Results 61 to 70 of about 109,824 (227)
Acta Psychiatrica Scandinavica, EarlyView.ABSTRACT Aims Characterising the association between childhood maltreatment (CM) and cognitive functioning in bipolar disorder (BD) is crucial for improving the understanding of how early environmental risk factors impact the presentation of the disorder.
Natalia E. Fares‐Otero +7 more
wiley +1 more source
The role of iron in normal and impaired testicular function
Andrology, EarlyView.Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer +2 more
wiley +1 more source
HIV Nef Expression Down-modulated GFAP Expression and Altered Glutamate Uptake and Release and Proliferation in Astrocytes [PDF]
, 2022 Kelly M. Wilson, Johnny J. He
openalex +1 more source
Annals of Public and Cooperative Economics, EarlyView.Abstract Many policymakers are unwilling, or think that it is infeasible, to perform comprehensive cost–benefit analysis (CBA) of programmes in social policy arenas. What principles actually underlie CBA? An understanding is necessary to assess whether other evaluation methods are close enough to CBA to provide useful information on social efficiency ...
Aidan R. Vining, Anthony E. Boardman
wiley +1 more source
Master recherche Histoire du monde méditerranéen médiéval, 2020 Annliese Nef est maîtresse de conférences depuis 2012 à Paris 1, habilitée à diriger des recherches. Elle est spécialiste d’histoire de l’Occident islamique et de la Sicile médiévale (IXe-XIIIe siècle), et des processus d’islamisation aux premiers siècles de l’Islam. Elle a notamment publié avec H. Bresc, Al-Idrîsî, La première géographie de l’Occident,
openaire +1 more source
Cost‐benefit analysis to provide decision criteria: A case study of municipalities in Japan
Annals of Public and Cooperative Economics, EarlyView.Abstract This study explores the use of cost‐benefit analysis (CBA) as a decision‐making tool by deriving boundary values that distinguish positive and negative policy outcomes. While traditional CBA relies on fully quantifiable inputs, this approach focuses on providing reference values for uncertain variables, using CO2 emission reductions as an ...
Shin‐ichi Hanada
wiley +1 more source
The ALS‐associated E425K mutation uncouples DNAJC7 from the Hsp70 chaperone cycle
The FEBS Journal, EarlyView.DNAJC7 is a J‐domain protein that plays a key role in protein quality control by regulating Hsp70 activity and preventing protein aggregation. We find that the ALS‐associated E425K mutation in DNAJC7 disrupts productive interaction and activation of Hsp70, thereby blocking the transfer and refolding of client proteins such as TDP‐43.
Bar Elmaleh +2 more
wiley +1 more source
HIV Medicine, EarlyView.Abstract Introduction A proportion of people living with HIV (PLWH) fail to restore their CD4 count or their CD4/CD8 ratio despite effective antiretroviral therapy (ART). PLWH with immune non‐response (INR) are at a higher risk of both AIDS and non‐AIDS events. The underlying mechanisms of INR remain unclear.
Charlotte Silvestre +2 more
wiley +1 more source
Nef‘î’nin Şiirinde Siyaset Düşüncesi ve Memduhun İstidadı Olarak Cevher
Turcology ResearchCevher Antik Yunan döneminden bu yana felsefenin konusu olmuştur. Aristoteles’in Kategoriler’de etraflıca belirttiği fikirleri cevherin asla bir mevzuda bulunmaması ilkesine dayanmaktadır. Bütün arazların kendisine yüklendiği temel kategori olan cevherin
Hilal Yiğit
doaj +1 more source