Results 91 to 100 of about 39,640 (202)

HIV-1 nef suppression by virally encoded microRNA

Retrovirology, 2004
Background MicroRNAs (miRNAs) are 21~25-nucleotides (nt) long and interact with mRNAs to trigger either translational repression or RNA cleavage through RNA interference (RNAi), depending on the degree of complementarity with the target mRNAs. Our recent
Brisibe Ebiamadon, Okuyama Harumi, Ichikawa Yuko, Tsutsumi Yutaka, Ito Masafumi, Omoto Shinya, Saksena Nitin K, Fujii Yoichi R   +7 more
doaj   +1 more source

nef-deleted HIV-1 inhibits phagocytosis by monocyte-derived macrophages in vitro but not by peripheral blood monocytes in vivo

, 2001
nef-deleted HIV-1 inhibits phagocytosis by monocyte-derived macrophages in vitro but not by peripheral blood monocytes in ...
H Chan (7732445), A Violo (13728565), J Hocking (13312737), J Mills (7665794), S Crowe (13428231), D Purcell (13728568), K Kedzierska (9863357), A Jaworowski (9684227), Johnson Mak (13082904), A Greenway (13711348), J Sullivan (9852734)   +10 more
core  

Sleep characteristics and self‐reported sleep quality in the oldest‐old: Results from a prospective longitudinal cohort study

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Little is known about the correlation between subjective perception and objective measures of sleep quality in particular in the oldest‐old. The aim of this study was to perform longitudinal home sleep monitoring in this age group, and to correlate results with self‐reported sleep quality.
Hugo Saner, Kevin Möri, Narayan Schütz, Philipp Buluschek, Tobias Nef   +4 more
wiley   +1 more source

Molecular Chaperone Networks in Plants: Maintaining Proteostasis and Enhancing Stress Resilience for Crop Improvement

Plant, Cell &Environment, EarlyView.
ABSTRACT Molecular chaperones play a central role in the plant proteostasis machinery by aiding the folding of nascent proteins, preventing aggregation, and repairing or degrading damaged proteins. These functions are especially essential during abiotic and biotic stress, which can destabilise cellular proteins and disrupt metabolic homoeostasis.
Mingfang Yang, Anqin Gao, Tsz‐Yan Chan, Hafiz Mamoon Rehman, Sehar Nawaz, Sehrish Bashir, Noman Mahmood, Muhammad Wajid Ullah, Chunlin Long, Hon‐Ming Lam, Muhammad Arif   +10 more
wiley   +1 more source

Solution Synthesis of Actinide Chalcogenide and Oxychalcogenide Nanoparticles

Angewandte Chemie, Volume 138, Issue 36, 1 September 2026.
We report the synthesis of UOS, UOSe, and US2 nanoparticles under colloidal conditions. The magnetic properties were measured of all three materials and compared to prior studies of UO2 nanoparticles. Nanoparticle phases were determined using powder diffraction, and size by transmission electron microscopy.
Cheyenne Orozco, Orlando C. Stewart Jr., Nicole Vanagas, Greg Morrison, Hans‐Conrad zur Loye, Hope E. Smith, Karah Knope, Sarah L. Stoll   +7 more
wiley   +2 more sources

LncRNA-NEF is downregulated in postmenopausal osteoporosis and is related to course of treatment and recurrence

Journal of International Medical Research, 2019
Objectives We investigated the role of long non-coding (lnc) RNA-NEF (neighboring enhancer of FoxA2), a characterized oncogene in cancer biology, in postmenopausal osteoporosis and its diagnostic and prognostic value in this disease.
Xiaoyong Ma, Zhixue Guo, Wenshan Gao, Jianzhong Wang, Yong Liu, Fei Gao, Shaosong Sun, Xiaozhe Zhou, Zhaoyu Yang, Wenkui Zheng   +9 more
doaj   +1 more source

Relative Resistance of HLA-B to Downregulation by Naturally Occurring HIV-1 Nef Sequences

mBio, 2016
HIV-1 Nef binds to the cytoplasmic region of HLA-A and HLA-B and downregulates these molecules from the surface of virus-infected cells, thus evading immune detection by CD8+ T cells.
Macdonald Mahiti, Mako Toyoda, Xiaofei Jia, Xiaomei T. Kuang, Francis Mwimanzi, Philip Mwimanzi, Bruce D. Walker, Yong Xiong, Zabrina L. Brumme, Mark A. Brockman, Takamasa Ueno   +10 more
doaj   +1 more source

ARF1 Regulates Nef-Induced CD4 Degradation [PDF]

, 2004
Background: The HIV Nef protein downregulates CD4 through sequential connection with clathrin-coated pits and the COP1 coatomer, resulting in accelerated endocytosis and lysosomal targeting.Results: Here we report that the small GTPase ARF1 controls the ...
Borel, Christelle, Sobo, Komla, Trono, Didier, Piguet, Vincent, Demaurex, Nicolas, Stalder Monney, Romaine, Stalder, Romaine, Gruenberg, Jean, Fauré, Julien   +8 more
core   +1 more source

The Chaetocerosphere: Chaetoceros Species and Associated Prokaryotes in a Coastal Area

Environmental Microbiology Reports, Volume 18, Issue 5, October 2026.
Chaetoceros species maintain recurrent distinct prokaryotic assemblages in their phycosphere. Alphaproteobacteria, Bacteroidetes and Archaea Thermoplasmata and Marine Group II are the most represented in the phycosphere. Bipartite networks highlight strong links between the diatom and specific prokaryotic taxa, especially the chain‐forming species ...
Anna Chiara Trano, Raffaella Casotti, Roberta Piredda   +2 more
wiley   +1 more source

HIV-1 Nef binds the DOCK2-ELMO1 complex to activate rac and inhibit lymphocyte chemotaxis.

PLoS Biology, 2004
The infectious cycle of primate lentiviruses is intimately linked to interactions between cells of the immune system. Nef, a potent virulence factor, alters cellular environments to increase lentiviral replication in the host, yet the mechanisms ...
Ajit Janardhan, Tomek Swigut, Brian Hill, Michael P Myers, Jacek Skowronski   +4 more
doaj   +1 more source