Results 121 to 130 of about 342 (145)
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Perforating dermatosis in a patient on haemodialysis successfully treated with nemolizumab
Clinical and Experimental Dermatology, 2023We present a case of perforating dermatosis in a patient with uraemic pruritus who was on haemodialysis and who was successfully treated with nemolizumab, a humanized monoclonal antibody targeted against interleukin-31 receptor A. Nemolizumab may be a treatment option for perforating dermatosis with a uraemic pruritus background. To our knowledge, this
Shun, Ohmori, Yu, Sawada
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BACKGROUND: Nemolizumab, an interleukin (IL)-31 receptor subunit α antagonist, inhibits the IL-31 pathway of itch and skin inflammation in atopic dermatitis.
Liliana Ulianov, Soo Yeon Cheong
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Clinical and Experimental Dermatology, 2023
The pathogenesis of acquired perforating dermatosis remains unknown and management is challenging. Traditional treatment includes antihistamines, allopurinol, corticosteroids, retinoids, doxycycline, keratolytic agents and phototherapy but with limited efficacy in some patients. Recently, developments in biologics and small-molecule drugs have provided
Li-Wen, Zhang, Juan, Wu, Tao, Chen
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The pathogenesis of acquired perforating dermatosis remains unknown and management is challenging. Traditional treatment includes antihistamines, allopurinol, corticosteroids, retinoids, doxycycline, keratolytic agents and phototherapy but with limited efficacy in some patients. Recently, developments in biologics and small-molecule drugs have provided
Li-Wen, Zhang, Juan, Wu, Tao, Chen
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Atopic Dermatitis Flare Following Initiation of Nemolizumab
Journal of Drugs in DermatologyAtopic dermatitis (AD) is a chronic inflammatory skin disorder marked by intense pruritus and episodic flares. While nemolizumab, an interleukin-31 (IL-31) inhibitor, has demonstrated efficacy in reducing itch severity, its broader effects on skin inflammation are not fully understood.We describe a 49-year-old male with longstanding, treatment ...
Olivia M, Burke +2 more
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Canadian Journal of Health Technologies
Reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class. The assessments inform nonbinding recommendations that help guide the reimbursement decisions of Canada’s federal, provincial, and territorial governments, with the exception ...
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Reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class. The assessments inform nonbinding recommendations that help guide the reimbursement decisions of Canada’s federal, provincial, and territorial governments, with the exception ...
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Aim Nemolizumab is a novel drug used for the treatment of chronic prurigo. Using the FDA Adverse Event Reporting System (FAERS) database, this research examined adverse drug events (ADEs) related to nemolizumab in order to pinpoint potential safety signals. Methods Nemolizumab was
Xiaoting Li, Weiling Chen, Xingwu Duan
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Xiaoting Li, Weiling Chen, Xingwu Duan
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Nemolizumab (Nemluvio) for Atopic Dermatitis
The Medical Letter on Drugs and TherapeuticsNemolizumab (Nemluvio – Galderma), a subcutaneously injected interleukin-31 (IL-31) receptor antagonist, has been approved by the FDA for use in combination with topical corticosteroids and/or calcineurin inhibitors for treatment of moderate to severe atopic dermatitis in patients ≥12 years old whose disease is not adequately controlled with topical ...
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Learning From Nemolizumab: A Promising Therapy for Prurigo Nodularis
Journal of Allergy and Clinical ImmunologyBrian S Kim
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Use of Nemolizumab in Refractory Scrotal Dysesthesia
JAMA DermatologyThis case report describes 2 patients with refractory scrotal dysesthesia treated with nemolizumab.
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