Transcriptome Analysis Reveals That NEFA and β-Hydroxybutyrate Induce Oxidative Stress and Inflammatory Response in Bovine Mammary Epithelial Cells [PDF]
Non-esterified fatty acids (NEFA) and β-hydroxybutyrate (BHBA) are the metabolites of fat mobilization initiated by negative energy balance (NEB) during the perinatal period in dairy cows, which have an adverse effect on cell physiology of various bovine
Chengmin Li+5 more
doaj +3 more sources
NDUFAB1 as a Novel Regulator of NEFA-Induced Metabolic Dysfunction in Bovine Adipocytes [PDF]
Elevated non-esterified fatty acid (NEFA) levels are closely associated with metabolic disorders in dairy cattle, yet their direct effects on adipocyte physiology remain poorly understood.
Jing Zhou+6 more
doaj +3 more sources
Quantitative and qualitative analysis of human salivary NEFA with gas-chromatography and mass spectrometry [PDF]
Salivary NEFA are proposed to play a role in oral health, oral fat detection, and they may hold diagnostic and prognostic potential. Yet, little is known about the array and concentrations of NEFA in saliva.
Bhushan V Kulkarni+2 more
doaj +3 more sources
Intrahepatic Lipid Content and Insulin Resistance Are More Strongly Associated with Impaired NEFA Suppression after Oral Glucose Loading Than with Fasting NEFA Levels in Healthy Older Individuals [PDF]
Introduction. The mechanisms underlying the association between insulin resistance and intrahepatic lipid (IHL) accumulation are not completely understood.
Francis M. Finucane+9 more
doaj +2 more sources
Association of precalving serum NEFA concentrations with postpartum diseases and reproductive performance in multiparous Holstein cows: Cut‐off values [PDF]
Background High concentrations of NEFA relative to a defined reference or ‘cut‐point’ values before calving can predict the risk of specific or collective periparturient disease events.
Samuel Kia, Mehrdad Mohri, Hesam A Seifi
doaj +2 more sources
Isorhamnetin Ameliorates Non-Esterified Fatty Acid-Induced Apoptosis, Lipid Accumulation, and Oxidative Stress in Bovine Endometrial Epithelial Cells via Inhibiting the MAPK Signaling Pathway [PDF]
High concentrations of non-esterified fatty acids (NEFA) in the blood contribute to various metabolic disorders and are linked to endometritis in dairy cows.
Haimiao Lv+7 more
doaj +2 more sources
The In Vitro Effects of Choline on Non-Esterified Fatty Acid-Treated Bovine Peripheral Blood Leukocytes [PDF]
The transition period is defined as 3 weeks around parturition, involving the rapid increase in the energy demand, promoting adipose mobilization and non-esterified fatty acid (NEFA) release.
Cheng-Yan Li+4 more
doaj +2 more sources
Adipocytes regulate monocyte development through the OGT-NEFA-CD36/FABP4 pathway in high-fat diet-induced obesity. [PDF]
He N, Li Y, Liu F, Dong X, Ma D.
europepmc +2 more sources
Biochemical abnormality in the Brown Swiss breed cows affected with ketosis in the perinatal period
Ketosis is widespread disturbance among dairy cows, causing significant economic losses and requiring further study of its pathogenesis. This particularly applies to less traditional dairy breeds, including the Brown Swiss.
V. H. Yefimov
doaj +1 more source
Resveratrol Alleviates NEFA-Induced Oxidative Damage in Bovine Mammary Epithelial Cells by Restoring Mitochondrial Function. [PDF]
Sun L+8 more
europepmc +2 more sources