Results 151 to 160 of about 2,604,331 (176)

Near-infrared photoimmunotherapy targeting Nectin-4 in a preclinical model of bladder cancer. [PDF]

open access: yesCancer Lett
Fukushima H   +9 more
europepmc   +1 more source

Near-Infrared Photoimmunotherapy (NIR-PIT) in Urologic Cancers

open access: yesCancers, 2022
Near-infrared photoimmunotherapy (NIR-PIT) is a novel molecularly-targeted therapy that selectively kills cancer cells by systemically injecting an antibody-photoabsorber conjugate (APC) that binds to cancer cells, followed by the application of NIR light that drives photochemical transformations of the APC.
Peter A Pinto   +2 more
exaly   +4 more sources

Near Infrared Photoimmunotherapy; A Review of Targets for Cancer Therapy [PDF]

open access: yesCancers, 2021
Near-infrared photoimmunotherapy (NIR-PIT) is a newly developed cancer treatment that uses an antibody-photoabsorber (IRDye700DX) conjugate (APC) that is activated by NIR light irradiation. In September 2020, the first APC and laser system were conditionally approved for clinical use in Japan.
Hiroaki Wakiyama   +2 more
exaly   +3 more sources

Near-infrared photoimmunotherapy and anti-cancer immunity

International Immunology, 2023
Abstract The activation of the anti-cancer immune system is an important strategy to control cancer. A new form of cancer phototherapy, near-infrared photoimmunotherapy (NIR-PIT), was approved for clinical use in 2020 and uses IRDye® 700DX (IR700)-conjugated antibodies and NIR light.
Kohei Nakajima, Mikako Ogawa
openaire   +2 more sources

Near-infrared photoimmunotherapy for the treatment of skin disorders

Expert Opinion on Biological Therapy, 2021
Near-Infrared Photoimmunotherapy (NIR-PIT) is a novel molecularly targeted phototherapy. This technique is based on a conjugate of a near-infrared photo-inducible molecule (antibody-photon absorber conjugate, APC) and a monoclonal antibody that targets a tumor-specific antigen. To date, this novel approach has been successfully applied to several types
Russo I   +5 more
openaire   +3 more sources

PD-L1 near Infrared Photoimmunotherapy of Ovarian Cancer Model [PDF]

open access: yesCancers, 2022
(1) Background: Despite advances in surgical approaches and drug development, ovarian cancer is still a leading cause of death from gynecological malignancies. Patients diagnosed with late-stage disease are treated with aggressive surgical resection and chemotherapy, but recurrence with resistant disease is often observed following treatment.
Balaji Krishnamachary   +2 more
exaly   +3 more sources

Near Infrared Photoimmunotherapy for Mouse Models of Pleural Dissemination

Journal of Visualized Experiments, 2021
The efficacy of photoimmunotherapy can be evaluated more accurately with an orthotopic mouse model than with a subcutaneous one. A pleural dissemination model can be used for the evaluation of treatment methods for intrathoracic diseases such as lung cancer or malignant pleural mesothelioma.
Hirotoshi, Yasui   +5 more
openaire   +2 more sources

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