Results 21 to 30 of about 4,373,264 (365)
This review of marine natural products for 2014 describes 1378 new compounds and reports structural revisions or assignments of absolute configuration for previously reported compounds. Since 1965 MNP chemists have made ∼9000 collections worldwide yielding ∼25 700 new MNPs. The rate of discovery of MNPs by region is examined in this review.
John W. Blunt+4 more
openaire +15 more sources
Physalin A regulates the Nrf2 pathway through ERK and p38 for induction of detoxifying enzymes
Background Physalin A isolated from Physalis alkekengi var. franchetii has been known to have many pharmacological properties. However, its effect through the Nrf2 pathway has not yet been elucidated.
Ji Min Shin+4 more
doaj +1 more source
Novel Thioethers of Dihydroartemisinin Exhibiting Their Biological Activities
Eleven conjugates between dihydroartemisinin (DHA) with thiols containing both ether and thioether bonds were designed, synthesized by a two-step procedure including etherification and S-alkylation.
Ngoc Hung Truong+6 more
doaj +1 more source
Dithiolopyrrolone Natural Products : Isolation, Synthesis and Biosynthesis [PDF]
Peer reviewedPublisher ...
Deng, Hai+3 more
core +2 more sources
A comprehensive review of 1554 new MNPs, including numerous novel and bioactive compounds from marine bacteria.
Anthony R. Carroll+4 more
openaire +12 more sources
Antiplasmodial Natural Products [PDF]
Malaria is a human infectious disease that is caused by four species of Plasmodium. It is responsible for more than 1 million deaths per year. Natural products contain a great variety of chemical structures and have been screened for antiplasmodial activity as potential sources of new antimalarial drugs.
Nogueira, Claudio R.+1 more
openaire +4 more sources
Background Circaea mollis Sieb. & Zucc. has been used as a traditional herbal medicine in Hani Ethnopharmacy and possesses anti-arthritic activities.
Ji Hye Park+4 more
doaj +1 more source
Aryne Acyl-Alkylation in the General and Convergent Synthesis of Benzannulated Macrolactone Natural Products: An Enantioselective Synthesis of (−)-Curvularin [PDF]
A general approach for the synthesis of benzannulated macrolactone natural products utilizing an aryne acyl-alkylation reaction is described. Toward this end, the total syntheses of the natural products (−)-curvularin, curvulin, and (−)-diplodialide C ...
Stoltz, Brian M.+2 more
core +2 more sources
Natural Products for Antithrombosis [PDF]
Thrombosis is considered to be closely related to several diseases such as atherosclerosis, ischemic heart disease and stroke, as well as rheumatoid arthritis, hyperuricemia, and various inflammatory conditions. More and more studies have been focused on understanding the mechanism of molecular and cellular basis of thrombus formation as well as ...
Cen Chen+5 more
openaire +2 more sources
Utilization of waste-derived materials for industrially pertinent chemical transformations is highly challenging and offers sustainable solution to waste management.
Rama Moorthy Appa+6 more
doaj +1 more source