Results 1 to 10 of about 20,747 (199)

Niclosamide-loaded nanoparticles (Ncl-NPs) reverse pulmonary fibrosis in vivo and in vitro

open access: yesJournal of Advanced Research, 2023
Introduction: Idiopathic pulmonary fibrosis (IPF), a life-threatening interstitial lung disease, is characterized by excessive activation and proliferation of fibroblasts and epithelial-mesenchymal transition (EMT) of alveolar epithelial cells (AEC ...
Liang Ouyang   +2 more
exaly   +3 more sources

Human pathology in NCL

open access: yesBiochimica Et Biophysica Acta - Molecular Basis of Disease, 2013
In childhood the neuronal ceroid lipofuscinoses (NCL) are the most frequent lysosomal diseases and the most frequent neurodegenerative diseases but, in adulthood, they represent a small fraction among the neurodegenerative diseases. Their morphology is marked by: (i) loss of neurons, foremost in the cerebral and cerebellar cortices resulting in ...
Alessandro Simonati
exaly   +3 more sources

A rewriting logic semantics for NCL

open access: yesScience of Computer Programming, 2015
The Nested Context Language (NCL) is a multimedia authoring language that is part of the standard for digital television in Brazil and in Latin America and the ITU standard for IPTV services. To properly support authors in the development of NCL applications, it is important to provide tools with validation capabilities.
Joel Dos Santos   +2 more
exaly   +2 more sources

Effect of Suction on Volumetric Yielding Behavior under Different Initial Conditions for Fine-Grained Soils [PDF]

open access: yesEngineering and Technology Journal, 2013
The unsaturated soils are difficult to consider within the framework of classical (saturated) soil mechanics. In general, the unsaturated soil is stiffer than the saturated one (hardening), so the location and slope of normal consolidated line (NCL) or ...
Yasir Al-Badran, Tom Schanz
doaj   +1 more source

Investigation of Crack in Beam Structure using an Adaptive-Genetic Algorithm (AGA)

open access: yesU.Porto Journal of Engineering, 2022
Fault detection and continuous condition monitoring in structural and machine elements are very sensitive topics and gaining significant value as a current research area. Due to the continuous loading and unloading of these elements, fatigue occurs.
SASMITA SAHU, SHAKTI JENA
doaj   +1 more source

G-protein coupled receptor, PI3K and Rho signaling pathways regulate the cascades of Tau and amyloid-β in Alzheimer’s disease

open access: yesMolecular Biomedicine, 2021
Alzheimer’s disease is a progressive neurodegenerative disease characterized by the presence of amyloid-β plaques in the extracellular environment and aggregates of Tau protein that forms neurofibrillary tangles (NFTs) in neuronal cells. Along with these
Smita Eknath Desale   +2 more
doaj   +1 more source

Correlations between structure, microstructure, density and dielectric properties of the lead-free ferroelectrics Bi0.5(Na,K)0.5TiO3 [PDF]

open access: yesJournal of Advanced Dielectrics, 2015
Solid solutions of the lead-free ferroelectric oxides Bi0.5Na0.5TiO3 (BNT) and Bi0.5K0.5TiO3 (BKT), represented as (1−x)BNT–xBKT, are studied for very close compositions in the range 0≤x≤0.36 to understand the correlation between the structure and the ...
K. Anjali, T. G. Ajithkumar, P. A. Joy
doaj   +1 more source

The extracellular HDAC6 ZnF UBP domain modulates the actin network and post-translational modifications of Tau

open access: yesCell Communication and Signaling, 2021
Background Microtubule-associated protein Tau undergoes aggregation in Alzheimer`s disease (AD) and a group of other related diseases collectively known as Tauopathies.
Abhishek Ankur Balmik   +2 more
doaj   +1 more source

Impact of cloud parameterization on the numerical simulation of a super cyclone [PDF]

open access: yesAnnales Geophysicae, 2012
This study examines the role of parameterization of convection and explicit moisture processes on the simulated track, intensity and inner core structure of Orissa super cyclone (1999) in Bay of Bengal (north Indian Ocean). Sensitivity experiments are
M. S. Deshpande   +2 more
doaj   +1 more source

Expression of transduced nucleolin promotes the clearance of accumulated α-synuclein in rodent cells and animal model

open access: yesNeurobiology of Disease, 2021
Alpha-synuclein (αSyn) is a major component of Lewy bodies, which are a known pathogenic marker of Parkinson's disease (PD). The dysfunction of protein degradation machinery causes αSyn accumulation.
Dong Hwan Ho   +6 more
doaj   +1 more source

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