Results 21 to 30 of about 35,363 (287)

The extracellular HDAC6 ZnF UBP domain modulates the actin network and post-translational modifications of Tau

open access: yesCell Communication and Signaling, 2021
Background Microtubule-associated protein Tau undergoes aggregation in Alzheimer`s disease (AD) and a group of other related diseases collectively known as Tauopathies.
Abhishek Ankur Balmik   +2 more
doaj   +1 more source

Impact of cloud parameterization on the numerical simulation of a super cyclone [PDF]

open access: yesAnnales Geophysicae, 2012
This study examines the role of parameterization of convection and explicit moisture processes on the simulated track, intensity and inner core structure of Orissa super cyclone (1999) in Bay of Bengal (north Indian Ocean). Sensitivity experiments are
M. S. Deshpande   +2 more
doaj   +1 more source

Expression of transduced nucleolin promotes the clearance of accumulated α-synuclein in rodent cells and animal model

open access: yesNeurobiology of Disease, 2021
Alpha-synuclein (αSyn) is a major component of Lewy bodies, which are a known pathogenic marker of Parkinson's disease (PD). The dysfunction of protein degradation machinery causes αSyn accumulation.
Dong Hwan Ho   +6 more
doaj   +1 more source

Photoelectron Photoion Coincidence Spectroscopy of NCl\(_{3}\) and NCl\(_{2}\)

open access: yes, 2021
We investigate NCl\(_{3}\) and the NCl\(_{2}\) radical by photoelectron-photoion coincidence spectroscopy using synchrotron radiation. The mass selected threshold photoelectron spectrum (ms-TPES) of NCl\(_{3}\) is broad and unstructured due to the large ...
Ingo Fischer   +13 more
core   +1 more source

Présentation de l'élevage aux îles Wallis et Futuna

open access: yesRevue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1987
Les îles Wallis et Futuna, Territoire français d'Outre-Mer situé dans le Pacifique Sud, possèdent depuis 1980 une antenne vétérinaire IEMVT. Après une description générale du territoire, sont décrits les principales espèces domestiques (porcs, volailles,
P. Giraud   +3 more
doaj   +1 more source

Phagocytosis of full-length Tau oligomers by Actin-remodeling of activated microglia

open access: yesJournal of Neuroinflammation, 2020
Background Alzheimer’s disease is associated with the accumulation of intracellular Tau tangles within neurons and extracellular amyloid-β plaques in the brain parenchyma, which altogether results in synaptic loss and neurodegeneration.
Rashmi Das   +2 more
doaj   +1 more source

Phosphoinositides signaling modulates microglial actin remodeling and phagocytosis in Alzheimer’s disease

open access: yesCell Communication and Signaling, 2021
Alzheimer’s disease is one of the neurodegenerative diseases, characterized by the accumulation of abnormal protein deposits, which disrupts signal transduction in neurons and other glia cells.
Smita Eknath Desale   +1 more
doaj   +1 more source

Composition chimique et dégradabilité enzymatique et in vitro d'espèces ligneuses arbustives utilisables par les ruminants dans les parcours extensifs de la Nouvelle Calédonie. I. Typologie

open access: yesRevue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1996
Cette étude, réalisée sur 45 espèces arbustives récoltées en Nouvelle Calédonie, a permis de mettre en évidence six groupes de ligneux fourragers caractérisés par leurs teneurs en éléments bruts et leurs dégradabilités enzymatiques et in vitro.
Christian Corniaux   +3 more
doaj   +1 more source

Hepatocellular Carcinoma in Non-cirrhotic Liver Arises with a More Advanced Tumoral Appearance: A Single-Center Cohort Study

open access: yesThe Turkish Journal of Gastroenterology, 2021
Background: A small proportion of all hepatocellular carcinomas (HCCs) arise in a non-cirrhotic liver (NCL). However, our knowledge about the HCCs developing in a NCL is scarce.
Coşkun Özer Demirtaş   +4 more
doaj   +1 more source

NAFLD‐related hepatocellular carcinoma: The growing challenge

open access: yesHepatology, EarlyView., 2022
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah   +2 more
wiley   +1 more source

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