Results 31 to 40 of about 25,091 (203)

NCL-WT and 6/S*A interact with endogenous NCL.

open access: yes, 2014
Nuclear extracts (NE) were prepared from cells grown without Dx for at least 10 d for NCL-WT or 6/S*A expression. Ctrl represents control cells without exogenous NCL expression.
Xin Li (51274)   +8 more
core   +1 more source

Blockage of Orai1-Nucleolin interaction meditated calcium influx attenuates breast cancer cells growth

open access: yesOncogenesis, 2022
As an important second messenger, calcium (Ca2+) regulates a wide variety of physiological processes. Disturbance of intracellular calcium homeostasis implicated in the occurrence of multiple types of diseases.
Chunming Gu   +9 more
doaj   +1 more source

One dimensional normal consolidation line equation

open access: yesJournal of the Mechanical Behavior of Materials, 2022
Many empirical equations have been proposed in the past to predict the parameters of the one-dimensional normal consolidation line (1D-NCL) for soils. However, applications of these equations are limited to specific range of pressure and plasticity soils.
Al-Badran Yasir M.   +2 more
doaj   +1 more source

A Computational Strategy for Identifying Self‐Assembling Food‐Derived Molecules for Antiparasitic Nanotherapy

open access: yesAdvanced Science, EarlyView.
An integrated computational screening strategy identified ursolic acid (UA) and 18β‐glycyrrhetinic acid (18βGA) as a self‐assembling food‐derived molecular pair. The resulting carrier‐free nanoparticles (UA‐18βGA) showed synergistic antiparasitic activity, reduced combined toxicity, and host‐protective anti‐inflammatory effects in zebrafish and murine ...
Shenye Qu   +8 more
wiley   +1 more source

Study on Influencing Factors Analysis of Gastric Tube Insertion Length and Construction of Estimation Method

open access: yesFrontiers in Surgery, 2022
BackgroundInfluenced by individual differences, the depth of gastric tube placement is often different. Clinically, it is necessary to seek a simple and accurate gastric tube insertion scheme to improve the clinical efficacy of indwelling gastric tube ...
Hua Zhang   +6 more
doaj   +1 more source

Heterointerface Engineering of Bismuth Nanosheets/Nitrogen‐Doped Carbon Nanoleaves Enables High‑Performance Electrochemical Dechlorination

open access: yesAdvanced Science, EarlyView.
Bismuth nanosheets integrated with nitrogen‐doped carbon nanoleaves are constructed via a 2D‐on‐2D heterointerface engineering strategy. The resulting BiNS/NCL electrode delivers high chloride adsorption capacity, fast kinetics, and stable cyclability. A built‐in electric field at the heterointerface promotes chloride electrosorption and stabilizes the
Bohan Liu   +11 more
wiley   +1 more source

Induced expression of nucleolin phosphorylation-deficient mutant confers dominant-negative effect on cell proliferation.

open access: yesPLoS ONE, 2014
Nucleolin (NCL) is a major nucleolar phosphoprotein that has pleiotropic effects on cell proliferation and is elevated in a variety of tumors. NCL is highly phosphorylated at the N-terminus by two major kinases: interphase casein kinase 2 (CK2) and ...
Shu Xiao   +8 more
doaj   +1 more source

A one base pair deletion in the canine ATP13A2 gene causes exon skipping and late-onset neuronal ceroid lipofuscinosis in the Tibetan terrier. [PDF]

open access: yesPLoS Genetics, 2011
Neuronal ceroid lipofuscinosis (NCL) is a progressive neurodegenerative disease characterized by brain and retinal atrophy and the intracellular accumulation of autofluorescent lysosomal storage bodies resembling lipofuscin in neurons and other cells ...
Anne Wöhlke   +6 more
doaj   +1 more source

Pathogen‐Centric Activation of an Azoreductase‐Responsive Antibody‐Antibiotic Conjugate for the Targeted Eradication of MRSA

open access: yesAdvanced Science, EarlyView.
A pathogen‐centric antibody‐antibiotic conjugate (AZO‐AAC) releases antibiotics via bacterial azoreductase, independent of host‐lysosomal function. This mechanism achieves nanomolar eradication of both planktonic and intracellular methicillin‐resistant Staphylococcus aureus (MRSA).
Qi Cheng   +13 more
wiley   +1 more source

Silk fibroin micro-particle scaffolds with superior compression modulus and slow bioresorption for effective bone regeneration

open access: yesScientific Reports, 2018
Silk fibroin (SF), a natural polymer produced by Bombyx mori silkworms, has been extensively explored to prepare porous scaffolds for tissue engineering applications.
Anuya Nisal   +7 more
doaj   +1 more source

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