Results 1 to 10 of about 115,708 (268)

Piezo2—peripheral baroreceptor channel expressed in select neurons of the mouse brain: a putative mechanism for synchronizing neural networks by transducing intracranial pressure pulses

open access: yesJournal of Integrative Neuroscience, 2021
Here we use immunohistochemistry to examine the expression of Piezo2 in neurons of the mouse dorsal root ganglia and brain. Whereas Piezo2 is expressed in the large majority (≥ 90%) of dorsal root ganglia neurons, Piezo2 expression is restricted to ...
Jigong Wang   +1 more
doaj   +1 more source

Neurotransmitters as Modulators of Neural Progenitor Cell Proliferation During Mammalian Neocortex Development

open access: yesFrontiers in Cell and Developmental Biology, 2020
Neural progenitor cells (NPCs) play a central role during the development and evolution of the mammalian neocortex. Precise temporal and spatial control of NPC proliferation by a concert of cell-intrinsic and cell-extrinsic factors is essential for the ...
Lei Xing, Wieland B. Huttner
doaj   +1 more source

Neocortical tissue recovery in severe congenital obstructive hydrocephalus after intraventricular administration of bone marrow-derived mesenchymal stem cells [PDF]

open access: yes, 2020
BACKGROUND: In obstructive congenital hydrocephalus, cerebrospinal fluid accumulation is associated with high intracranial pressure and the presence of periventricular edema, ischemia/hypoxia, damage of the white matter, and glial reactions in the ...
Cifuentes, Manuel   +12 more
core   +2 more sources

Morphofunctional Characteristic of Edema-Swelling of the Cerebral Cortex of White Rats After Severe Traumatic Brain Injury Without the Use of L-Lysine Escinate and Against the Background of Its Use

open access: yesНеотложная медицинская помощь, 2020
Aim of study The study is devoted to a morphometric assessment of the manifestations of edema-swelling of the somatosensory cortex (SSC) of the brain of white rats after severe traumatic brain injury (TBI) without using L-lysine escinate and when using ...
I. P. Koshman   +6 more
doaj   +1 more source

Transgenerational Effects of Prenatal Ethanol Exposure in Prepubescent Mice

open access: yesFrontiers in Cell and Developmental Biology, 2022
Background: Fetal alcohol spectrum disorders (FASD) represent a leading cause of non-genetic neuropathologies. Recent preclinical evidence from suggests that prenatal ethanol exposure (PrEE), like other environmental exposures, may have a significant ...
Riley T. Bottom   +5 more
doaj   +1 more source

Cholinergic Internal and Projection Systems of Hippocampus and Neocortex Critical for Early Spatial Memory Consolidation in Normal and Chronic Cerebral Hypoperfusion Conditions in Rats with Different Abilities to Consolidation: The Role of Cholinergic Interneurons of the Hippocampus

open access: yesBiomedicines, 2022
The role of cholinergic projection systems of the neocortex and hippocampus in memory consolidation in healthy and neuropathological conditions has been subject to intensive research.
Elena I. Zakharova   +3 more
doaj   +1 more source

Roots of the Malformations of Cortical Development in the Cell Biology of Neural Progenitor Cells

open access: yesFrontiers in Neuroscience, 2022
The cerebral cortex is a structure that underlies various brain functions, including cognition and language. Mammalian cerebral cortex starts developing during the embryonic period with the neural progenitor cells generating neurons.
Chiara Ossola, Nereo Kalebic
doaj   +1 more source

Human-specific ARHGAP11B induces hallmarks of neocortical expansion in developing ferret neocortex

open access: yeseLife, 2018
The evolutionary increase in size and complexity of the primate neocortex is thought to underlie the higher cognitive abilities of humans. ARHGAP11B is a human-specific gene that, based on its expression pattern in fetal human neocortex and progenitor ...
Nereo Kalebic   +7 more
doaj   +1 more source

A Framework for Intelligence and Cortical Function Based on Grid Cells in the Neocortex

open access: yesFrontiers in Neural Circuits, 2019
How the neocortex works is a mystery. In this paper we propose a novel framework for understanding its function. Grid cells are neurons in the entorhinal cortex that represent the location of an animal in its environment.
Jeff Hawkins   +4 more
doaj   +1 more source

Why Neurons Have Thousands of Synapses, A Theory of Sequence Memory in Neocortex [PDF]

open access: yes, 2015
Neocortical neurons have thousands of excitatory synapses. It is a mystery how neurons integrate the input from so many synapses and what kind of large-scale network behavior this enables.
Ahmad, Subutai, Hawkins, Jeff
core   +3 more sources

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