Results 11 to 20 of about 4,178,100 (256)
GPX8 regulates clear cell renal cell carcinoma tumorigenesis through promoting lipogenesis by NNMT
Journal of Experimental & Clinical Cancer Research, 2023 Background Clear cell renal cell carcinoma (ccRCC), with its hallmark phenotype of high cytosolic lipid content, is considered a metabolic cancer. Despite the implication of this lipid-rich phenotype in ccRCC tumorigenesis, the roles and regulators of de
Tin Tin Manh Nguyen +11 more
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Natural Products for Medicine [PDF]
Journal of Biomedicine and Biotechnology, 2012 Throughout human history, natural products—including terrestrial plants, animal products, marine organisms, and products of microorganismal fermentation—have been used in traditional medicines. This historical experience with natural products as therapeutic agents has evolved to sophisticated isolation of active chemical entities from ...
Masa-Aki Shibata +3 more
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Antioxidants, 2022 With the recent development of chemical analysis technology, attention has been placed on natural light-sensitive compounds that exhibit photoreactivity to expand the structural diversity of natural product chemistry. Photochemical reactions that proceed
InWha Park +6 more
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Bioactive Natural Products [PDF]
Journal of Chemistry, 2013 Bioactive natural products have never ceased to play an important role in the search of novel therapeutic agents. Natural products from the nature such as the plant and marine sources form an integral part of the living system, and they have existed ever since the beginning of life.Therefore, it is undeniable that works related to natural products ...
Ana Belen Martin-Diana +2 more
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Dithiolopyrrolone Natural Products : Isolation, Synthesis and Biosynthesis [PDF]
, 2013 Peer reviewedPublisher ...
Deng, Hai +3 more
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BMC Bioinformatics, 2020 Background Despite continued efforts using chemical similarity methods in virtual screening, currently developed approaches suffer from time-consuming multistep procedures and low success rates.
Prasannavenkatesh Durai +3 more
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Biosynthesis of thiocarboxylic acid-containing natural products. [PDF]
, 2018 Thiocarboxylic acid-containing natural products are rare and their biosynthesis and biological significance remain unknown. Thioplatensimycin (thioPTM) and thioplatencin (thioPTN), thiocarboxylic acid congeners of the antibacterial natural products ...
Deng, Youchao +9 more
core +1 more source
Nat. Prod. Rep., 2012 This review of marine natural products for 2014 describes 1378 new compounds and reports structural revisions or assignments of absolute configuration for previously reported compounds. Since 1965 MNP chemists have made ∼9000 collections worldwide yielding ∼25 700 new MNPs. The rate of discovery of MNPs by region is examined in this review.
John W. Blunt +4 more
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Antiplasmodial Natural Products [PDF]
Molecules, 2011 Malaria is a human infectious disease that is caused by four species of Plasmodium. It is responsible for more than 1 million deaths per year. Natural products contain a great variety of chemical structures and have been screened for antiplasmodial activity as potential sources of new antimalarial drugs.
Nogueira, Claudio R. +1 more
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Novel Thioethers of Dihydroartemisinin Exhibiting Their Biological Activities
Heteroatom Chemistry, 2023 Eleven conjugates between dihydroartemisinin (DHA) with thiols containing both ether and thioether bonds were designed, synthesized by a two-step procedure including etherification and S-alkylation.
Ngoc Hung Truong +6 more
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