Results 11 to 20 of about 4,598,204 (290)

What Kind of Students Attend Cyber Schools? Pandemic Enrollment as Evidence of Negative Selection

open access: yesFrontiers in Education, 2022
Fully online virtual schools have consistently underperformed academically compared to brick and mortar schools. Scholars debate the extent to which these differences are due school quality or the type of student that attends virtual schools.
Ian Kingsbury   +2 more
doaj   +1 more source

Thymic B Cells as a New Player in the Type 1 Diabetes Response

open access: yesFrontiers in Immunology, 2021
Type 1 diabetes (T1d) results from a sustained autoreactive T and B cell response towards insulin-producing β cells in the islets of Langerhans. The autoreactive nature of the condition has led to many investigations addressing the genetic or cellular ...
Richard B. Greaves   +2 more
doaj   +1 more source

Classification Software Engineering Documents Based on Hybrid Model [PDF]

open access: yesAl-Rafidain Journal of Computer Sciences and Mathematics, 2018
Care about automated documents classification has increased since the appearance of the digital documents and the wide diffusion of Internet. In the 1990's, the computer performance has greatly improved and has led to the methods of machine learning to ...
Nada Saleem, Rasha Saeed
doaj   +1 more source

Molecular mutation features of influenza B viruses in Guangdong, 2020-2021

open access: yes陆军军医大学学报, 2022
Objective To learn the molecular characteristics of influenza B Victoria lineage (Bv) and evaluate the influenza B spread trend about the epidemic. Methods Based on the Guangdong Influenza Surveillance Networks (GDISN) to selected the Bv with space-time
TAN Jing   +4 more
doaj   +1 more source

Mitogenome evolution in ladybirds: Potential association with dietary adaptation

open access: yesEcology and Evolution, 2020
Dietary shifts can alter the relative availability of different nutrients and are therefore associated with metabolic adaptation in animals. The Coccinellidae (ladybirds) exhibits three major types of feeding habits and provides a useful model to study ...
Ming‐Long Yuan   +7 more
doaj   +1 more source

Chloroplast genome assembly of Serjania erecta Raldk: comparative analysis reveals gene number variation and selection in protein-coding plastid genes of Sapindaceae

open access: yesFrontiers in Plant Science, 2023
Serjania erecta Raldk is an essential genetic resource due to its anti-inflammatory, gastric protection, and anti-Alzheimer properties. However, the genetic and evolutionary aspects of the species remain poorly known. Here, we sequenced and assembled the
Leonardo C. J. Corvalán   +14 more
doaj   +1 more source

MHC Class II Presentation in Autoimmunity

open access: yesCells, 2023
Antigen presentation by major histocompatibility complex class II (MHC-II) molecules is crucial for eliciting an efficient immune response by CD4+ T cells and maintaining self-antigen tolerance.
Irina A. Ishina   +5 more
doaj   +1 more source

A conditional marker gene allowing both positive and negative selection in plants [PDF]

open access: yes, 2004
Selectable markers enable transgenic plants or cells to be identified after transformation. They can be divided into positive and negative markers conferring a selective advantage or disadvantage, respectively.
Erikson, Oskar   +2 more
core   +1 more source

Site-specific selection reveals selective constraints and functionality of tumor somatic mtDNA mutations. [PDF]

open access: yes, 2017
BACKGROUND: Previous studies have indicated that tumor mitochondrial DNA (mtDNA) mutations are primarily shaped by relaxed negative selection, which is contradictory to the critical roles of mtDNA mutations in tumorigenesis.
Chen, Cheng   +10 more
core   +2 more sources

Use of signals of positive and negative selection to distinguish cancer genes and passenger genes

open access: yeseLife, 2021
A major goal of cancer genomics is to identify all genes that play critical roles in carcinogenesis. Most approaches focused on genes positively selected for mutations that drive carcinogenesis and neglected the role of negative selection.
László Bányai   +4 more
doaj   +1 more source

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