Negative priming without probe selection [PDF]
Responses to an object may be slower or less accurate if that object shares attributes with a recently ignored object(negative priming). Some studies have found negative priming only if the probe trial required selection against a distractor stimulus. In the present experiment, subjects responded to the location of a target (O), ignoring a distractor ...
W T, Neill, K M, Terry, L A, Valdes
openaire +2 more sources
Negative and positive selection of antigen-specific cytotoxic T lymphocytes affected by the α3 domain of MHC I molecules [PDF]
THE α1 and α2 domains of major histocompatibility complex (MHC) class I molecules function in the binding and presentation of foreign peptides to the T-cell antigen receptor and control both negative and positive selection of the T-cell repertoire ...
AM Norment +30 more
core +1 more source
Detecting Past Positive Selection through Ongoing Negative Selection [PDF]
Detecting positive selection is a challenging task. We propose a method for detecting past positive selection through ongoing negative selection, based on comparison of the parameters of intraspecies polymorphism at functionally important and selectively neutral sites where a nucleotide substitution of the same kind occurred recently.
Bazykin, Georgii A. +1 more
openaire +2 more sources
The Occurrence of the Viruses in Tulip Crops in Poland
The viruses infecting tulips have a big influence on the yield and the quality of bulbs and forced flowers. Commercial bulb production is based on clonal propagation, which leads to the accumulation of viruses.
Sochacki Dariusz
doaj +1 more source
Destabilizing the autoinhibitory conformation of Zap70 induces up-regulation of inhibitory receptors and T cell unresponsiveness. [PDF]
Zap70 plays a critical role in normal T cell development and T cell function. However, little is known about how perturbation of allosteric autoinhibitory mechanisms in Zap70 impacts T cell biology.
Chen, Yiling +4 more
core +2 more sources
A role for phagocytosis in inducing cell death during thymocyte negative selection
Autoreactive thymocytes are eliminated during negative selection in the thymus, a process important for establishing self-tolerance. Thymic phagocytes serve to remove dead thymocytes, but whether they play additional roles during negative selection ...
Nadia S Kurd +6 more
doaj +1 more source
Autoreactive CD4+ T cells initiate the chronic autoimmune disease Type-1 diabetes (T1D), in which multiple environmental and genetic factors are involved. The association of HLA, especially the DR-DQ loci, with risk for T1D is well documented.
Peter Edward Jensen, Zemin eZhou
doaj +1 more source
Possible ramifications of introducing the institute of personal bankruptcy: The USA experience [PDF]
In the past decade, the increase of household debt in Serbia as well as in the entire region has brought the issue of personal bankruptcy into the spotlight.
Mizdraković Vule
doaj +1 more source
Metallothioneins (MTs) are low-molecular weight sulfur-rich proteins, widely distributed in nature. They play a homeostatic role in the control and detoxification of metal ions.
Rigers Bakiu +9 more
doaj +1 more source
ZRT1 harbors an excess of nonsynonymous polymorphism and shows evidence of balancing selection in Saccharomyces cerevisiae [PDF]
Estimates of the fraction of nucleotide substitutions driven by positive selection vary widely across different species. Accounting for different estimates of positive selection has been difficult, in part because selection on polymorphism within a ...
Engle, Elizabeth K., Fay, Justin C.
core +3 more sources

