Results 11 to 20 of about 4,373,264 (365)
GPX8 regulates clear cell renal cell carcinoma tumorigenesis through promoting lipogenesis by NNMT
Journal of Experimental & Clinical Cancer Research, 2023 Background Clear cell renal cell carcinoma (ccRCC), with its hallmark phenotype of high cytosolic lipid content, is considered a metabolic cancer. Despite the implication of this lipid-rich phenotype in ccRCC tumorigenesis, the roles and regulators of de
Tin Tin Manh Nguyen +11 more
doaj +1 more source
Multi-Omic Profiling of Melophlus Sponges Reveals Diverse Metabolomic and Microbiome Architectures that Are Non-overlapping with Ecological Neighbors. [PDF]
, 2020 Marine sponge holobionts, defined as filter-feeding sponge hosts together with their associated microbiomes, are prolific sources of natural products. The inventory of natural products that have been isolated from marine sponges is extensive. Here, using
Agarwal, Vinayak +5 more
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Pseudo Natural Products—Chemical Evolution of Natural Product Structure [PDF]
Angewandte Chemie International Edition, 2021 AbstractPseudo‐natural products (PNPs) combine natural product (NP) fragments in novel arrangements not accessible by current biosynthesis pathways. As such they can be regarded as non‐biogenic fusions of NP‐derived fragments. They inherit key biological characteristics of the guiding natural product, such as chemical and physiological properties, yet ...
Luca Laraia +7 more
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Antioxidants, 2022 With the recent development of chemical analysis technology, attention has been placed on natural light-sensitive compounds that exhibit photoreactivity to expand the structural diversity of natural product chemistry. Photochemical reactions that proceed
InWha Park +6 more
doaj +1 more source
Natural Products for Medicine [PDF]
Journal of Biomedicine and Biotechnology, 2012 Throughout human history, natural products—including terrestrial plants, animal products, marine organisms, and products of microorganismal fermentation—have been used in traditional medicines. This historical experience with natural products as therapeutic agents has evolved to sophisticated isolation of active chemical entities from ...
Masa-Aki Shibata +3 more
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Bioactive Natural Products [PDF]
Journal of Chemistry, 2013 Bioactive natural products have never ceased to play an important role in the search of novel therapeutic agents. Natural products from the nature such as the plant and marine sources form an integral part of the living system, and they have existed ever since the beginning of life.Therefore, it is undeniable that works related to natural products ...
Ana Belen Martin-Diana +2 more
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BMC Bioinformatics, 2020 Background Despite continued efforts using chemical similarity methods in virtual screening, currently developed approaches suffer from time-consuming multistep procedures and low success rates.
Prasannavenkatesh Durai +3 more
doaj +1 more source
Einstein metrics on conformal products [PDF]
Annals of Global Analysis and Geometry 65, article 20 (2024), 2023 We show that under some natural geometric assumption, Einstein metrics on conformal products of two compact conformal manifolds are warped product metrics.
arxiv +1 more source
Biosynthesis of thiocarboxylic acid-containing natural products. [PDF]
, 2018 Thiocarboxylic acid-containing natural products are rare and their biosynthesis and biological significance remain unknown. Thioplatensimycin (thioPTM) and thioplatencin (thioPTN), thiocarboxylic acid congeners of the antibacterial natural products ...
Deng, Youchao +9 more
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