Results 31 to 40 of about 68,495 (293)

EZcalcium: Open-Source Toolbox for Analysis of Calcium Imaging Data

Frontiers in Neural Circuits, 2020
Fluorescence calcium imaging using a range of microscopy approaches, such as two-photon excitation or head-mounted “miniscopes,” is one of the preferred methods to record neuronal activity and glial signals in various experimental settings, including ...
Daniel A. Cantu, Daniel A. Cantu, Bo Wang, Michael W. Gongwer, Michael W. Gongwer, Cynthia X. He, Cynthia X. He, Anubhuti Goel, Anand Suresh, Nazim Kourdougli, Erica D. Arroyo, Erica D. Arroyo, William Zeiger, Carlos Portera-Cailliau, Carlos Portera-Cailliau   +14 more
doaj   +1 more source

Basal Progenitor Morphology and Neocortex Evolution.

, 2020
The evolutionary expansion of the mammalian neocortex is widely considered to be a basis of increased cognitive abilities. This expansion is a consequence of the enhanced production of neurons during the fetal/embryonic development of the neocortex ...
Kalebic, N., Huttner, W.
core   +1 more source

Human-specific ARHGAP11B increases size and folding of primate neocortex in the fetal marmoset.

, 2020
The neocortex has expanded during mammalian evolution. Overexpression studies in developing mouse and ferret neocortex have implicated the human-specific gene ARHGAP11B in neocortical expansion, but the relevance for primate evolution has been unclear ...
Kurotaki, Y., Sasaki, E., Haffner, C., Huttner, W., Murayama, A., Heide, M., Okano, H., Shinohara, H.   +7 more
core   +1 more source

Layer 2/3 Pyramidal Neurons of the Mouse Granular Retrosplenial Cortex and Their Innervation by Cortico-Cortical Axons

Frontiers in Neural Circuits, 2020
The retrosplenial cortex forms part of the cingulate cortex and is involved in memory and navigation. It is ventral region, the granular retrosplenial cortex, or GRSC is characterized by the presence, of small pyramidal neurons with a distinctive late ...
Rita M. Robles, Eduardo Domínguez-Sala, Salvador Martínez, Salvador Martínez, Emilio Geijo-Barrientos   +4 more
doaj   +1 more source

Heterosynaptic plasticity in the neocortex [PDF]

Experimental Brain Research, 2009
Ongoing learning continuously shapes the distribution of neurons' synaptic weights in a system with plastic synapses. Plasticity may change the weights of synapses that were active during the induction-homosynaptic changes, but also may change synapses not active during the induction-heterosynaptic changes.
Chistiakova, Marina, Volgushev, Maxim
openaire   +2 more sources

A Canonical Laminar Neocortical Circuit Whose Bottom-Up, Horizontal, and Top-Down Pathways Control Attention, Learning, and Prediction

Frontiers in Systems Neuroscience, 2021
All perceptual and cognitive circuits in the human cerebral cortex are organized into layers. Specializations of a canonical laminar network of bottom-up, horizontal, and top-down pathways carry out multiple kinds of biological intelligence across ...
Stephen Grossberg
doaj   +1 more source

Neuroplasticity Meets Artificial Intelligence: A Hippocampus-Inspired Approach to the Stability–Plasticity Dilemma

Brain Sciences
The stability–plasticity dilemma remains a critical challenge in developing artificial intelligence (AI) systems capable of continuous learning. This perspective paper presents a novel approach by drawing inspiration from the mammalian hippocampus–cortex
Thorsten Rudroff, Oona Rainio, Riku Klén   +2 more
doaj   +1 more source

Infrabarrels Are Layer 6 Circuit Modules in the Barrel Cortex that Link Long-Range Inputs and Outputs

Cell Reports, 2017
The rodent somatosensory cortex includes well-defined examples of cortical columns—the barrel columns—that extend throughout the cortical depth and are defined by discrete clusters of neurons in layer 4 (L4) called barrels.
Shane R. Crandall, Saundra L. Patrick, Scott J. Cruikshank, Barry W. Connors   +3 more
doaj   +1 more source

Thalamocortical axons control the cytoarchitecture of neocortical layers by area-specific supply of VGF

eLife, 2022
Neuronal abundance and thickness of each cortical layer are specific to each area, but how this fundamental feature arises during development remains poorly understood.
Haruka Sato, Jun Hatakeyama, Takuji Iwasato, Kimi Araki, Nobuhiko Yamamoto, Kenji Shimamura   +5 more
doaj   +1 more source

Zolpidem Activation of Alpha 1-Containing GABAA Receptors Selectively Inhibits High Frequency Action Potential Firing of Cortical Neurons

Frontiers in Pharmacology, 2019
Introduction: High frequency neuronal activity in the cerebral cortex can be induced by noxious stimulation during surgery, brain injury or poisoning. In this scenario, it is essential to block cortical hyperactivity to protect the brain against damage ...
Elena Neumann, Uwe Rudolph, Daniel E. Knutson, Guanguan Li, James M. Cook, Harald Hentschke, Bernd Antkowiak, Bernd Antkowiak, Berthold Drexler   +8 more
doaj   +1 more source