Results 291 to 300 of about 60,497 (319)

PANoptosis: a potential target of cardiomyopathy. [PDF]

open access: yesFront Immunol
Sun M, Lu C, Wei J, Gao C, Dong D.
europepmc   +1 more source

Necroptosis in atherosclerosis

Clinica Chimica Acta, 2022
Atherosclerosis, a chronic inflammatory disease, is a leading cause of death worldwide. Vascular endothelial cells (VECs), vascular smooth muscle cells (VSMCs) and macrophages play extremely vital roles in the formation of atherosclerotic plaques and subsequent atherosclerosis.
Xiaofan, Zhang   +3 more
openaire   +2 more sources

Necroptosis pathways in tumorigenesis

Seminars in Cancer Biology, 2022
Necroptosis is a caspase-independent form of programmed cell death executed by the receptor interacting protein kinase 1 (RIPK1)-RIPK3-mixed lineage kinase domain-like protein (MLKL) signaling cascade, deregulation of which can cause various human diseases including cancer.
Tao, Zhang   +3 more
openaire   +2 more sources

Apoptosis, Pyroptosis, and Necroptosis-Oh My! The Many Ways a Cell Can Die.

Journal of Molecular Biology, 2021
Cell death is an essential process in all living organisms and occurs through different mechanisms. The three main types of programmed cell death are apoptosis, pyroptosis, and necroptosis, and each of these pathways employs complex molecular and ...
Natália Ketelut-Carneiro, K. Fitzgerald
semanticscholar   +1 more source

Necroptosis at a glance

Journal of Cell Science, 2022
ABSTRACT Necroptosis, or programmed necrosis, is an inflammatory form of cell death with important functions in host defense against pathogens and tissue homeostasis. The four cytosolic receptor-interacting protein kinase homotypic interaction motif (RHIM)-containing adaptor proteins RIPK1, RIPK3, TRIF (also known as TICAM1) and ZBP1 ...
Kidong Kang   +2 more
openaire   +2 more sources

Necroptosis and Inflammation

Annual Review of Biochemistry, 2016
Necroptosis is a regulated form of necrosis, with the dying cell rupturing and releasing intracellular components that can trigger an innate immune response. Toll-like receptor 3 and 4 agonists, tumor necrosis factor, certain viral infections, or the T cell receptor can trigger necroptosis if the activity of the protease caspase-8 is compromised ...
Kim, Newton, Gerard, Manning
openaire   +2 more sources

Home - About - Disclaimer - Privacy