPS)-induced inflammatory injury to mammary epithelial HC-11 cells and to characterize the mechanism involved.
Yi Fan   +7 more
doaj  

Antitumor Activity of Asperphenin A, a Lipopeptidyl Benzophenone from Marine-Derived Aspergillus sp. Fungus, by Inhibiting Tubulin Polymerization in Colon Cancer Cells

open access: yesMarine Drugs, 2020
Marine-derived microorganisms are a valuable source of novel bioactive natural products. Asperphenin A is a lipopeptidyl benzophenone metabolite isolated from large-scale cultivation of marine-derived Aspergillus sp. fungus. The compound has shown potent
Song Yi Bae   +5 more
doaj   +1 more source

Natural Products and Cancer

open access: yesNutrients, 2023
Natural and dietary compounds are known to offer protection and affect the pathogeneses of numerous chronic diseases [...]
openaire   +2 more sources

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