Developing therapeutic strategies to target MCL1 and BCLXL in lethal prostate cancer. [PDF]
Westaby D +26 more
europepmc +1 more source
Correspondance: Venetoclax combined with FLAG-based chemotherapy induces rapid and deep responses in early T-cell precursor lymphoblastic leukemia/lymphoma. Report of two cases and review of the literature. [PDF]
Dereme J +6 more
europepmc +1 more source
A phase 1 study of the combination of BH3-mimetic, navitoclax, and mTORC1/2 inhibitor, vistusertib, in patients with advanced solid tumors. [PDF]
Scott SC +11 more
europepmc +1 more source
Moving forward from spleen response as an endpoint in randomized controlled trials in myelofibrosis. [PDF]
Van Dijck R +2 more
europepmc +1 more source
<i>In silico</i> evaluation of vitamin D3 as a dual inhibitor of CDK2 and Bcl-2 in colorectal cancer. [PDF]
Shobahah J +4 more
europepmc +1 more source
The Yin and Yang of cellular senescence in ischemia-induced myocardial injury. [PDF]
Wolff von Gudenberg R +6 more
europepmc +1 more source
A Macrophage-Derived 7-Gene Signature Predicts Prognosis and Therapeutic Response in Hepatocellular Carcinoma. [PDF]
Li X, Li Z, Zhai J, Zou B.
europepmc +1 more source
Related searches:
Senolytic Agent Navitoclax Inhibits Angiotensin II-Induced Heart Failure in Mice
Journal of Cardiovascular Pharmacology, 2020Abstract: Navitoclax, which is a type of senolytic drug, selectively eliminates senescent cells. This study aimed to evaluate the therapeutic potential of navitoclax in treatment of angiotensin II (Ang II)-induced heart failure in mice. Navitoclax or vehicle was administrated in mice with Ang II-induced heart failure.
Kangni Jia, Ao Liu, Lin Lu
exaly +3 more sources

