Results 71 to 80 of about 5,415,293 (346)
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
iScienceSummary: The side-firing instrument is studied under the complete bevel angle range. The fiber core and cladding are 0.6 mm and 0.66 mm, respectively, the fiber core refractive index is 1.457, and the fiber cladding refractive index is from 1.409 to 1 ...
Diqing Ying
doaj +1 more source
Natural history and community science records confirm rapid geographic shifts in the distribution of Bachman’s Sparrow (Peucaea aestivalis) since 1850 [PDF]
, 2022 Amie E. Settlecowski +4 more
openalex +1 more source
Households without Houses : Mobility and Moorings on the Eurasian Steppe [PDF]
, 2016 The research that provided the basis for this paper was carried out in collaboration with the Institutes of History and Archaeology of the Mongolian Academy of Sciences and would not have been possible without my colleagues Chunag Amartuvshin, William ...
Wright, Joshua
core +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
iScienceSummary: Pyrrolidine (PyD) has an important impact on the environment and human health. However, there is currently no method for trace detection of PyD. Here, we successfully designed diaminomethylene-4H-pyran (1) as the first specific fluorescent probe
Xi-Ying Cao +9 more
doaj +1 more source
PEDAGOGICAL POTENTIAL OF THE EDUCATIONAL PROCESS IN STIMULATING A POSITIVE AND ACTIVE ATTITUDE TO THE ENRICHMENT OF BIOLOGY COMPETENCE OF FUTURE BACHELORS OF NATURAL SCIENCES [PDF]
, 2023 Nadiia Gramatyk
openalex +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
iScienceSummary: Dengue virus (DENV) is a mosquito-transmitted flavivirus; there are four serotypes (DENV1-4) that co-circulate globally. Primary infection causes self-limiting febrile illness, but secondary infection by a heterologous serotype can predispose to
Margarette C. Mariano +10 more
doaj +1 more source