Results 101 to 110 of about 39,640 (202)
Logique et ontologie des objets sociaux [PDF]
, 2015 Frédéric Nef, directeur d’études Compte rendu non ...
Nef, Frederic
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Direct binding to GABARAP family members is essential for HIV-1 Nef plasma membrane localization
Scientific Reports, 2017 HIV-1 Nef is an important pathogenic factor for HIV/AIDS pathogenesis. Studies have shown that the association of Nef with the inner leaflet of the plasma membrane and with endocytic and perinuclear vesicles is essential for most activities of Nef. Using
Alexandra Boeske +8 more
doaj +1 more source
How HIV-1 Nef hijacks the AP-2 clathrin adaptor to downregulate CD4
eLife, 2014 The Nef protein of HIV-1 downregulates the cell surface co-receptor CD4 by hijacking the clathrin adaptor complex AP-2. The structural basis for the hijacking of AP-2 by Nef is revealed by a 2.9 Å crystal structure of Nef bound to the α and σ2 subunits ...
Xuefeng Ren +3 more
doaj +1 more source
, 2002 International audienceThe nef genes of human and simian immunodeficiency viruses code for a membrane associated protein critical for AIDS development. SIVmac Nef presents C-terminal a 27 amino acid extension absent of HIV-1 Nef. To estimate the influence
Beyer, C. +6 more
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Journal of Medical Primatology, Volume 55, Issue 5, October 2026.ABSTRACT Introduction Natural hosts of simian immunodeficiency virus (SIV), including sooty mangabeys (SMs), maintain high viremia without progressing to AIDS and AIDS‐associated histopathogenesis. The mechanisms underlying this protection and lack of pathogenesis remain incompletely understood, particularly in relation to monocyte/macrophage ...
Caroline Soulas +7 more
wiley +1 more source
, 1983 Nef Frédéric. Présentation. In: Histoire Épistémologie Langage, tome 5, fascicule 2, 1983. La sémantique logique : Problèmes d'histoire et de méthode, sous la direction de Frédéric Nef.
Nef, Frédéric
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SIV Nef proteins recruit the AP-2 complex to antagonize Tetherin and facilitate virion release.
PLoS Pathogens, 2011 Lentiviral Nef proteins have multiple functions and are important for viral pathogenesis. Recently, Nef proteins from many simian immunodefiency viruses were shown to antagonize a cellular antiviral protein, named Tetherin, that blocks release of viral ...
Fengwen Zhang +5 more
doaj +1 more source
HIV-1 Nef protein and the Nef-associating kinase PAK2 in cell signaling [PDF]
, 2010 HIV- eli immuunikatovirustartuntaa kantaa maailmassa arviolta yli 30 miljoonaa ihmistä. Suomessa ilmoituksia HIV-positiivisista henkilöistä oli vuoden 2010 alkuun mennessä kirjattu runsas kolme tuhatta, ja määrä on viime vuosina lisääntynyt noin ...
Pulkkinen, Kati
core
Potent Enhancement of HIV-1 Replication by Nef in the Absence of SERINC3 and SERINC5
mBio, 2019 It has recently emerged that HIV-1 Nef counteracts the antiviral host proteins SERINC3 and SERINC5. In particular, SERINC5 inhibits the infectivity of progeny virions when incorporated.
Yuanfei Wu +5 more
doaj +1 more source
, 2018 La nef comporte 11 travées sensiblement égales, limitées par de solides piliers composés, au flanc desquels un faisceau de colonnettes monte, d’un jet, pour recevoir, bien haut, les retombées des voûtes d’ogives, donnant à l’édifice le bel élan vertical ...
Le Maho, Jacques +1 more
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